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Q91WD9

- SEGN_MOUSE

UniProt

Q91WD9 - SEGN_MOUSE

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Protein

Secretagogin

Gene
Scgn
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi25 – 36121 Reviewed predictionAdd
BLAST
Calcium bindingi71 – 82122 Reviewed predictionAdd
BLAST
Calcium bindingi118 – 129123 Reviewed predictionAdd
BLAST
Calcium bindingi162 – 173124 Reviewed predictionAdd
BLAST
Calcium bindingi210 – 221125 Reviewed predictionAdd
BLAST
Calcium bindingi254 – 265126 Reviewed predictionAdd
BLAST

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Secretagogin
Gene namesi
Name:Scgn
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2384873. Scgn.

Subcellular locationi

Cytoplasm. Secreted By similarity. Cytoplasmic vesiclesecretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side By similarity
Note: Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions By similarity.

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
  2. transport vesicle membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276SecretagoginPRO_0000073637Add
BLAST

Proteomic databases

MaxQBiQ91WD9.
PRIDEiQ91WD9.

PTM databases

PhosphoSiteiQ91WD9.

Expressioni

Gene expression databases

BgeeiQ91WD9.
CleanExiMM_SCGN.
GenevestigatoriQ91WD9.

Structurei

3D structure databases

ProteinModelPortaliQ91WD9.
SMRiQ91WD9. Positions 10-276.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 4736EF-hand 1Add
BLAST
Domaini58 – 9336EF-hand 2Add
BLAST
Domaini105 – 14036EF-hand 3Add
BLAST
Domaini149 – 18436EF-hand 4Add
BLAST
Domaini197 – 23236EF-hand 5Add
BLAST
Domaini240 – 27637EF-hand 6Add
BLAST

Sequence similaritiesi

Contains 6 EF-hand domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG299305.
GeneTreeiENSGT00390000013118.
HOGENOMiHOG000231866.
HOVERGENiHBG000855.
InParanoidiQ91WD9.
OMAiMMELVQP.
OrthoDBiEOG71G9VB.
PhylomeDBiQ91WD9.
TreeFamiTF325083.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 5 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91WD9-1 [UniParc]FASTAAdd to Basket

« Hide

MDNARRKTPA RLDAACFWQI WQRFDKEEKG YIRETELDAF FDHLLAKSGT    50
EDTLMEENVQ KVKEQLMTSH NVSKEGRILM KELASMFLSE DENFLLFFRL 100
ETPLDNSVEF MQIWRKYDAD SSGFISAAEL CNFLRDLFLH HKKNISEAEL 150
EEYTSTMMKI FDKNKDGRLD LNDLARILAL QENFLLQFKM DASSTEERKR 200
DFEKIFAHYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL 250
RHCDVNKDGK IQKSELALCL GLKINP 276
Length:276
Mass (Da):32,146
Last modified:December 1, 2001 - v1
Checksum:iDBC86BF7F1CF9987
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC016093 mRNA. Translation: AAH16093.1.
CCDSiCCDS26375.1.
RefSeqiNP_663374.1. NM_145399.1.
UniGeneiMm.255667.

Genome annotation databases

EnsembliENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337.
GeneIDi214189.
KEGGimmu:214189.
UCSCiuc007pvk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC016093 mRNA. Translation: AAH16093.1 .
CCDSi CCDS26375.1.
RefSeqi NP_663374.1. NM_145399.1.
UniGenei Mm.255667.

3D structure databases

ProteinModelPortali Q91WD9.
SMRi Q91WD9. Positions 10-276.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q91WD9.

Proteomic databases

MaxQBi Q91WD9.
PRIDEi Q91WD9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000021770 ; ENSMUSP00000021770 ; ENSMUSG00000021337 .
GeneIDi 214189.
KEGGi mmu:214189.
UCSCi uc007pvk.1. mouse.

Organism-specific databases

CTDi 10590.
MGIi MGI:2384873. Scgn.

Phylogenomic databases

eggNOGi NOG299305.
GeneTreei ENSGT00390000013118.
HOGENOMi HOG000231866.
HOVERGENi HBG000855.
InParanoidi Q91WD9.
OMAi MMELVQP.
OrthoDBi EOG71G9VB.
PhylomeDBi Q91WD9.
TreeFami TF325083.

Miscellaneous databases

NextBioi 374218.
PROi Q91WD9.
SOURCEi Search...

Gene expression databases

Bgeei Q91WD9.
CleanExi MM_SCGN.
Genevestigatori Q91WD9.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view ]
Pfami PF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view ]
SMARTi SM00054. EFh. 5 hits.
[Graphical view ]
PROSITEi PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Eye.

Entry informationi

Entry nameiSEGN_MOUSE
AccessioniPrimary (citable) accession number: Q91WD9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 22, 2003
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi