Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ubiquitin-associated protein 2

Gene

Ubap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-associated protein 2
Short name:
UBAP-2
Alternative name(s):
Protein lingerer homolog 1
Short name:
mLig-1
Gene namesi
Name:Ubap2Imported
Synonyms:Lig1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1916176. Ubap2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11321132Ubiquitin-associated protein 2PRO_0000270982Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei433 – 4331PhosphoserineBy similarity
Modified residuei440 – 4401PhosphoserineBy similarity
Modified residuei631 – 6311PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ91VX2.
MaxQBiQ91VX2.
PaxDbiQ91VX2.
PRIDEiQ91VX2.

PTM databases

iPTMnetiQ91VX2.
PhosphoSiteiQ91VX2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028433.
CleanExiMM_LIG1.
MM_UBAP2.
ExpressionAtlasiQ91VX2. baseline and differential.
GenevisibleiQ91VX2. MM.

Interactioni

Protein-protein interaction databases

IntActiQ91VX2. 1 interaction.
MINTiMINT-4121131.
STRINGi10090.ENSMUSP00000030143.

Structurei

3D structure databases

ProteinModelPortaliQ91VX2.
SMRiQ91VX2. Positions 28-113.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 9245UBASequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi543 – 795253Ser-richSequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 UBA domain.Sequence analysis

Phylogenomic databases

eggNOGiENOG410IGWX. Eukaryota.
ENOG4110RI8. LUCA.
GeneTreeiENSGT00390000003453.
HOGENOMiHOG000231679.
HOVERGENiHBG058387.
InParanoidiQ91VX2.
OMAiAAENHIT.
OrthoDBiEOG091G0GRY.
PhylomeDBiQ91VX2.
TreeFamiTF328468.

Family and domain databases

InterProiIPR022166. DUF3697_Uba2.
IPR015940. UBA.
IPR009060. UBA-like.
[Graphical view]
PfamiPF12478. DUF3697. 1 hit.
[Graphical view]
SMARTiSM00165. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91VX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTSVSNDRC RGAREKPQMP TAHAAQSQKQ VVQATAEQMR LAQVIFDKND
60 70 80 90 100
SDFEAKVKQL MEVTGKNQDE CIVALHDCNG DVNKAINILL EGNSDTTSWE
110 120 130 140 150
TVGGKKKNFG RESSENKENR EKRTEREASR GRGTNNRKGR GGNRVREFKG
160 170 180 190 200
EENGIDCSQG DKPAERGKRA RGRGFGRGRG RGTGRFSAQS MGTFNPADYS
210 220 230 240 250
ESMSTDGCGT KLAVWEAAQN GTDEGPEGLA KSHSMSQEPP SKSSYGLKGA
260 270 280 290 300
WKNSVEEWTT EDWTEDLSET KVFTASSAPA ENHVTPGHSI DLVALLHKPA
310 320 330 340 350
PPTQATEVNS FETSQQQGFG QALVFTNSQH NNQMAPGTAN STSASSYSPQ
360 370 380 390 400
SLSSVLGSGF GELPQSNMVN ISNSQILDKL KPPGLSPFPA ASSAQQNDTA
410 420 430 440 450
SPPATTAAWD LKPSAPQPSV LSRLDFKSQP EPSPVLSQLS QRQQHQTQAV
460 470 480 490 500
SVPPPGLESF SSLAKPREST AGDGPSTVSR LLQLPNMTVE NIVSAHQPQP
510 520 530 540 550
KHIKLPKRRV PPASKVPVSA VEMPGSSDVT GLNVQFGALE FGSEPSLSEF
560 570 580 590 600
GSAASASENS NQIPISLYPK SLSEPLNASF PMTSAVQSST YTTSVVTSST
610 620 630 640 650
LTSSALSSTS PVTTSSSYDQ SSVHTRIAYQ SSASPPDSAP GSVANGHGGG
660 670 680 690 700
RSQHTVDTTS SVPAPKKTDP SALPSVSTLP GPASCTALLP SSAQHTATLP
710 720 730 740 750
SLTPAAAELS SSPLSQLSSS LSGHQNSMTS AHATRSTSTP HTHASVESTA
760 770 780 790 800
SSAAFSAAAT SAPSAPSSGV VLPGSMSTVS SLCLGGTTVS VPSSSTRATA
810 820 830 840 850
LVTSGKAPPN LPQGVPPLLH NQYLVGPGGL LPAYPIYGYD ELQMLQSRLP
860 870 880 890 900
MDYYGIPFAA PTALASRDGN LANNPYSGDV TKFGRGDSAS PAPPTTPAQA
910 920 930 940 950
QQSQSQTHHT AQQPFLNPGL PPGYSYTGLP YYTGVPSAFQ YGPTMFVPPT
960 970 980 990 1000
SAKQHGVALS TPPTPFQQAS GYGQHAYSTG YDDLTQGTAA GDYTKGGYGG
1010 1020 1030 1040 1050
SSQAPNKSTG SGPGKGVSVS SGTGLPDMTG SVYNKTQTFD KQGFHAGTPP
1060 1070 1080 1090 1100
PFSLPSALGS TGPLAPAAAP GYAPAPFLHI MPAHQQPHSQ LLHHHLQQDA
1110 1120 1130
PSGSGQRSQP SSLQPKSQAS KPTYGSAPYW TN
Length:1,132
Mass (Da):117,966
Last modified:December 1, 2001 - v1
Checksum:iECF8E72C9134BB38
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti698 – 6981T → A in AAO23024 (PubMed:12524348).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276965 mRNA. Translation: AAO23024.1.
BC005482 mRNA. Translation: AAH05482.1.
BC007179 mRNA. Translation: AAH07179.1.
CCDSiCCDS18058.1.
RefSeqiNP_081148.1. NM_026872.1.
XP_006538287.1. XM_006538224.1.
UniGeneiMm.41864.

Genome annotation databases

EnsembliENSMUST00000030143; ENSMUSP00000030143; ENSMUSG00000028433.
GeneIDi68926.
KEGGimmu:68926.
UCSCiuc008sik.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276965 mRNA. Translation: AAO23024.1.
BC005482 mRNA. Translation: AAH05482.1.
BC007179 mRNA. Translation: AAH07179.1.
CCDSiCCDS18058.1.
RefSeqiNP_081148.1. NM_026872.1.
XP_006538287.1. XM_006538224.1.
UniGeneiMm.41864.

3D structure databases

ProteinModelPortaliQ91VX2.
SMRiQ91VX2. Positions 28-113.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ91VX2. 1 interaction.
MINTiMINT-4121131.
STRINGi10090.ENSMUSP00000030143.

PTM databases

iPTMnetiQ91VX2.
PhosphoSiteiQ91VX2.

Proteomic databases

EPDiQ91VX2.
MaxQBiQ91VX2.
PaxDbiQ91VX2.
PRIDEiQ91VX2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030143; ENSMUSP00000030143; ENSMUSG00000028433.
GeneIDi68926.
KEGGimmu:68926.
UCSCiuc008sik.1. mouse.

Organism-specific databases

CTDi55833.
MGIiMGI:1916176. Ubap2.

Phylogenomic databases

eggNOGiENOG410IGWX. Eukaryota.
ENOG4110RI8. LUCA.
GeneTreeiENSGT00390000003453.
HOGENOMiHOG000231679.
HOVERGENiHBG058387.
InParanoidiQ91VX2.
OMAiAAENHIT.
OrthoDBiEOG091G0GRY.
PhylomeDBiQ91VX2.
TreeFamiTF328468.

Miscellaneous databases

PROiQ91VX2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028433.
CleanExiMM_LIG1.
MM_UBAP2.
ExpressionAtlasiQ91VX2. baseline and differential.
GenevisibleiQ91VX2. MM.

Family and domain databases

InterProiIPR022166. DUF3697_Uba2.
IPR015940. UBA.
IPR009060. UBA-like.
[Graphical view]
PfamiPF12478. DUF3697. 1 hit.
[Graphical view]
SMARTiSM00165. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUBAP2_MOUSE
AccessioniPrimary (citable) accession number: Q91VX2
Secondary accession number(s): Q812D6, Q99K40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.