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Q91XW7 (Q91XW7_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Caspase PIRNR PIRNR038001
Gene names
Name:Casp4 RGD 621757
Synonyms:Casp11 EMBL AAK38735.1
OrganismRattus norvegicus (Rat) EMBL AAK38735.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase C14A family. PIRNR PIRNR038001 RuleBase RU003971

Contains CARD domain. SAAS SAAS011029

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2061 By similarity PIRSR PIRSR038001-1
Active site2541 By similarity PIRSR PIRSR038001-1

Sequences

Sequence LengthMass (Da)Tools
Q91XW7 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 9D0F6B3EDFED7592

FASTA37342,690
        10         20         30         40         50         60 
MAENNHPDKP LKVLEELGKE FLTEYLEKLV QSNVLKLKEE EKQKFNNAER SDKRWVFVDV 

        70         80         90        100        110        120 
LKRKHNQVGK MLLQTFLNVD SGSHHGEANL EMEEPEESVD TLKLCSSEEF TRLCREKKQE 

       130        140        150        160        170        180 
IYPIKETNGR TRKALIICNT EFKHLSLRYG ANIDISGMKG LLEELGYDVV VKEELTAEGM 

       190        200        210        220        230        240 
ESEMKDFAAL SEHQTSDSTF LVVMSHGTLQ GLCGTMHSEA TPDVLLYDTI YQIFNNCHCP 

       250        260        270        280        290        300 
GLRDKPKVII VQACRGGNSG EVWIRESSGA HSYRAVDLPR NMEADAVRMS HVEKDFIALY 

       310        320        330        340        350        360 
STTPHHLSYR DKTRGSYFIS KLISCFRIHA CSCHLFDIFL KVQQSFEKAS INSQMPTIDR 

       370 
ATLTRYFYLF PGN 

« Hide

References

[1]"Induction of caspase-11 by inflammatory stimuli in rat astrocytes: lipopolysaccharide induction through p38 mitogen-activated protein kinase pathway."
Hur J., Kim S.Y., Kim H., Cha S., Lee M.S., Suk K.
FEBS Lett. 507:157-162(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Glioma EMBL AAK38735.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY029283 mRNA. Translation: AAK38735.1.
UniGeneRn.16195.

3D structure databases

ProteinModelPortalQ91XW7.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSC14.012.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCRGD:621757. rat.

Organism-specific databases

RGD621757. Casp4.

Phylogenomic databases

HOVERGENHBG076981.
InParanoidQ91XW7.
PhylomeDBQ91XW7.

Enzyme and pathway databases

BRENDA3.4.22.64. 248.

Gene expression databases

GenevestigatorQ91XW7.

Family and domain databases

Gene3D1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProIPR001315. CARD.
IPR029030. Caspase-like_dom.
IPR017350. Caspase_ICE-type.
IPR011029. DEATH-like_dom.
IPR011600. Pept_C14_caspase.
IPR001309. Pept_C14_ICE_p20.
IPR016129. Pept_C14_ICE_p20_AS.
IPR002138. Pept_C14_p10.
IPR015917. Pept_C14A_p45_core.
[Graphical view]
PfamPF00619. CARD. 1 hit.
PF00656. Peptidase_C14. 1 hit.
[Graphical view]
PIRSFPIRSF038001. Caspase_ICE. 1 hit.
PRINTSPR00376. IL1BCENZYME.
SMARTSM00114. CARD. 1 hit.
SM00115. CASc. 1 hit.
[Graphical view]
SUPFAMSSF47986. SSF47986. 1 hit.
PROSITEPS50209. CARD. 1 hit.
PS01122. CASPASE_CYS. 1 hit.
PS01121. CASPASE_HIS. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ91XW7_RAT
AccessionPrimary (citable) accession number: Q91XW7
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)