Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein YIF1A

Gene

Yif1a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Possible role in transport between endoplasmic reticulum and Golgi.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIF1A
Alternative name(s):
YIP1-interacting factor homolog A
Gene namesi
Name:Yif1a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1915340. Yif1a.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini2 – 138137CytoplasmicSequence analysisAdd
BLAST
Transmembranei139 – 15921HelicalSequence analysisAdd
BLAST
Topological domaini160 – 17415ExtracellularSequence analysisAdd
BLAST
Transmembranei175 – 19521HelicalSequence analysisAdd
BLAST
Topological domaini196 – 2038CytoplasmicSequence analysis
Transmembranei204 – 22623HelicalSequence analysisAdd
BLAST
Topological domaini227 – 2293ExtracellularSequence analysis
Transmembranei230 – 24920HelicalSequence analysisAdd
BLAST
Topological domaini250 – 27122CytoplasmicSequence analysisAdd
BLAST
Transmembranei272 – 29221HelicalSequence analysisAdd
BLAST
Topological domaini293 – 2931ExtracellularSequence analysis

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 293292Protein YIF1APRO_0000233276Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei12 – 121PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ91XB7.
MaxQBiQ91XB7.
PaxDbiQ91XB7.
PRIDEiQ91XB7.

PTM databases

PhosphoSiteiQ91XB7.

Expressioni

Gene expression databases

BgeeiQ91XB7.
CleanExiMM_YIF1A.
GenevisibleiQ91XB7. MM.

Interactioni

Subunit structurei

Interacts with YIPF5.By similarity

Protein-protein interaction databases

IntActiQ91XB7. 2 interactions.
MINTiMINT-152722.
STRINGi10090.ENSMUSP00000025811.

Structurei

3D structure databases

ProteinModelPortaliQ91XB7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YIF1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3094. Eukaryota.
COG5197. LUCA.
GeneTreeiENSGT00390000009423.
HOGENOMiHOG000234333.
HOVERGENiHBG053252.
InParanoidiQ91XB7.
OMAiPYTHQCH.
OrthoDBiEOG7SXW3T.
PhylomeDBiQ91XB7.
TreeFamiTF314528.

Family and domain databases

InterProiIPR005578. Yif1_fam.
[Graphical view]
PANTHERiPTHR14083. PTHR14083. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q91XB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYHSAYGVH GSKHRTRAAP DPPPLFDDTS GGYSSQLGGY PAPGADVAFS
60 70 80 90 100
VNNLLGDPVA NMAMAYGTSI ASQGKDIVHK ELHRFVSVNK LKYFFAVDTA
110 120 130 140 150
YVAKKLGLLV FPYTHQNWKM QYSHDVPLPP RKDLNAPDLY IPTMAFITYV
160 170 180 190 200
LLAGMALGIQ QRFSPEVLGL CASTALVWVF MEVLALLLGL YLATVRSELS
210 220 230 240 250
TFHLLAYSGY KYVGMILSVL TGLLFGSDGY YVALAWTSSA LMYFIVRSLR
260 270 280 290
TAASGPDSMG GPAPRQRLQL YLTLGAAAFQ PLIIYWLTFH LVR
Length:293
Mass (Da):32,134
Last modified:December 1, 2001 - v1
Checksum:iC8FB798A9A235577
GO

Sequence cautioni

The sequence BAB21972.2 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002259 mRNA. Translation: BAB21972.2. Different initiation.
AK077329 mRNA. Translation: BAC36754.1.
AK160409 mRNA. Translation: BAE35776.1.
BC011117 mRNA. Translation: AAH11117.1.
CCDSiCCDS29450.1.
RefSeqiNP_080829.1. NM_026553.4.
UniGeneiMm.44202.

Genome annotation databases

EnsembliENSMUST00000025811; ENSMUSP00000025811; ENSMUSG00000024875.
GeneIDi68090.
KEGGimmu:68090.
UCSCiuc008gcd.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002259 mRNA. Translation: BAB21972.2. Different initiation.
AK077329 mRNA. Translation: BAC36754.1.
AK160409 mRNA. Translation: BAE35776.1.
BC011117 mRNA. Translation: AAH11117.1.
CCDSiCCDS29450.1.
RefSeqiNP_080829.1. NM_026553.4.
UniGeneiMm.44202.

3D structure databases

ProteinModelPortaliQ91XB7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ91XB7. 2 interactions.
MINTiMINT-152722.
STRINGi10090.ENSMUSP00000025811.

PTM databases

PhosphoSiteiQ91XB7.

Proteomic databases

EPDiQ91XB7.
MaxQBiQ91XB7.
PaxDbiQ91XB7.
PRIDEiQ91XB7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025811; ENSMUSP00000025811; ENSMUSG00000024875.
GeneIDi68090.
KEGGimmu:68090.
UCSCiuc008gcd.2. mouse.

Organism-specific databases

CTDi10897.
MGIiMGI:1915340. Yif1a.

Phylogenomic databases

eggNOGiKOG3094. Eukaryota.
COG5197. LUCA.
GeneTreeiENSGT00390000009423.
HOGENOMiHOG000234333.
HOVERGENiHBG053252.
InParanoidiQ91XB7.
OMAiPYTHQCH.
OrthoDBiEOG7SXW3T.
PhylomeDBiQ91XB7.
TreeFamiTF314528.

Miscellaneous databases

ChiTaRSiYif1a. mouse.
NextBioi326396.
PROiQ91XB7.
SOURCEiSearch...

Gene expression databases

BgeeiQ91XB7.
CleanExiMM_YIF1A.
GenevisibleiQ91XB7. MM.

Family and domain databases

InterProiIPR005578. Yif1_fam.
[Graphical view]
PANTHERiPTHR14083. PTHR14083. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Cerebellum and Pituitary.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Salivary gland.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Heart, Kidney, Lung, Pancreas and Testis.

Entry informationi

Entry nameiYIF1A_MOUSE
AccessioniPrimary (citable) accession number: Q91XB7
Secondary accession number(s): Q9CWB2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: December 1, 2001
Last modified: March 16, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.