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Protein
Submitted name:

Sepiapterin reductase

Gene

Spr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
R-MMU-203615 eNOS activation

Names & Taxonomyi

Protein namesi
Submitted name:
Sepiapterin reductaseImported
Submitted name:
Sepiapterin reductase, isoform CRA_bImported
Gene namesi
Name:SprImported
ORF Names:mCG_128676Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:103078 Spr

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000033735

Interactioni

Protein-protein interaction databases

IntActiQ91XH5, 1 interactor

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1204 Eukaryota
ENOG4111PZG LUCA
GeneTreeiENSGT00440000033609
HOVERGENiHBG006973
KOiK00072
OMAiLVDCKVS
OrthoDBiEOG091G0N30
TreeFamiTF326358

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam
IPR006393 Sepiapterin_red
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR01500 sepiapter_red, 1 hit

Sequencei

Sequence statusi: Complete.

Q91XH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAGGLGCAV CVLTGASRGF GRALAPQLAR LLSPGSVMLV SARSESMLRQ
60 70 80 90 100
LKEELGAQQP DLKVVLAAAD LGTEAGVQRL LSAVRELPRP EGLQRLLLIN
110 120 130 140 150
NAATLGDVSK GFLNVNDLAE VNNYWALNLT SMLCLTSGTL NAFQDSPGLS
160 170 180 190 200
KTVVNISSLC ALQPYKGWGL YCAGKAARDM LYQVLAAEEP SVRVLSYAPG
210 220 230 240 250
PLDNDMQQLA RETSKDPELR SKLQKLKSDG ALVDCGTSAQ KLLGLLQKDT
260
FQSGAHVDFY DC
Length:262
Mass (Da):27,928
Last modified:December 1, 2001 - v1
Checksum:iE78022297439CA95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153373 Genomic DNA No translation available.
BC010400 mRNA Translation: AAH10400.1
BC054423 mRNA Translation: AAH54423.1
CH466523 Genomic DNA Translation: EDK99121.1
RefSeqiNP_035597.2, NM_011467.2
UniGeneiMm.28393

Genome annotation databases

EnsembliENSMUST00000045986; ENSMUSP00000048111; ENSMUSG00000033735
ENSMUST00000204757; ENSMUSP00000145412; ENSMUSG00000033735
GeneIDi20751
KEGGimmu:20751
UCSCiuc012eod.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ91XH5_MOUSE
AccessioniPrimary (citable) accession number: Q91XH5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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