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Q91XQ6

- LAP4B_MOUSE

UniProt

Q91XQ6 - LAP4B_MOUSE

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Protein
Lysosomal-associated transmembrane protein 4B
Gene
Laptm4b
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Lysosomal-associated transmembrane protein 4B
Gene namesi
Name:Laptm4b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:1890494. Laptm4b.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4621Helical; Reviewed prediction
Add
BLAST
Transmembranei72 – 9221Helical; Reviewed prediction
Add
BLAST
Transmembranei100 – 12021Helical; Reviewed prediction
Add
BLAST
Transmembranei153 – 17321Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. endomembrane system Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 227227Lysosomal-associated transmembrane protein 4B
PRO_0000249723Add
BLAST

Proteomic databases

PRIDEiQ91XQ6.

PTM databases

PhosphoSiteiQ91XQ6.

Expressioni

Gene expression databases

ArrayExpressiQ91XQ6.
BgeeiQ91XQ6.
CleanExiMM_LAPTM4B.
GenevestigatoriQ91XQ6.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG46169.
GeneTreeiENSGT00390000013359.
HOGENOMiHOG000007698.
HOVERGENiHBG000908.
InParanoidiQ91XQ6.
KOiK12387.
OMAiTIILGIW.
OrthoDBiEOG7QC7X3.
PhylomeDBiQ91XQ6.
TreeFamiTF330843.

Family and domain databases

InterProiIPR004687. LAPTM4/5.
IPR018401. Lysosomal-assoc_TM_prot4B.
[Graphical view]
PANTHERiPTHR12479. PTHR12479. 1 hit.
PTHR12479:SF6. PTHR12479:SF6. 1 hit.
PfamiPF03821. Mtp. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91XQ6-1 [UniParc]FASTAAdd to Basket

« Hide

MKMVAPWTRF YSHSCCLCCH VRTGTILLGV WYLIINAVVL LILLSALADP    50
NQYHFSGSEL GGEFEFMDDA NMCIAIAISL LMILICAMAT YGAYKQHAAW 100
IIPFFCYQIF DFALNTLVAI TVLVYPNSIQ EYIRQLPPSF PYRDDIMSVN 150
PTCLVLIILL FIGILLTLKG YLISCVWSCY RYINGRNSSD VLVYVTSNDT 200
TVLLPPYDDA TAVPSTAKEP PPPYVSA 227
Length:227
Mass (Da):25,395
Last modified:December 1, 2001 - v1
Checksum:iFD3DC53C2682818D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF317418 mRNA. Translation: AAK69596.1.
AK077269 mRNA. Translation: BAC36721.1.
AK077933 mRNA. Translation: BAC37072.1.
AK079581 mRNA. Translation: BAC37691.1.
AK082807 mRNA. Translation: BAC38630.1.
BC019120 mRNA. Translation: AAH19120.1.
CCDSiCCDS27416.1.
RefSeqiNP_277056.1. NM_033521.3.
UniGeneiMm.197518.

Genome annotation databases

EnsembliENSMUST00000022867; ENSMUSP00000022867; ENSMUSG00000022257.
GeneIDi114128.
KEGGimmu:114128.
UCSCiuc007vlj.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF317418 mRNA. Translation: AAK69596.1 .
AK077269 mRNA. Translation: BAC36721.1 .
AK077933 mRNA. Translation: BAC37072.1 .
AK079581 mRNA. Translation: BAC37691.1 .
AK082807 mRNA. Translation: BAC38630.1 .
BC019120 mRNA. Translation: AAH19120.1 .
CCDSi CCDS27416.1.
RefSeqi NP_277056.1. NM_033521.3.
UniGenei Mm.197518.

3D structure databases

ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q91XQ6.

Proteomic databases

PRIDEi Q91XQ6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000022867 ; ENSMUSP00000022867 ; ENSMUSG00000022257 .
GeneIDi 114128.
KEGGi mmu:114128.
UCSCi uc007vlj.1. mouse.

Organism-specific databases

CTDi 55353.
MGIi MGI:1890494. Laptm4b.

Phylogenomic databases

eggNOGi NOG46169.
GeneTreei ENSGT00390000013359.
HOGENOMi HOG000007698.
HOVERGENi HBG000908.
InParanoidi Q91XQ6.
KOi K12387.
OMAi TIILGIW.
OrthoDBi EOG7QC7X3.
PhylomeDBi Q91XQ6.
TreeFami TF330843.

Miscellaneous databases

ChiTaRSi LAPTM4B. mouse.
NextBioi 368129.
PROi Q91XQ6.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q91XQ6.
Bgeei Q91XQ6.
CleanExi MM_LAPTM4B.
Genevestigatori Q91XQ6.

Family and domain databases

InterProi IPR004687. LAPTM4/5.
IPR018401. Lysosomal-assoc_TM_prot4B.
[Graphical view ]
PANTHERi PTHR12479. PTHR12479. 1 hit.
PTHR12479:SF6. PTHR12479:SF6. 1 hit.
Pfami PF03821. Mtp. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Hogue D.L.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6.
    Tissue: Brain.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Hypothalamus and Testis.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Eye.

Entry informationi

Entry nameiLAP4B_MOUSE
AccessioniPrimary (citable) accession number: Q91XQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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