Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q91XT1

- Q91XT1_RAT

UniProt

Q91XT1 - Q91XT1_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

CREB-binding protein

Gene

Crebbp

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: Ensembl
  2. core promoter proximal region sequence-specific DNA binding Source: Ensembl
  3. histone acetyltransferase activity Source: Ensembl
  4. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: Ensembl
  5. RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription Source: Ensembl
  6. transcription coactivator activity Source: Ensembl

GO - Biological processi

  1. germ-line stem cell maintenance Source: Ensembl
  2. N-terminal peptidyl-lysine acetylation Source: Ensembl
  3. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_196232. Factors involved in megakaryocyte development and platelet production.
REACT_196250. TRAF6 mediated IRF7 activation.
REACT_196405. BMAL1:CLOCK,NPAS2 activates circadian gene expression.
REACT_196408. PPARA activates gene expression.
REACT_196852. REV-ERBA represses gene expression.
REACT_196856. RORA activates circadian gene expression.
REACT_198375. LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production.
REACT_198384. HATs acetylate histones.
REACT_198613. Activation of gene expression by SREBF (SREBP).
REACT_198659. NOTCH1 Intracellular Domain Regulates Transcription.
REACT_198750. Constitutive Signaling by NOTCH1 PEST Domain Mutants.
REACT_198752. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
REACT_198793. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_199199. Regulation of gene expression by Hypoxia-inducible Factor.
REACT_206546. Attenuation phase.
REACT_216049. Transcriptional activation of mitochondrial biogenesis.
REACT_226234. formation of the beta-catenin:TCF transactivating complex.

Names & Taxonomyi

Protein namesi
Submitted name:
CREB-binding proteinImported
Gene namesi
Name:CrebbpImported
Synonyms:CBPImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2401. Crebbp.

Subcellular locationi

GO - Cellular componenti

  1. condensed chromosome outer kinetochore Source: Ensembl
  2. cytoplasm Source: Ensembl
  3. histone acetyltransferase complex Source: Ensembl
  4. nuclear body Source: Ensembl
  5. nuclear chromatin Source: Ensembl
  6. transcription factor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ91XT1. baseline.
GenevestigatoriQ91XT1.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007079.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG074064.
PhylomeDBiQ91XT1.

Sequencei

Sequence statusi: Complete.

Q91XT1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAENLLDGPP NPKRAKLSSP GFSANDSTDF GSLFDLENDL PDELIPNGEL
60 70 80 90 100
SLLNSGNLVP DAASKHKQLS ELLRGGSGSS ITPGIGNVSA SSPVQQGLGG
110 120 130 140 150
QAQGQPNSTS MASLGAMGKS PLNPGDSSTP SLPKQAASTS GPTPPASQAL
160 170 180 190 200
NPQAQKQVGL VTSSPATSQT GPGICMNANF NQTHPGLLNS NSGHSLMNQA
210 220 230 240 250
QQGQAQVMNG SLGAAGRGRG AGMPYPAPAM QGATSSVLAE TLTQVSPQMA
260 270 280 290 300
GHAGLNTAQA GGMTKMGMTG NTSPFGQPFS QTGGQPMGAT GVNPQLASKQ
310 320 330 340 350
SMVNSLPAFP TDIKNTSVTT VPNMSQLQTS VGIVPAQGIA TGPTADPEKR

K
Length:351
Mass (Da):35,189
Last modified:December 1, 2001 - v1
Checksum:iFFDCDCAA2506ED7F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB066219 mRNA. Translation: BAB62424.1.
UniGeneiRn.12815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB066219 mRNA. Translation: BAB62424.1 .
UniGenei Rn.12815.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000007079.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 2401. Crebbp.

Phylogenomic databases

HOVERGENi HBG074064.
PhylomeDBi Q91XT1.

Enzyme and pathway databases

Reactomei REACT_196232. Factors involved in megakaryocyte development and platelet production.
REACT_196250. TRAF6 mediated IRF7 activation.
REACT_196405. BMAL1:CLOCK,NPAS2 activates circadian gene expression.
REACT_196408. PPARA activates gene expression.
REACT_196852. REV-ERBA represses gene expression.
REACT_196856. RORA activates circadian gene expression.
REACT_198375. LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production.
REACT_198384. HATs acetylate histones.
REACT_198613. Activation of gene expression by SREBF (SREBP).
REACT_198659. NOTCH1 Intracellular Domain Regulates Transcription.
REACT_198750. Constitutive Signaling by NOTCH1 PEST Domain Mutants.
REACT_198752. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
REACT_198793. YAP1- and WWTR1 (TAZ)-stimulated gene expression.
REACT_199199. Regulation of gene expression by Hypoxia-inducible Factor.
REACT_206546. Attenuation phase.
REACT_216049. Transcriptional activation of mitochondrial biogenesis.
REACT_226234. formation of the beta-catenin:TCF transactivating complex.

Gene expression databases

ExpressionAtlasi Q91XT1. baseline.
Genevestigatori Q91XT1.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Major intestinal coactivator p300 strongly activates peroxisome proliferator-activated receptor in intestinal cell line, Caco-2."
    Mochizuki K., Suruga K., Sakaguchi N., Takase S., Goda T.
    Gene 291:271-277(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Small intestineImported.

Entry informationi

Entry nameiQ91XT1_RAT
AccessioniPrimary (citable) accession number: Q91XT1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)