Reviewed, UniProtKB/Swiss-Prot Q91VU0 (FAM3C_MOUSE)

Names and origin

Protein names

Recommended name:
    Protein FAM3C

Gene names

Name:	Fam3c
Synonyms:	D6Wsu176e

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the FAM3 family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 227	203	Protein FAM3C		PRO_0000008753
Amino acid modifications
	Disulfide bond	58 ↔ 221		Potential
	Disulfide bond	64 ↔ 86		Potential

Sequences

	Sequence		Length	Mass (Da)
	Q91VU0-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 9195280B92838CF4	FASTA	227	24,753
	10 20 30 40 50 60 MRVAGAAKLV VAVAVFLLTF YVISQVFEIK MDASLGNLFA RSALDSAIRS TKPPRYKCGI 70 80 90 100 110 120 SKACPEKHFA FKMASGAANV VGPKICLEDN VLMSGVKNNV GRGINIALVN GKTGEVIDTK 130 140 150 160 170 180 FFDMWGGDVA PFIEFLKTIQ DGTVVLMATY DDGATKLTDE ARRLIAELGS TSITSLGFRD 190 200 210 220 NWVFCGGKGI KTKSPFEQHI KNNKETNKYE GWPEVVEMEG CIPQKQD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Mammary tumor.
[2]	Lubec G., Kang S.U. Submitted (APR-2007) to UniProtKB Cited for: PROTEIN SEQUENCE OF 73-84, MASS SPECTROMETRY. Strain: C57BL/6. Tissue: Brain.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 127-227. Strain: C57BL/6J. Tissue: Embryo.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC009086 mRNA. Translation: AAH09086.1. AK004059 mRNA. Translation: BAB23146.1.
IPI	IPI00454042.
RefSeq	NP_613053.3.
UniGene	Mm.258484
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q91VU0.
Proteomic databases
PRIDE	Q91VU0.
Genome annotation databases
Ensembl	ENSMUST00000081288; ENSMUSP00000080040; ENSMUSG00000029672; Mus musculus. [Genome view]
GeneID	27999.
KEGG	mmu:27999.
NMPDR	fig|10090.3.peg.12994.
UCSC	uc009bay.1. mouse.
Organism-specific databases
CTD	27999.
MGI	MGI:107892. Fam3c.
Phylogenomic databases
HOVERGEN	Q91VU0.
OMA	VGPKICV
OrthoDB	EOG9ZGRZC
Gene expression databases
ArrayExpress	Q91VU0.
Bgee	Q91VU0.
Genevestigator	Q91VU0.
GermOnline	ENSMUSG00000029672. Mus musculus.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	306500.
SOURCE	Search...

Entry information

Entry name

FAM3C_MOUSE

Accession

Primary (citable) accession number: Q91VU0
Secondary accession number(s): Q9CTB4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 19, 2002
Last sequence update:	December 1, 2001
Last modified:	November 24, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)