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Q91WA9

- Q91WA9_MOUSE

UniProt

Q91WA9 - Q91WA9_MOUSE

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Protein
Submitted name:

ATP-binding cassette transporter ABCG4

Gene

Abcg4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATPase activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationImported, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_197984. ABCA transporters in lipid homeostasis.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette transporter ABCG4Imported
Submitted name:
ATP-binding cassette transporter White2Imported
Submitted name:
ATP-binding cassette transporter sub-family G member 4Imported
Submitted name:
ATP-binding cassette, sub-family G (WHITE), member 4Imported
Submitted name:
Protein Abcg4Imported
Submitted name:
Putative white family ABC-transporterImported
Gene namesi
Name:Abcg4Imported
Synonyms:ABCG4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1890594. Abcg4.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ91WA9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034648.

Family & Domainsi

Sequence similaritiesi

Belongs to the ABC transporter superfamily.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00740000114855.
HOVERGENiHBG103052.
KOiK05680.
OMAiCLEEHCP.
TreeFamiTF105210.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01061. ABC2_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91WA9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEKALEAVG CGLGPGAVAM AVTLEDGAEP PVLTTHLKKV ENHITEAQRF
60 70 80 90 100
SHLPKRSAVD IEFVELSYSV REGPCWRKRG YKTLLKCLSG KFCRRELIGI
110 120 130 140 150
MGPSGAGKST FMNILAGYRE SGMKGQILVN GRPRELRTFR KMSCYIMQDD
160 170 180 190 200
MLLPHLTVLE AMMVSANLKL SEKQEVKKEL VTEILTALGL MSCSHTRTAL
210 220 230 240 250
LSGGQRKRLA IALELVNNPP VMFFDEPTSG LDSASCFQVV SLMKSLAHGG
260 270 280 290 300
RTVICTIHQP SAKLFEMFDK LYILSQGQCI FKGVVTNLIP YLKGLGLHCP
310 320 330 340 350
TYHNPADFII EVASGEYGDL NPMLFRAVQN GLCTMAEKKS SPGKNELPAH
360 370 380 390 400
CPTCPPELDP IESHTFATST LTQFCILFRR TFLSILRDTV LTHLRFMSHV
410 420 430 440 450
LIGVLIGLLY LHIGDDASKV FNNTGFLFFS MLFLMFAALM PTVLTFPLEM
460 470 480 490 500
AVFMREHLNY WYTLKAYYLA KTMADVPFQV VCPVVYCSIV YWMTGQPAET
510 520 530 540 550
SRFLLFSALA IATALVAQSL GLLIGAASTS LQVATFVGPV TAIPVLLFSG
560 570 580 590 600
FFVSFKTIPT YLQWSSYLSY VRYGFEGLIL TIYGMERGHL TCLDEQCPFR
610 620 630 640
DPQIILRELD VEEAKLYMDF LVLGIFFLAL RLLAYLVLRY RVKSER
Length:646
Mass (Da):72,098
Last modified:March 1, 2004 - v2
Checksum:iED83A4C4301ED6FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124577 Genomic DNA. No translation available.
BC016200 mRNA. Translation: AAH16200.2.
AY040865 mRNA. Translation: AAK91781.1.
AF411084 mRNA. Translation: AAL57369.1.
AF378330 mRNA. Translation: AAO13805.1.
AJ426047 mRNA. Translation: CAD19779.2.
RefSeqiNP_620405.3. NM_138955.3.
UniGeneiMm.101876.

Genome annotation databases

EnsembliENSMUST00000034648; ENSMUSP00000034648; ENSMUSG00000032131.
ENSMUST00000161354; ENSMUSP00000124647; ENSMUSG00000032131.
GeneIDi192663.
KEGGimmu:192663.
UCSCiuc009pcp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124577 Genomic DNA. No translation available.
BC016200 mRNA. Translation: AAH16200.2 .
AY040865 mRNA. Translation: AAK91781.1 .
AF411084 mRNA. Translation: AAL57369.1 .
AF378330 mRNA. Translation: AAO13805.1 .
AJ426047 mRNA. Translation: CAD19779.2 .
RefSeqi NP_620405.3. NM_138955.3.
UniGenei Mm.101876.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000034648.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000034648 ; ENSMUSP00000034648 ; ENSMUSG00000032131 .
ENSMUST00000161354 ; ENSMUSP00000124647 ; ENSMUSG00000032131 .
GeneIDi 192663.
KEGGi mmu:192663.
UCSCi uc009pcp.1. mouse.

Organism-specific databases

CTDi 64137.
MGIi MGI:1890594. Abcg4.

Phylogenomic databases

GeneTreei ENSGT00740000114855.
HOVERGENi HBG103052.
KOi K05680.
OMAi CLEEHCP.
TreeFami TF105210.

Enzyme and pathway databases

Reactomei REACT_197984. ABCA transporters in lipid homeostasis.

Miscellaneous databases

ChiTaRSi Abcg4. mouse.
NextBioi 371342.
PROi Q91WA9.
SOURCEi Search...

Gene expression databases

Genevestigatori Q91WA9.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF01061. ABC2_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4."
    Annilo T., Tammur J., Hutchinson A., Rzhetsky A., Dean M., Allikmets R.
    Cytogenet. Cell Genet. 94:196-201(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Cloning and expression analysis of a novel ABC transporter, White2, that is expressed in the mouse retina."
    Kameya S., Naggert J.K., Nishina P.M.
    Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
  3. "ABCG4: a novel human white family ABC-transporter expressed in the brain and eye."
    Oldfield S., Lowry C., Ruddick J., Lightman S.
    Biochim. Biophys. Acta 1591:175-179(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: RetinaImported.
  4. "Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4."
    Yoshikawa M., Yabuuchi H., Kuroiwa A., Ikegami Y., Sai Y., Tamai I., Tsuji A., Matsuda Y., Yoshida H., Ishikawa T.
    Gene 293:67-75(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: BrainImported.
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  7. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ91WA9_MOUSE
AccessioniPrimary (citable) accession number: Q91WA9
Secondary accession number(s): Q8VBS9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: March 1, 2004
Last modified: November 26, 2014
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3