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Protein
Submitted name:

Caspase-1

Gene

Casp1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase-1Imported
Gene namesi
Name:Casp1Imported
Synonyms:ICEImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2274 Casp1

PTM / Processingi

Proteomic databases

PRIDEiQ91W32

Expressioni

Gene expression databases

GenevisibleiQ91W32 RN

Structurei

3D structure databases

ProteinModelPortaliQ91W32
SMRiQ91W32
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91CARDInterPro annotationAdd BLAST91
Domaini160 – 288CASPASE_P20InterPro annotationAdd BLAST129
Domaini315 – 400CASPASE_P10InterPro annotationAdd BLAST86

Sequence similaritiesi

Belongs to the peptidase C14A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3573 Eukaryota
ENOG410ZQIE LUCA
HOVERGENiHBG076981
KOiK01370

Family and domain databases

CDDicd00032 CASc, 1 hit
InterProiView protein in InterPro
IPR001315 CARD
IPR029030 Caspase-like_dom_sf
IPR033139 Caspase_cys_AS
IPR016129 Caspase_his_AS
IPR011029 DEATH-like_dom_sf
IPR002138 Pept_C14_p10
IPR001309 Pept_C14_p20
IPR015917 Pept_C14A
PfamiView protein in Pfam
PF00619 CARD, 1 hit
PRINTSiPR00376 IL1BCENZYME
SMARTiView protein in SMART
SM00114 CARD, 1 hit
SM00115 CASc, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52129 SSF52129, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
PS01122 CASPASE_CYS, 1 hit
PS01121 CASPASE_HIS, 1 hit
PS50207 CASPASE_P10, 1 hit
PS50208 CASPASE_P20, 1 hit

Sequencei

Sequence statusi: Complete.

Q91W32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKVLRAKR KQFINSVSVG TINGLLDELL EKRVLNQEEM DTIKLANITV
60 70 80 90 100
MEKARDLCDH VTKKGPRASQ MFITYICNED CYLAEILELQ SGPSAETVFV
110 120 130 140 150
TEDSKGGHPF SSETKEKLNK EGGAFPGPSG SLKFCPLEIA QKLWKENHSE
160 170 180 190 200
IYPIMKTPTR TRLALIICST DFQHLSRRVG ADVDLREMKL LLQDLGYTVK
210 220 230 240 250
VKENLTALEM TKELKEFAAC PEHKTSDSTF LVFMSHGLQE GICGITYSNE
260 270 280 290 300
VADILKVDTI FQMMNTLKCP SLKDKPKVII IQACRGEKQG VVLLKDSVGN
310 320 330 340 350
SEEGFLTDAI FEDDGIKKAH IEKDFIAFCS STPDNVSWRH PVRGSLFIES
360 370 380 390 400
LIKHMKEYAW SCDLEDIFRK VRFSFEQPDS RLQMPTTERV TLTKRFYLFP

GH
Length:402
Mass (Da):45,549
Last modified:December 1, 2001 - v1
Checksum:i643506242A85F170
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85899 mRNA Translation: BAB67770.1
RefSeqiNP_036894.2, NM_012762.2
UniGeneiRn.37508

Genome annotation databases

GeneIDi25166
KEGGirno:25166

Similar proteinsi

Entry informationi

Entry nameiQ91W32_RAT
AccessioniPrimary (citable) accession number: Q91W32
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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