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Protein

Secretagogin

Gene

Scgn

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi25 – 36121PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi71 – 82122PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi118 – 129123PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi162 – 173124PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi210 – 221125PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi254 – 265126PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Secretagogin
Gene namesi
Name:Scgn
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2384873. Scgn.

Subcellular locationi

Cytoplasm. Secreted By similarity. Cytoplasmic vesiclesecretory vesicle membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
Note: Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity).By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
  2. transport vesicle membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276SecretagoginPRO_0000073637Add
BLAST

Proteomic databases

MaxQBiQ91WD9.
PRIDEiQ91WD9.

PTM databases

PhosphoSiteiQ91WD9.

Expressioni

Gene expression databases

BgeeiQ91WD9.
CleanExiMM_SCGN.
GenevestigatoriQ91WD9.

Structurei

3D structure databases

ProteinModelPortaliQ91WD9.
SMRiQ91WD9. Positions 10-276.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 4736EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini58 – 9336EF-hand 2PROSITE-ProRule annotationAdd
BLAST
Domaini105 – 14036EF-hand 3PROSITE-ProRule annotationAdd
BLAST
Domaini149 – 18436EF-hand 4PROSITE-ProRule annotationAdd
BLAST
Domaini197 – 23236EF-hand 5PROSITE-ProRule annotationAdd
BLAST
Domaini240 – 27637EF-hand 6PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 6 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG299305.
GeneTreeiENSGT00390000013118.
HOGENOMiHOG000231866.
HOVERGENiHBG000855.
InParanoidiQ91WD9.
OMAiMMELVQP.
OrthoDBiEOG71G9VB.
PhylomeDBiQ91WD9.
TreeFamiTF325083.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 5 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91WD9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDNARRKTPA RLDAACFWQI WQRFDKEEKG YIRETELDAF FDHLLAKSGT
60 70 80 90 100
EDTLMEENVQ KVKEQLMTSH NVSKEGRILM KELASMFLSE DENFLLFFRL
110 120 130 140 150
ETPLDNSVEF MQIWRKYDAD SSGFISAAEL CNFLRDLFLH HKKNISEAEL
160 170 180 190 200
EEYTSTMMKI FDKNKDGRLD LNDLARILAL QENFLLQFKM DASSTEERKR
210 220 230 240 250
DFEKIFAHYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL
260 270
RHCDVNKDGK IQKSELALCL GLKINP
Length:276
Mass (Da):32,146
Last modified:December 1, 2001 - v1
Checksum:iDBC86BF7F1CF9987
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016093 mRNA. Translation: AAH16093.1.
CCDSiCCDS26375.1.
RefSeqiNP_663374.1. NM_145399.1.
UniGeneiMm.255667.

Genome annotation databases

EnsembliENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337.
GeneIDi214189.
KEGGimmu:214189.
UCSCiuc007pvk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016093 mRNA. Translation: AAH16093.1.
CCDSiCCDS26375.1.
RefSeqiNP_663374.1. NM_145399.1.
UniGeneiMm.255667.

3D structure databases

ProteinModelPortaliQ91WD9.
SMRiQ91WD9. Positions 10-276.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ91WD9.

Proteomic databases

MaxQBiQ91WD9.
PRIDEiQ91WD9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337.
GeneIDi214189.
KEGGimmu:214189.
UCSCiuc007pvk.1. mouse.

Organism-specific databases

CTDi10590.
MGIiMGI:2384873. Scgn.

Phylogenomic databases

eggNOGiNOG299305.
GeneTreeiENSGT00390000013118.
HOGENOMiHOG000231866.
HOVERGENiHBG000855.
InParanoidiQ91WD9.
OMAiMMELVQP.
OrthoDBiEOG71G9VB.
PhylomeDBiQ91WD9.
TreeFamiTF325083.

Miscellaneous databases

NextBioi374218.
PROiQ91WD9.
SOURCEiSearch...

Gene expression databases

BgeeiQ91WD9.
CleanExiMM_SCGN.
GenevestigatoriQ91WD9.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 5 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Eye.

Entry informationi

Entry nameiSEGN_MOUSE
AccessioniPrimary (citable) accession number: Q91WD9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 22, 2003
Last sequence update: December 1, 2001
Last modified: January 7, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.