Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Kelch domain-containing protein 8A

Gene

Klhdc8a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Kelch domain-containing protein 8A
Gene namesi
Name:Klhdc8a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:2442630 Klhdc8a

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002290021 – 350Kelch domain-containing protein 8AAdd BLAST350

Proteomic databases

MaxQBiQ91XA8
PaxDbiQ91XA8
PRIDEiQ91XA8

PTM databases

iPTMnetiQ91XA8
PhosphoSitePlusiQ91XA8

Expressioni

Gene expression databases

BgeeiENSMUSG00000042115
CleanExiMM_KLHDC8A
GenevisibleiQ91XA8 MM

Interactioni

Protein-protein interaction databases

BioGridi229425, 1 interactor
STRINGi10090.ENSMUSP00000038297

Structurei

3D structure databases

ProteinModelPortaliQ91XA8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1 – 31Kelch 1Add BLAST31
Repeati32 – 79Kelch 2Add BLAST48
Repeati81 – 127Kelch 3Add BLAST47
Repeati128 – 175Kelch 4Add BLAST48
Repeati176 – 222Kelch 5Add BLAST47
Repeati224 – 278Kelch 6Add BLAST55
Repeati279 – 326Kelch 7Add BLAST48

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiKOG1072 Eukaryota
ENOG4110X8D LUCA
GeneTreeiENSGT00910000144191
HOGENOMiHOG000065733
HOVERGENiHBG055245
InParanoidiQ91XA8
OMAiQQYDLRK
OrthoDBiEOG091G08A7
PhylomeDBiQ91XA8

Family and domain databases

Gene3Di2.120.10.80, 2 hits
InterProiView protein in InterPro
IPR015915 Kelch-typ_b-propeller
IPR006652 Kelch_1
PfamiView protein in Pfam
PF01344 Kelch_1, 3 hits
SMARTiView protein in SMART
SM00612 Kelch, 5 hits
SUPFAMiSSF117281 SSF117281, 2 hits

Sequencei

Sequence statusi: Complete.

Q91XA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVPNVKDFQ WKRLAPLPSR RVYCSLLETG GQVYAIGGCD DNGVPMDCFE
60 70 80 90 100
VYSPEADQWT SLPSLPTARA GVAITALGKR IMVIGGVGTN QLPVKVVEMY
110 120 130 140 150
NIDEGKWKKR SVLREAAMGI SVTAKDYRVY AAGGMGLDLR PHNYLQHYDM
160 170 180 190 200
LKDMWVSLAP MPTPRYAATS FLRGSKIYVL GGRQSKYAVN AFEVFDIESR
210 220 230 240 250
SWTKFPNIPC KRAFSSFVTL DNHLYSLGGL RQGRLYRQPK FLRTMDVFDM
260 270 280 290 300
EQGGWLKMER SFFLKKRRAD FVAGGLSGRV IVAGGLGNQP TVLETAEAFH
310 320 330 340 350
PEKNKWEALP PMPTPRCACS SIVFKNCLLA VGGVSQGLSD AVEALFVSDS
Length:350
Mass (Da):38,817
Last modified:December 1, 2001 - v1
Checksum:i92F1BC7C9870C261
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK044318 mRNA Translation: BAC31864.1
AK080356 mRNA Translation: BAC37888.1
BC011135 mRNA Translation: AAH11135.1
CCDSiCCDS35706.1
RefSeqiNP_659059.1, NM_144810.5
XP_006529417.1, XM_006529354.3
UniGeneiMm.39723

Genome annotation databases

EnsembliENSMUST00000046071; ENSMUSP00000038297; ENSMUSG00000042115
GeneIDi213417
KEGGimmu:213417
UCSCiuc007con.1 mouse

Similar proteinsi

Entry informationi

Entry nameiKLD8A_MOUSE
AccessioniPrimary (citable) accession number: Q91XA8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: December 1, 2001
Last modified: April 25, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health