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Protein

DnaJ homolog subfamily C member 9

Gene

Dnajc9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role as co-chaperone of the Hsp70 family proteins HSPA1A, HSPA1B and HSPA8.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 9
Gene namesi
Name:Dnajc9
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1915326. Dnajc9.

Subcellular locationi

  • Nucleus By similarity
  • Cytoplasm By similarity
  • Cell membrane By similarity

  • Note: Predominantly nuclear. Translocates to the cytoplasm and membrane after heat shock.By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000710641 – 259DnaJ homolog subfamily C member 9Add BLAST259

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei109PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ91WN1.
MaxQBiQ91WN1.
PaxDbiQ91WN1.
PeptideAtlasiQ91WN1.
PRIDEiQ91WN1.

2D gel databases

REPRODUCTION-2DPAGEQ91WN1.

PTM databases

iPTMnetiQ91WN1.
PhosphoSitePlusiQ91WN1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000021811.
CleanExiMM_DNAJC9.
GenevisibleiQ91WN1. MM.

Interactioni

Subunit structurei

Interacts (via J domain) with HSPA1A, HSPA1B and HSPA8.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi224364. 1 interactor.
IntActiQ91WN1. 4 interactors.
STRINGi10090.ENSMUSP00000022345.

Structurei

3D structure databases

ProteinModelPortaliQ91WN1.
SMRiQ91WN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 82JPROSITE-ProRule annotationAdd BLAST68

Phylogenomic databases

eggNOGiKOG0719. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00390000014549.
HOGENOMiHOG000165297.
HOVERGENiHBG051378.
InParanoidiQ91WN1.
KOiK09529.
OMAiYREQFEN.
OrthoDBiEOG09040HVB.
PhylomeDBiQ91WN1.
TreeFamiTF105168.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiView protein in InterPro
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiView protein in PROSITE
PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91WN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLELCEQV FGTADLYQVL GVRREASDGE VRRGYHKVSL QVHPDRVEED
60 70 80 90 100
QKEDATRRFQ ILGRVYAVLS DKEQKAVYDE QGTVDEDSAG LNQDRDWDAY
110 120 130 140 150
WRLLFKKISL EDIQAFEKTY KGSEEELNDI KQAYLDFKGD MDQIMESVLC
160 170 180 190 200
VQYTDEPRIR NIIQKAIESK EIPAYSAFVK ESKQKMNARK RRAQEEAKEA
210 220 230 240 250
ELSRKELGLE EGVDNLKALI QSRQKDRQKE MDSFLAQMEA KYCKPSKGGK

RTALKKEKK
Length:259
Mass (Da):30,059
Last modified:March 1, 2004 - v2
Checksum:iED959F4CC5B94343
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075979 mRNA. Translation: BAC36092.1.
AK077324 mRNA. Translation: BAC36750.1.
AK153033 mRNA. Translation: BAE31665.1.
AK162075 mRNA. Translation: BAE36712.1.
BC014686 mRNA. Translation: AAH14686.2.
BC023787 mRNA. Translation: AAH23787.1.
BC027012 mRNA. Translation: AAH27012.1.
CCDSiCCDS26844.1.
RefSeqiNP_598842.1. NM_134081.5.
UniGeneiMm.2871.

Genome annotation databases

EnsembliENSMUST00000022345; ENSMUSP00000022345; ENSMUSG00000021811.
GeneIDi108671.
KEGGimmu:108671.
UCSCiuc007sjn.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075979 mRNA. Translation: BAC36092.1.
AK077324 mRNA. Translation: BAC36750.1.
AK153033 mRNA. Translation: BAE31665.1.
AK162075 mRNA. Translation: BAE36712.1.
BC014686 mRNA. Translation: AAH14686.2.
BC023787 mRNA. Translation: AAH23787.1.
BC027012 mRNA. Translation: AAH27012.1.
CCDSiCCDS26844.1.
RefSeqiNP_598842.1. NM_134081.5.
UniGeneiMm.2871.

3D structure databases

ProteinModelPortaliQ91WN1.
SMRiQ91WN1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi224364. 1 interactor.
IntActiQ91WN1. 4 interactors.
STRINGi10090.ENSMUSP00000022345.

PTM databases

iPTMnetiQ91WN1.
PhosphoSitePlusiQ91WN1.

2D gel databases

REPRODUCTION-2DPAGEQ91WN1.

Proteomic databases

EPDiQ91WN1.
MaxQBiQ91WN1.
PaxDbiQ91WN1.
PeptideAtlasiQ91WN1.
PRIDEiQ91WN1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022345; ENSMUSP00000022345; ENSMUSG00000021811.
GeneIDi108671.
KEGGimmu:108671.
UCSCiuc007sjn.2. mouse.

Organism-specific databases

CTDi23234.
MGIiMGI:1915326. Dnajc9.

Phylogenomic databases

eggNOGiKOG0719. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00390000014549.
HOGENOMiHOG000165297.
HOVERGENiHBG051378.
InParanoidiQ91WN1.
KOiK09529.
OMAiYREQFEN.
OrthoDBiEOG09040HVB.
PhylomeDBiQ91WN1.
TreeFamiTF105168.

Miscellaneous databases

PROiQ91WN1.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021811.
CleanExiMM_DNAJC9.
GenevisibleiQ91WN1. MM.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiView protein in InterPro
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiView protein in PROSITE
PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDNJC9_MOUSE
AccessioniPrimary (citable) accession number: Q91WN1
Secondary accession number(s): Q3TSG3, Q8R0E3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: March 1, 2004
Last modified: February 15, 2017
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.