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Q91WY5

- Q91WY5_RAT

UniProt

Q91WY5 - Q91WY5_RAT

Protein
Submitted name:

Zinc finger transcription factor GLI3

Gene

Gli3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. chromatin binding Source: Ensembl
    2. sequence-specific DNA binding Source: Ensembl
    3. sequence-specific DNA binding transcription factor activity Source: Ensembl

    GO - Biological processi

    1. anterior/posterior pattern specification Source: Ensembl
    2. anterior semicircular canal development Source: Ensembl
    3. artery development Source: Ensembl
    4. axon guidance Source: Ensembl
    5. branching involved in ureteric bud morphogenesis Source: Ensembl
    6. camera-type eye morphogenesis Source: Ensembl
    7. cell differentiation involved in kidney development Source: Ensembl
    8. cerebral cortex radial glia guided migration Source: Ensembl
    9. developmental growth Source: Ensembl
    10. embryonic digestive tract morphogenesis Source: Ensembl
    11. embryonic digit morphogenesis Source: Ensembl
    12. embryonic skeletal system morphogenesis Source: Ensembl
    13. forebrain dorsal/ventral pattern formation Source: Ensembl
    14. forebrain radial glial cell differentiation Source: Ensembl
    15. frontal suture morphogenesis Source: Ensembl
    16. heart development Source: Ensembl
    17. hindgut morphogenesis Source: Ensembl
    18. in utero embryonic development Source: Ensembl
    19. lambdoid suture morphogenesis Source: Ensembl
    20. lateral ganglionic eminence cell proliferation Source: Ensembl
    21. lateral semicircular canal development Source: Ensembl
    22. lung development Source: Ensembl
    23. mammary gland specification Source: Ensembl
    24. melanocyte differentiation Source: Ensembl
    25. metanephros development Source: Ensembl
    26. multicellular organismal development Source: RGD
    27. negative regulation of alpha-beta T cell differentiation Source: Ensembl
    28. negative regulation of apoptotic process Source: Ensembl
    29. negative regulation of canonical Wnt signaling pathway Source: Ensembl
    30. negative regulation of cell proliferation Source: Ensembl
    31. negative regulation of neuron differentiation Source: Ensembl
    32. negative regulation of smoothened signaling pathway Source: Ensembl
    33. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    34. negative thymic T cell selection Source: Ensembl
    35. odontogenesis of dentin-containing tooth Source: Ensembl
    36. oligodendrocyte differentiation Source: Ensembl
    37. optic nerve morphogenesis Source: Ensembl
    38. palate development Source: Ensembl
    39. positive regulation of alpha-beta T cell differentiation Source: Ensembl
    40. positive regulation of chondrocyte differentiation Source: Ensembl
    41. positive regulation of neuroblast proliferation Source: Ensembl
    42. positive regulation of osteoblast differentiation Source: Ensembl
    43. positive regulation of protein import into nucleus Source: Ensembl
    44. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    45. protein processing Source: Ensembl
    46. proximal/distal pattern formation Source: Ensembl
    47. response to estrogen Source: RGD
    48. sagittal suture morphogenesis Source: Ensembl
    49. smoothened signaling pathway Source: RGD
    50. smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
    51. smoothened signaling pathway involved in spinal cord motor neuron cell fate specification Source: Ensembl
    52. smoothened signaling pathway involved in ventral spinal cord interneuron specification Source: Ensembl
    53. thymocyte apoptotic process Source: Ensembl
    54. tongue development Source: Ensembl
    55. wound healing Source: RGD

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Zinc finger transcription factor GLI3Imported
    Gene namesi
    Name:Gli3Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi620272. Gli3.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Ensembl
    2. mediator complex Source: Ensembl
    3. nuclear speck Source: Ensembl
    4. nucleolus Source: Ensembl
    5. primary cilium Source: Ensembl
    6. transcriptional repressor complex Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ91WY5.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000019396.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG5048.
    InParanoidiQ91WY5.

    Sequencei

    Sequence statusi: Fragment.

    Q91WY5-1 [UniParc]FASTAAdd to Basket

    « Hide

    AESSIAKCPT RTDVSEKAVA SSTTSNEDES AGQIYHRERR NAITMQPQSV    50
    QGLSKISEEP STSSDERASL IKKEIHGSLP HLAEPSLPYR GTVFAMDPRN 100
    GYMEPHYHP 109
    Length:109
    Mass (Da):12,011
    Last modified:December 1, 2001 - v1
    Checksum:i6841EDC151A7F353
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei109 – 1091Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB073718 mRNA. Translation: BAB71724.1.
    UniGeneiRn.199034.

    Genome annotation databases

    UCSCiRGD:620272. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB073718 mRNA. Translation: BAB71724.1 .
    UniGenei Rn.199034.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000019396.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi RGD:620272. rat.

    Organism-specific databases

    RGDi 620272. Gli3.

    Phylogenomic databases

    eggNOGi COG5048.
    InParanoidi Q91WY5.

    Gene expression databases

    Genevestigatori Q91WY5.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Partial cDNA sequence amplified by RT-PCR."
      Kataoka H., Enomoto K.
      Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WistarImported.
      Tissue: E18 whole embryoImported.

    Entry informationi

    Entry nameiQ91WY5_RAT
    AccessioniPrimary (citable) accession number: Q91WY5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 1, 2001
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)