##gff-version 3
Q91X84	UniProtKB	Chain	1	619	.	.	.	ID=PRO_0000318532;Note=CREB-regulated transcription coactivator 3	
Q91X84	UniProtKB	Region	129	148	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q91X84	UniProtKB	Region	375	478	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q91X84	UniProtKB	Region	380	401	.	.	.	Note=Required for interaction with PPP2CA and PPP2R1A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Compositional bias	375	390	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q91X84	UniProtKB	Compositional bias	401	439	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q91X84	UniProtKB	Compositional bias	440	456	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q91X84	UniProtKB	Compositional bias	457	478	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q91X84	UniProtKB	Modified residue	4	4	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6UUV7	
Q91X84	UniProtKB	Modified residue	62	62	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269,ECO:0007744;evidence=ECO:0000269|PubMed:28235073,ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079,PMID:28235073	
Q91X84	UniProtKB	Modified residue	160	160	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28235073;Dbxref=PMID:28235073	
Q91X84	UniProtKB	Modified residue	162	162	.	.	.	Note=Phosphoserine%3B by SIK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:28235073,ECO:0000269|PubMed:30611118;Dbxref=PMID:28235073,PMID:30611118	
Q91X84	UniProtKB	Modified residue	273	273	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:28235073,ECO:0000269|PubMed:29211348,ECO:0000269|PubMed:30611118;Dbxref=PMID:28235073,PMID:29211348,PMID:30611118	
Q91X84	UniProtKB	Modified residue	329	329	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6UUV7	
Q91X84	UniProtKB	Modified residue	332	332	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6UUV7	
Q91X84	UniProtKB	Modified residue	370	370	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
Q91X84	UniProtKB	Modified residue	391	391	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Modified residue	396	396	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Modified residue	410	410	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6UUV7	
Q91X84	UniProtKB	Modified residue	443	443	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6UUV7	
Q91X84	UniProtKB	Cross-link	232	232	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q6UUV7	
Q91X84	UniProtKB	Alternative sequence	1	299	.	.	.	ID=VSP_031221;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q91X84	UniProtKB	Mutagenesis	62	62	.	.	.	Note=Reduces interaction with 14-3-3 proteins without affecting the interaction with PPP2R1A%3B when associated with A-329 and A-370. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	162	162	.	.	.	Note=Up-regulates CREB transcription factor activity. Reduces interaction with 14-3-3 proteins. Abolishes interaction with 14-3-3 proteins without affecting the interaction with PPP2R1A%3B when associated with A-273. S->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:28235073,ECO:0000269|PubMed:30611118;Dbxref=PMID:28235073,PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	273	273	.	.	.	Note=Reduces interaction with 14-3-3 proteins. Abolishes interaction with 14-3-3 proteins without affecting the interaction with PPP2R1A%3B when associated with A-162. S->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:28235073,ECO:0000269|PubMed:30611118;Dbxref=PMID:28235073,PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	329	329	.	.	.	Note=Reduces interaction with 14-3-3 proteins without affecting the interaction with PPP2R1A%3B when associated with A-62 and A-370. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	370	370	.	.	.	Note=Reduces interaction with 14-3-3 proteins without affecting the interaction with PPP2R1A%3B when associated with A-62 and A-329. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	391	391	.	.	.	Note=Abolishes phosphorylation. Abolishes interaction with PPP2CA and PPP2R1A. Slight increase in phosphorylation at Ser-273 and in the interaction with 14-3-3 proteins. S->A%2CE;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	392	392	.	.	.	Note=Abolishes phosphorylation at Ser-391. Abolishes interaction with PPP2CA and PPP2R1A. P->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	394	394	.	.	.	Note=Does not affect phosphorylation at Ser-391 or the interaction with PPP2CA and PPP2R1A. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118	
Q91X84	UniProtKB	Mutagenesis	396	396	.	.	.	Note=Does not affect phosphorylation at Ser-391 or the interaction with PPP2CA and PPP2R1A. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30611118;Dbxref=PMID:30611118