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Q91WD9 (SEGN_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Secretagogin
Gene names
Name:Scgn
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cytoplasm. Secreted By similarity. Cytoplasmic vesiclesecretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Note: Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions By similarity.

Sequence similarities

Contains 6 EF-hand domains.

Ontologies

Keywords
   Cellular componentCytoplasm
Cytoplasmic vesicle
Membrane
Secreted
   DomainRepeat
   LigandCalcium
Metal-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

transport vesicle membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncalcium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Secretagogin
PRO_0000073637

Regions

Domain12 – 4736EF-hand 1
Domain58 – 9336EF-hand 2
Domain105 – 14036EF-hand 3
Domain149 – 18436EF-hand 4
Domain197 – 23236EF-hand 5
Domain240 – 27637EF-hand 6
Calcium binding25 – 36121 Potential
Calcium binding71 – 82122 Potential
Calcium binding118 – 129123 Potential
Calcium binding162 – 173124 Potential
Calcium binding210 – 221125 Potential
Calcium binding254 – 265126 Potential

Sequences

Sequence LengthMass (Da)Tools
Q91WD9 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: DBC86BF7F1CF9987

FASTA27632,146
        10         20         30         40         50         60 
MDNARRKTPA RLDAACFWQI WQRFDKEEKG YIRETELDAF FDHLLAKSGT EDTLMEENVQ 

        70         80         90        100        110        120 
KVKEQLMTSH NVSKEGRILM KELASMFLSE DENFLLFFRL ETPLDNSVEF MQIWRKYDAD 

       130        140        150        160        170        180 
SSGFISAAEL CNFLRDLFLH HKKNISEAEL EEYTSTMMKI FDKNKDGRLD LNDLARILAL 

       190        200        210        220        230        240 
QENFLLQFKM DASSTEERKR DFEKIFAHYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV 

       250        260        270 
DLDKFREILL RHCDVNKDGK IQKSELALCL GLKINP 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Eye.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC016093 mRNA. Translation: AAH16093.1.
CCDSCCDS26375.1.
RefSeqNP_663374.1. NM_145399.1.
UniGeneMm.255667.

3D structure databases

ProteinModelPortalQ91WD9.
SMRQ91WD9. Positions 10-276.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ91WD9.

Proteomic databases

MaxQBQ91WD9.
PRIDEQ91WD9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337.
GeneID214189.
KEGGmmu:214189.
UCSCuc007pvk.1. mouse.

Organism-specific databases

CTD10590.
MGIMGI:2384873. Scgn.

Phylogenomic databases

eggNOGNOG299305.
GeneTreeENSGT00390000013118.
HOGENOMHOG000231866.
HOVERGENHBG000855.
InParanoidQ91WD9.
OMAMMELVQP.
OrthoDBEOG71G9VB.
PhylomeDBQ91WD9.
TreeFamTF325083.

Gene expression databases

BgeeQ91WD9.
CleanExMM_SCGN.
GenevestigatorQ91WD9.

Family and domain databases

Gene3D1.10.238.10. 2 hits.
InterProIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamPF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTSM00054. EFh. 5 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio374218.
PROQ91WD9.
SOURCESearch...

Entry information

Entry nameSEGN_MOUSE
AccessionPrimary (citable) accession number: Q91WD9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 22, 2003
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot