Q91XL6 (Q91XL6_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphatidylinositol 3-kinase alpha catalytic subunit EMBL AAK83379.1
EC=2.7.1.137 EMBL AAK83379.1

Gene names

Name:

Pik3ca RGD 620916

Organism

Rattus norvegicus (Rat) EMBL AAK83379.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	291 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PI3K/PI4K domain. SAAS SAAS018936

Ontologies

Keywords
Molecular function	Kinase SAAS SAAS018936 EMBL AAK83379.1 Transferase
Gene Ontology (GO)
Biological process	phosphatidylinositol-mediated signaling Inferred from electronic annotation. Source: InterPro
Cellular component	phosphatidylinositol 3-kinase complex Inferred from direct assay. Source: RGD
Molecular function	1-phosphatidylinositol-3-kinase activity Inferred from direct assay. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAK83379.1
	Non-terminal residue	291	1	EMBL AAK83379.1

Sequences

	Sequence		Length	Mass (Da)
	Q91XL6 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: CF0B1EA450F8E78E	FASTA	291	33,934
	10 20 30 40 50 60 QVEAMEKLIN LTDILKQEKK DETQKVQMKF LVEQMRQPDF MDALQGFLSP LNPAHQLGNL 70 80 90 100 110 120 RLEECRIMSS AKRPLWLNWE NPDIMSELLF QNNEIIFKNG DDLRQDMLTL QIIRIMENIW 130 140 150 160 170 180 QNQGLDLRML PYGCLSIGDC VGLIEVVRNS HTIMQIQCKG GLKGALQFNS HTLHQWLKDK 190 200 210 220 230 240 NKGEIYDAAI DLFTRSCAGY CVATFILGIG DRHNSNIMVK DDGQLFHIDF GHFLDHKKKK 250 260 270 280 290 FGYKRERVPF VLTQDFLIVI SKGAQEYTKT REFERFQEMC YKAYLAIRQH A

References

[1]	"Expression of phosphatidylinositol 3-kinases in rat vascular smooth muscle cells." Schaefer M., Plum C., Albrecht N., Reusch P. Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Wistar EMBL AAK83379.1. Tissue: Brain EMBL AAK83379.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF395897 mRNA. Translation: AAK83379.1.
IPI	IPI00955176.
UniGene	Rn.190480. Rn.44193.
3D structure databases
HSSP	HSSP built from PDB template 1E8Y based on UniProtKB P48736.
ProteinModelPortal	Q91XL6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q91XL6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	620916. Pik3ca.
Phylogenomic databases
eggNOG	roNOG10797.
GeneTree	ENSGT00550000074176.
HOVERGEN	HBG052721.
InParanoid	Q91XL6.
OrthoDB	EOG45TCMC.
Gene expression databases
ArrayExpress	Q91XL6.
Genevestigator	Q91XL6.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000403. PI3/4_kinase_cat. IPR018936. PI3/4_kinase_CS. IPR015433. PI_Kinase. [Graphical view]
Gene3D	G3DSA:1.10.1070.11. PI3/4_kinase_cat. 1 hit.
PANTHER	PTHR10048. PI_Kinase. 1 hit.
Pfam	PF00454. PI3_PI4_kinase. 1 hit. [Graphical view]
SMART	SM00146. PI3Kc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00915. PI3_4_KINASE_1. 1 hit. PS00916. PI3_4_KINASE_2. 1 hit. PS50290. PI3_4_KINASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q91XL6_RAT

Accession

Primary (citable) accession number: Q91XL6

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	May 31, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)