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Q91WY5

- Q91WY5_RAT

UniProt

Q91WY5 - Q91WY5_RAT

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Protein
Submitted name:

Zinc finger transcription factor GLI3

Gene

Gli3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: Ensembl
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. anterior/posterior pattern specification Source: Ensembl
  2. anterior semicircular canal development Source: Ensembl
  3. artery development Source: Ensembl
  4. axon guidance Source: Ensembl
  5. branching involved in ureteric bud morphogenesis Source: Ensembl
  6. camera-type eye morphogenesis Source: Ensembl
  7. cell differentiation involved in kidney development Source: Ensembl
  8. cerebral cortex radial glia guided migration Source: Ensembl
  9. developmental growth Source: Ensembl
  10. embryonic digestive tract morphogenesis Source: Ensembl
  11. embryonic digit morphogenesis Source: Ensembl
  12. embryonic skeletal system morphogenesis Source: Ensembl
  13. forebrain dorsal/ventral pattern formation Source: Ensembl
  14. forebrain radial glial cell differentiation Source: Ensembl
  15. frontal suture morphogenesis Source: Ensembl
  16. heart development Source: Ensembl
  17. hindgut morphogenesis Source: Ensembl
  18. hippocampus development Source: Ensembl
  19. in utero embryonic development Source: Ensembl
  20. lambdoid suture morphogenesis Source: Ensembl
  21. lateral ganglionic eminence cell proliferation Source: Ensembl
  22. lateral semicircular canal development Source: Ensembl
  23. lung development Source: Ensembl
  24. mammary gland specification Source: Ensembl
  25. melanocyte differentiation Source: Ensembl
  26. metanephros development Source: Ensembl
  27. multicellular organismal development Source: RGD
  28. negative regulation of alpha-beta T cell differentiation Source: Ensembl
  29. negative regulation of apoptotic process Source: Ensembl
  30. negative regulation of canonical Wnt signaling pathway Source: Ensembl
  31. negative regulation of cell proliferation Source: Ensembl
  32. negative regulation of neuron differentiation Source: Ensembl
  33. negative regulation of smoothened signaling pathway Source: Ensembl
  34. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  35. negative thymic T cell selection Source: Ensembl
  36. odontogenesis of dentin-containing tooth Source: Ensembl
  37. oligodendrocyte differentiation Source: Ensembl
  38. optic nerve morphogenesis Source: Ensembl
  39. palate development Source: Ensembl
  40. positive regulation of alpha-beta T cell differentiation Source: Ensembl
  41. positive regulation of chondrocyte differentiation Source: Ensembl
  42. positive regulation of neuroblast proliferation Source: Ensembl
  43. positive regulation of osteoblast differentiation Source: Ensembl
  44. positive regulation of protein import into nucleus Source: Ensembl
  45. positive regulation of transcription, DNA-templated Source: Ensembl
  46. protein processing Source: Ensembl
  47. proximal/distal pattern formation Source: Ensembl
  48. response to estrogen Source: RGD
  49. sagittal suture morphogenesis Source: Ensembl
  50. smoothened signaling pathway Source: RGD
  51. smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
  52. smoothened signaling pathway involved in spinal cord motor neuron cell fate specification Source: Ensembl
  53. smoothened signaling pathway involved in ventral spinal cord interneuron specification Source: Ensembl
  54. thymocyte apoptotic process Source: Ensembl
  55. tongue development Source: Ensembl
  56. wound healing Source: RGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger transcription factor GLI3Imported
Gene namesi
Name:Gli3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620272. Gli3.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. mediator complex Source: Ensembl
  3. nuclear speck Source: Ensembl
  4. primary cilium Source: Ensembl
  5. transcriptional repressor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ91WY5. baseline.
GenevestigatoriQ91WY5.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019396.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG5048.

Sequencei

Sequence statusi: Fragment.

Q91WY5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AESSIAKCPT RTDVSEKAVA SSTTSNEDES AGQIYHRERR NAITMQPQSV
60 70 80 90 100
QGLSKISEEP STSSDERASL IKKEIHGSLP HLAEPSLPYR GTVFAMDPRN

GYMEPHYHP
Length:109
Mass (Da):12,011
Last modified:December 1, 2001 - v1
Checksum:i6841EDC151A7F353
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei109 – 1091Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB073718 mRNA. Translation: BAB71724.1.
UniGeneiRn.199034.

Genome annotation databases

UCSCiRGD:620272. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB073718 mRNA. Translation: BAB71724.1 .
UniGenei Rn.199034.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000019396.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi RGD:620272. rat.

Organism-specific databases

RGDi 620272. Gli3.

Phylogenomic databases

eggNOGi COG5048.

Gene expression databases

ExpressionAtlasi Q91WY5. baseline.
Genevestigatori Q91WY5.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Partial cDNA sequence amplified by RT-PCR."
    Kataoka H., Enomoto K.
    Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.
    Tissue: E18 whole embryoImported.

Entry informationi

Entry nameiQ91WY5_RAT
AccessioniPrimary (citable) accession number: Q91WY5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)