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Q91XA2 (GOLM1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Golgi membrane protein 1
Alternative name(s):
Golgi membrane protein GP73
Golgi phosphoprotein 2
Gene names
Name:Golm1
Synonyms:Golph2
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Unknown. Cellular response protein to viral infection By similarity.

Subunit structure

Interacts with DYM By similarity.

Subcellular location

Golgi apparatuscis-Golgi network membrane; Single-pass type II membrane protein By similarity. Note: Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption By similarity.

Induction

Up-regulated in response to viral infection By similarity.

Post-translational modification

Phosphorylation sites are present in the extracellular medium By similarity.

Sequence similarities

Belongs to the GOLM1/CASC4 family.

Caution

It is uncertain whether Met-1 or Met-2 is the initiator.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Golgi membrane protein 1
PRO_0000087553

Regions

Topological domain1 – 1212Cytoplasmic Potential
Transmembrane13 – 3523Helical; Signal-anchor for type II membrane protein; Potential
Topological domain36 – 393358Lumenal Potential
Coiled coil40 – 183144 Potential

Amino acid modifications

Glycosylation1081N-linked (GlcNAc...); atypical Ref.4
Glycosylation1091N-linked (GlcNAc...) Ref.4
Glycosylation1441N-linked (GlcNAc...) Ref.4
Glycosylation2271N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict3191S → A in AAH11152. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q91XA2 [UniParc].

Last modified October 3, 2012. Version 2.
Checksum: B19881050CC5AD55

FASTA39344,326
        10         20         30         40         50         60 
MMGLGNGRRS MKSPPLILAA LVACVIVLGF NYWIASSRSV ELQTRIVELE GRVRRAAAER 

        70         80         90        100        110        120 
GAVELKKNEF QGELQKQREQ LDRIQSSHSF QLENVNKLHQ DEKAVLVNNI TTGEKLIRDL 

       130        140        150        160        170        180 
QDQLKALQRS YSSLQQDIFQ FQKNQTSLEK KFSYDLNQCI SQMTEVKEQC DERIEEVIRK 

       190        200        210        220        230        240 
RNEAPGSRDL AETNNQHQQA LKPQPKLQEE VPSEEQMPQE KGDVPRNKSQ IPAPNSESLG 

       250        260        270        280        290        300 
LKPQVQNEET NEIQAVGEEH QQASIQGQAV ADGTRVGAEK LDQHTQLPAG LLARPEEDSQ 

       310        320        330        340        350        360 
YPEREQLVIR DRQEQQRASE EGGGQKNPGD EYDMDENEAE SEREKQAALA GNDRNINVLN 

       370        380        390 
ADAQKRGIIN VPVGSERQSH ILNQVGIHIP QQA 

« Hide

References

[1]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[2]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Salivary gland.
[4]"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-108; ASN-109 AND ASN-144.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC134869 Genomic DNA. No translation available.
CH466546 Genomic DNA. Translation: EDL41283.1.
CH466546 Genomic DNA. Translation: EDL41284.1.
BC011152 mRNA. Translation: AAH11152.1.
CCDSCCDS26576.1.
RefSeqNP_001030294.1. NM_001035122.2.
NP_081583.3. NM_027307.4.
UniGeneMm.171335.

3D structure databases

ProteinModelPortalQ91XA2.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ91XA2.

Proteomic databases

MaxQBQ91XA2.
PaxDbQ91XA2.
PRIDEQ91XA2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000022039; ENSMUSP00000022039; ENSMUSG00000021556.
ENSMUST00000095739; ENSMUSP00000093410; ENSMUSG00000021556.
GeneID105348.
KEGGmmu:105348.
UCSCuc007quw.1. mouse.

Organism-specific databases

CTD51280.
MGIMGI:1917329. Golm1.

Phylogenomic databases

eggNOGNOG39658.
GeneTreeENSGT00530000063675.
HOGENOMHOG000065682.
HOVERGENHBG062332.
InParanoidQ91XA2.
OMAKFSYDLN.
OrthoDBEOG7992QP.
TreeFamTF331127.

Gene expression databases

CleanExMM_GOLM1.
GenevestigatorQ91XA2.

Family and domain databases

InterProIPR026143. GOLM1.
IPR026139. GOLM1/CASC4.
[Graphical view]
PANTHERPTHR15896. PTHR15896. 1 hit.
PTHR15896:SF8. PTHR15896:SF8. 1 hit.
PRINTSPR02084. GOLM1CASC4.
ProtoNetSearch...

Other

NextBio357610.
PROQ91XA2.
SOURCESearch...

Entry information

Entry nameGOLM1_MOUSE
AccessionPrimary (citable) accession number: Q91XA2
Secondary accession number(s): G3X8U4
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: October 3, 2012
Last modified: July 9, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot