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Protein

Ubiquitin-like protein 7

Gene

Ubl7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like protein 7
Gene namesi
Name:Ubl7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1916709. Ubl7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002110221 – 380Ubiquitin-like protein 7Add BLAST380

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei230PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ91W67.
MaxQBiQ91W67.
PaxDbiQ91W67.
PRIDEiQ91W67.

PTM databases

iPTMnetiQ91W67.
PhosphoSitePlusiQ91W67.

Expressioni

Gene expression databases

BgeeiENSMUSG00000055720.
GenevisibleiQ91W67. MM.

Interactioni

Subunit structurei

Binds ubiquitin.By similarity

Protein-protein interaction databases

IntActiQ91W67. 1 interactor.
MINTiMINT-4133876.
STRINGi10090.ENSMUSP00000126019.

Structurei

Secondary structure

1380
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 12Combined sources5
Beta strandi21 – 23Combined sources3
Helixi40 – 50Combined sources11
Turni52 – 54Combined sources3
Beta strandi58 – 65Combined sources8
Helixi76 – 79Combined sources4
Beta strandi86 – 93Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1X1MNMR-A1-94[»]
ProteinModelPortaliQ91W67.
SMRiQ91W67.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ91W67.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 98Ubiquitin-likePROSITE-ProRule annotationAdd BLAST81
Domaini333 – 377UBAPROSITE-ProRule annotationAdd BLAST45

Sequence similaritiesi

Contains 1 UBA domain.PROSITE-ProRule annotation
Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410KDIE. Eukaryota.
ENOG410YUJQ. LUCA.
GeneTreeiENSGT00390000015967.
HOGENOMiHOG000126817.
HOVERGENiHBG054051.
InParanoidiQ91W67.
OMAiDDFHPSA.
OrthoDBiEOG091G0II5.
PhylomeDBiQ91W67.
TreeFamiTF327176.

Family and domain databases

InterProiIPR015940. UBA.
IPR009060. UBA-like.
IPR015496. Ubiquilin.
IPR029071. Ubiquitin-rel_dom.
IPR000626. Ubiquitin_dom.
[Graphical view]
PANTHERiPTHR10677. PTHR10677. 1 hit.
PfamiPF00627. UBA. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00165. UBA. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50030. UBA. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91W67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSDWHLAV KLADQPLAPK SILQLPETEL GEYSLGGYSI SFLKQLIAGK
60 70 80 90 100
LQESVPDPEL IDLIYCGRKL KDDQTLDFYG IQPGSTVHVL RKSWPEPDQK
110 120 130 140 150
PEPVDKVAAL REFRVLHTAL HSSSSYREAV FKMLSNKESL DQIIVATPGL
160 170 180 190 200
SSDPIALGVL QDKDLFSVFA DPNMLDTLVP AHPALVNAII LVLHSVAGST
210 220 230 240 250
PMPGADSSSR SMPSSSYRDM PGGFLFDGLS DDEDDFHPST RSTPSSSTPS
260 270 280 290 300
SRPASLGYSG AAGPRPITQS ELATALALAS TPESSSHTPT PGTQGHSSGT
310 320 330 340 350
SPMSSGVQSG TPITNDLFSQ ALQHALQASG QPSLQIQWQP QLQQLRDMGI
360 370 380
QDDELSLRAL QATGGDIQAA LELIFAGGAP
Length:380
Mass (Da):40,433
Last modified:July 27, 2011 - v2
Checksum:i6DE0834A61F25820
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti35L → P in BAB26033 (PubMed:16141072).Curated1
Sequence conflicti228G → A in BAB26033 (PubMed:16141072).Curated1
Sequence conflicti331Q → H in BAB26033 (PubMed:16141072).Curated1
Sequence conflicti336I → S in AAH16456 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009025 mRNA. Translation: BAB26033.1.
AC122534 Genomic DNA. No translation available.
BC016456 mRNA. Translation: AAH16456.1.
CCDSiCCDS23234.1.
RefSeqiNP_001116345.1. NM_001122873.1.
NP_081362.2. NM_027086.3.
XP_006511469.1. XM_006511406.3.
XP_006511470.1. XM_006511407.2.
XP_006511471.1. XM_006511408.2.
UniGeneiMm.41735.

Genome annotation databases

EnsembliENSMUST00000163329; ENSMUSP00000126019; ENSMUSG00000055720.
GeneIDi69459.
KEGGimmu:69459.
UCSCiuc009pvx.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009025 mRNA. Translation: BAB26033.1.
AC122534 Genomic DNA. No translation available.
BC016456 mRNA. Translation: AAH16456.1.
CCDSiCCDS23234.1.
RefSeqiNP_001116345.1. NM_001122873.1.
NP_081362.2. NM_027086.3.
XP_006511469.1. XM_006511406.3.
XP_006511470.1. XM_006511407.2.
XP_006511471.1. XM_006511408.2.
UniGeneiMm.41735.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1X1MNMR-A1-94[»]
ProteinModelPortaliQ91W67.
SMRiQ91W67.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ91W67. 1 interactor.
MINTiMINT-4133876.
STRINGi10090.ENSMUSP00000126019.

PTM databases

iPTMnetiQ91W67.
PhosphoSitePlusiQ91W67.

Proteomic databases

EPDiQ91W67.
MaxQBiQ91W67.
PaxDbiQ91W67.
PRIDEiQ91W67.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000163329; ENSMUSP00000126019; ENSMUSG00000055720.
GeneIDi69459.
KEGGimmu:69459.
UCSCiuc009pvx.2. mouse.

Organism-specific databases

CTDi84993.
MGIiMGI:1916709. Ubl7.

Phylogenomic databases

eggNOGiENOG410KDIE. Eukaryota.
ENOG410YUJQ. LUCA.
GeneTreeiENSGT00390000015967.
HOGENOMiHOG000126817.
HOVERGENiHBG054051.
InParanoidiQ91W67.
OMAiDDFHPSA.
OrthoDBiEOG091G0II5.
PhylomeDBiQ91W67.
TreeFamiTF327176.

Miscellaneous databases

ChiTaRSiUbl7. mouse.
EvolutionaryTraceiQ91W67.
PROiQ91W67.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000055720.
GenevisibleiQ91W67. MM.

Family and domain databases

InterProiIPR015940. UBA.
IPR009060. UBA-like.
IPR015496. Ubiquilin.
IPR029071. Ubiquitin-rel_dom.
IPR000626. Ubiquitin_dom.
[Graphical view]
PANTHERiPTHR10677. PTHR10677. 1 hit.
PfamiPF00627. UBA. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00165. UBA. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50030. UBA. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUBL7_MOUSE
AccessioniPrimary (citable) accession number: Q91W67
Secondary accession number(s): E9Q1S0, Q9D7P5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: July 27, 2011
Last modified: November 2, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.