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Q91W29 (COX42_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial
Alternative name(s):
Cytochrome c oxidase subunit IV isoform 2
Short name=COX IV-2
Gene names
Name:Cox4i2
Synonyms:Cox4b
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular location

Mitochondrion inner membrane.

Sequence similarities

Belongs to the cytochrome c oxidase IV family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 172Cytochrome c oxidase subunit 4 isoform 2, mitochondrialPRO_0000006090

Amino acid modifications

Disulfide bond41 ↔ 55 Potential

Sequences

Sequence LengthMass (Da)Tools
Q91W29 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: A2395EF4FD68CEA6

FASTA17220,206
        10         20         30         40         50         60 
MFSRAARSLV MRTGLRTRGT GTHSPGDAAG SQRRMTPYVD CYAQRSYPMP DEPFCTELSE 

        70         80         90        100        110        120 
EQRALKEKEK GSWTQLSQAE KVALYRLQFH ETFAEMNHRS NEWKTVMGCV FFFIGFTALV 

       130        140        150        160        170 
IWWQRVYVFP KKVVTLTEER KAQQLQRLLD MKSNPIQGLA AHWDYEKKEW KK 

« Hide

References

« Hide 'large scale' references
[1]"Mammalian subunit IV isoforms of cytochrome c oxidase."
Huettemann M., Kadenbach B., Grossman L.I.
Gene 267:111-123(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Heart.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF271382 mRNA. Translation: AAK49433.1.
BC049623 mRNA. Translation: AAH49623.1.
CCDSCCDS16898.1.
RefSeqNP_444321.1. NM_053091.2.
UniGeneMm.196668.

3D structure databases

ProteinModelPortalQ91W29.
SMRQ91W29. Positions 35-172.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-4997865.

Proteomic databases

PaxDbQ91W29.
PRIDEQ91W29.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000010020; ENSMUSP00000010020; ENSMUSG00000009876.
ENSMUST00000109821; ENSMUSP00000105446; ENSMUSG00000009876.
GeneID84682.
KEGGmmu:84682.
UCSCuc008ngg.1. mouse.

Organism-specific databases

CTD84701.
MGIMGI:2135755. Cox4i2.

Phylogenomic databases

eggNOGNOG328739.
GeneTreeENSGT00390000002407.
HOGENOMHOG000231486.
HOVERGENHBG051087.
InParanoidQ91W29.
KOK02263.
OMALVIWWQR.
OrthoDBEOG7BKCWF.
PhylomeDBQ91W29.
TreeFamTF105061.

Gene expression databases

BgeeQ91W29.
CleanExMM_COX4I2.
GenevestigatorQ91W29.

Family and domain databases

Gene3D1.10.442.10. 1 hit.
InterProIPR013288. Cyt_c_oxidase_su4.
IPR004203. Cyt_c_oxidase_su4_fam.
[Graphical view]
PfamPF02936. COX4. 1 hit.
[Graphical view]
PRINTSPR01873. CYTCOXIDASE4.
SUPFAMSSF81406. SSF81406. 1 hit.
ProtoNetSearch...

Other

NextBio350931.
PROQ91W29.
SOURCESearch...

Entry information

Entry nameCOX42_MOUSE
AccessionPrimary (citable) accession number: Q91W29
Entry history
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot