ID   UB2E2_MOUSE             Reviewed;         201 AA.
AC   Q91W82;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   16-JUN-2009, entry version 59.
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 E2;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin-protein ligase E2;
DE   AltName: Full=Ubiquitin carrier protein E2;
GN   Name=Ube2e2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Salivary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Catalyzes the covalent attachment of ubiquitin to other
CC       proteins (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + ubiquitin + protein lysine = AMP +
CC       diphosphate + protein N-ubiquityllysine.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; BC016265; AAH16265.1; -; mRNA.
DR   IPI; IPI00127440; -.
DR   RefSeq; NP_659088.1; -.
DR   UniGene; Mm.23551; -.
DR   HSSP; P15731; 1QCQ.
DR   SMR; Q91W82; 54-201.
DR   PhosphoSite; Q91W82; -.
DR   Ensembl; ENSMUSG00000058317; Mus musculus.
DR   GeneID; 218793; -.
DR   KEGG; mmu:218793; -.
DR   MGI; MGI:2384997; Ube2e2.
DR   HOGENOM; Q91W82; -.
DR   HOVERGEN; Q91W82; -.
DR   OMA; Q91W82; NASDCSA.
DR   BRENDA; 6.3.2.19; 244.
DR   NextBio; 376413; -.
DR   ArrayExpress; Q91W82; -.
DR   Bgee; Q91W82; -.
DR   GermOnline; ENSMUSG00000058317; Mus musculus.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
DR   GO; GO:0019941; P:modification-dependent protein catabolic pr...; IEA:UniProtKB-KW.
DR   GO; GO:0043687; P:post-translational protein modification; IEA:InterPro.
DR   GO; GO:0051246; P:regulation of protein metabolic process; IEA:InterPro.
DR   InterPro; IPR016135; UBQ-conjugat/RWD-like.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   Gene3D; G3DSA:3.10.110.10; UBQ-conjugat_E2; 1.
DR   Pfam; PF00179; UQ_con; 1.
DR   ProDom; PD000461; UBQ_conjugat; 1.
DR   SMART; SM00212; UBCc; 1.
DR   PROSITE; PS00183; UBIQUITIN_CONJUGAT_1; 1.
DR   PROSITE; PS50127; UBIQUITIN_CONJUGAT_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Ligase; Nucleotide-binding; Ubl conjugation pathway.
FT   CHAIN         1    201       Ubiquitin-conjugating enzyme E2 E2.
FT                                /FTId=PRO_0000082473.
FT   ACT_SITE    139    139       Glycyl thioester intermediate (By
FT                                similarity).
SQ   SEQUENCE   201 AA;  22241 MW;  445D00BECA8CD83F CRC64;
     MSTEAQRVDD SPSTSGGSSD GDQRESVQQE PDREQVQPKK KEGKISSKTA AKLSTSAKRI
     QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SPDYPFKPPK
     VTFRTRIYHC NINSQGVICL DILKDNWSPA LTISKVLLSI CSLLTDCNPA DPLVGSIATQ
     YMTNRAEHDR MARQWTKRYA T
//