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Q91WD9

- SEGN_MOUSE

UniProt

Q91WD9 - SEGN_MOUSE

Protein

Secretagogin

Gene

Scgn

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Calcium bindingi25 – 36121PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi71 – 82122PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi118 – 129123PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi162 – 173124PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi210 – 221125PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi254 – 265126PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    Keywords - Ligandi

    Calcium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Secretagogin
    Gene namesi
    Name:Scgn
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:2384873. Scgn.

    Subcellular locationi

    Cytoplasm. Secreted By similarity. Cytoplasmic vesiclesecretory vesicle membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
    Note: Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions By similarity.By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell
    2. transport vesicle membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Cytoplasmic vesicle, Membrane, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 276276SecretagoginPRO_0000073637Add
    BLAST

    Proteomic databases

    MaxQBiQ91WD9.
    PRIDEiQ91WD9.

    PTM databases

    PhosphoSiteiQ91WD9.

    Expressioni

    Gene expression databases

    BgeeiQ91WD9.
    CleanExiMM_SCGN.
    GenevestigatoriQ91WD9.

    Structurei

    3D structure databases

    ProteinModelPortaliQ91WD9.
    SMRiQ91WD9. Positions 10-276.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini12 – 4736EF-hand 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini58 – 9336EF-hand 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini105 – 14036EF-hand 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini149 – 18436EF-hand 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini197 – 23236EF-hand 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini240 – 27637EF-hand 6PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 6 EF-hand domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG299305.
    GeneTreeiENSGT00390000013118.
    HOGENOMiHOG000231866.
    HOVERGENiHBG000855.
    InParanoidiQ91WD9.
    OMAiMMELVQP.
    OrthoDBiEOG71G9VB.
    PhylomeDBiQ91WD9.
    TreeFamiTF325083.

    Family and domain databases

    Gene3Di1.10.238.10. 2 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view]
    PfamiPF13202. EF-hand_5. 1 hit.
    PF13499. EF-hand_7. 1 hit.
    [Graphical view]
    SMARTiSM00054. EFh. 5 hits.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 4 hits.
    PS50222. EF_HAND_2. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q91WD9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDNARRKTPA RLDAACFWQI WQRFDKEEKG YIRETELDAF FDHLLAKSGT    50
    EDTLMEENVQ KVKEQLMTSH NVSKEGRILM KELASMFLSE DENFLLFFRL 100
    ETPLDNSVEF MQIWRKYDAD SSGFISAAEL CNFLRDLFLH HKKNISEAEL 150
    EEYTSTMMKI FDKNKDGRLD LNDLARILAL QENFLLQFKM DASSTEERKR 200
    DFEKIFAHYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL 250
    RHCDVNKDGK IQKSELALCL GLKINP 276
    Length:276
    Mass (Da):32,146
    Last modified:December 1, 2001 - v1
    Checksum:iDBC86BF7F1CF9987
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC016093 mRNA. Translation: AAH16093.1.
    CCDSiCCDS26375.1.
    RefSeqiNP_663374.1. NM_145399.1.
    UniGeneiMm.255667.

    Genome annotation databases

    EnsembliENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337.
    GeneIDi214189.
    KEGGimmu:214189.
    UCSCiuc007pvk.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC016093 mRNA. Translation: AAH16093.1 .
    CCDSi CCDS26375.1.
    RefSeqi NP_663374.1. NM_145399.1.
    UniGenei Mm.255667.

    3D structure databases

    ProteinModelPortali Q91WD9.
    SMRi Q91WD9. Positions 10-276.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q91WD9.

    Proteomic databases

    MaxQBi Q91WD9.
    PRIDEi Q91WD9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000021770 ; ENSMUSP00000021770 ; ENSMUSG00000021337 .
    GeneIDi 214189.
    KEGGi mmu:214189.
    UCSCi uc007pvk.1. mouse.

    Organism-specific databases

    CTDi 10590.
    MGIi MGI:2384873. Scgn.

    Phylogenomic databases

    eggNOGi NOG299305.
    GeneTreei ENSGT00390000013118.
    HOGENOMi HOG000231866.
    HOVERGENi HBG000855.
    InParanoidi Q91WD9.
    OMAi MMELVQP.
    OrthoDBi EOG71G9VB.
    PhylomeDBi Q91WD9.
    TreeFami TF325083.

    Miscellaneous databases

    NextBioi 374218.
    PROi Q91WD9.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q91WD9.
    CleanExi MM_SCGN.
    Genevestigatori Q91WD9.

    Family and domain databases

    Gene3Di 1.10.238.10. 2 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view ]
    Pfami PF13202. EF-hand_5. 1 hit.
    PF13499. EF-hand_7. 1 hit.
    [Graphical view ]
    SMARTi SM00054. EFh. 5 hits.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 4 hits.
    PS50222. EF_HAND_2. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Eye.

    Entry informationi

    Entry nameiSEGN_MOUSE
    AccessioniPrimary (citable) accession number: Q91WD9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 22, 2003
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3