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Protein
Submitted name:

Sepiapterin reductase

Gene

Spr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1474151. Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Sepiapterin reductaseImported
Submitted name:
Sepiapterin reductase, isoform CRA_bImported
Gene namesi
Name:SprImported
ORF Names:mCG_128676Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:103078. Spr.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000033735.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1204. Eukaryota.
ENOG4111PZG. LUCA.
GeneTreeiENSGT00440000033609.
HOVERGENiHBG006973.
KOiK00072.
OMAiLVDCKVS.
OrthoDBiEOG091G0N30.
TreeFamiTF326358.

Family and domain databases

InterProiView protein in InterPro
IPR036291. NAD(P)-bd_dom_sf.
IPR002347. SDR_fam.
IPR006393. Sepiapterin_red.
PfamiView protein in Pfam
PF00106. adh_short. 1 hit.
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01500. sepiapter_red. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91XH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAGGLGCAV CVLTGASRGF GRALAPQLAR LLSPGSVMLV SARSESMLRQ
60 70 80 90 100
LKEELGAQQP DLKVVLAAAD LGTEAGVQRL LSAVRELPRP EGLQRLLLIN
110 120 130 140 150
NAATLGDVSK GFLNVNDLAE VNNYWALNLT SMLCLTSGTL NAFQDSPGLS
160 170 180 190 200
KTVVNISSLC ALQPYKGWGL YCAGKAARDM LYQVLAAEEP SVRVLSYAPG
210 220 230 240 250
PLDNDMQQLA RETSKDPELR SKLQKLKSDG ALVDCGTSAQ KLLGLLQKDT
260
FQSGAHVDFY DC
Length:262
Mass (Da):27,928
Last modified:December 1, 2001 - v1
Checksum:iE78022297439CA95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153373 Genomic DNA. No translation available.
BC010400 mRNA. Translation: AAH10400.1.
BC054423 mRNA. Translation: AAH54423.1.
CH466523 Genomic DNA. Translation: EDK99121.1.
RefSeqiNP_035597.2. NM_011467.2.
UniGeneiMm.28393.

Genome annotation databases

EnsembliENSMUST00000045986; ENSMUSP00000048111; ENSMUSG00000033735.
ENSMUST00000204757; ENSMUSP00000145412; ENSMUSG00000033735.
GeneIDi20751.
KEGGimmu:20751.
UCSCiuc012eod.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ91XH5_MOUSE
AccessioniPrimary (citable) accession number: Q91XH5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported