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Protein

RNA binding motif protein, X-linked-like-1

Gene

Rbmxl1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

RNA-binding protein which may be involved in pre-mRNA splicing.By similarity

GO - Molecular functioni

  • chromatin binding Source: UniProtKB
  • core promoter binding Source: UniProtKB
  • mRNA binding Source: UniProtKB
  • RNA binding Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, RNA-binding
Biological processmRNA processing, mRNA splicing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA binding motif protein, X-linked-like-1
Alternative name(s):
Heterogeneous nuclear ribonucleoprotein G-like 1
RNA binding motif protein, X chromosome retrogene
Gene namesi
Name:Rbmxl1
Synonyms:Rbmxrt
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1343045. Rbmxl1.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004080061 – 388RNA binding motif protein, X-linked-like-1Add BLAST388

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki80Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei88PhosphoserineBy similarity1
Modified residuei122Asymmetric dimethylarginine; alternateCombined sources1
Modified residuei122Omega-N-methylarginine; alternateCombined sources1
Modified residuei141Omega-N-methylarginineCombined sources1

Keywords - PTMi

Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ91VM5.
MaxQBiQ91VM5.
PaxDbiQ91VM5.
PeptideAtlasiQ91VM5.
PRIDEiQ91VM5.

PTM databases

iPTMnetiQ91VM5.
PhosphoSitePlusiQ91VM5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000037070.
GenevisibleiQ91VM5. MM.

Interactioni

Protein-protein interaction databases

BioGridi202825. 2 interactors.
IntActiQ91VM5. 4 interactors.
MINTiMINT-1868507.
STRINGi10090.ENSMUSP00000048153.

Structurei

3D structure databases

ProteinModelPortaliQ91VM5.
SMRiQ91VM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 86RRMPROSITE-ProRule annotationAdd BLAST79

Phylogenomic databases

eggNOGiENOG410IHG3. Eukaryota.
ENOG4111GI6. LUCA.
GeneTreeiENSGT00710000106295.
HOGENOMiHOG000276235.
HOVERGENiHBG063314.
InParanoidiQ91VM5.
KOiK12885.
OMAiYPDERDM.
OrthoDBiEOG091G13K0.
TreeFamiTF331833.

Family and domain databases

InterProiView protein in InterPro
IPR012604. RBM1CTR.
IPR000504. RRM_dom.
IPR003954. RRM_dom_euk.
PfamiView protein in Pfam
PF08081. RBM1CTR. 1 hit.
PF00076. RRM_1. 1 hit.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SM00361. RRM_1. 1 hit.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91VM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVEADRPGKL FIGGLNTETN EKALEAVFGK YGRIVEILLM KDRETNKSRG
60 70 80 90 100
FAFVTFESPA DAKDAARDMN GKSLDGKAIK VEQATKPSFE SGRRGPPPPP
110 120 130 140 150
RSRGPPRGLR GGSGGTRGPP SRGGYMDDGG YSMNFNMSSS RGPLPVKRGP
160 170 180 190 200
PPRSGGPPPK RSTPSGPVRS SSGMGGRTPV SRGRDSYGGP PRREPLPSRR
210 220 230 240 250
DVYLSPRDDG YSTKDSYSSR DYPSSRDTRD YAPPPRDYTY RDYSHSSSRD
260 270 280 290 300
DYPSRGYGDR DGYGRDRDYS DHPSGGSYRD SYESYGNSRS APPTRGPPPS
310 320 330 340 350
YGGSSRYDDY SSSRDGYGGS RDSYSSSRSD LYSSGRDRVG RQERGLPPSM
360 370 380
ERGYPPPRDS YSSSSRGAPR GGGRGGSRSD RGGGRSRY
Length:388
Mass (Da):42,162
Last modified:December 1, 2001 - v1
Checksum:iF4532F545E431A59
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38L → I in AAB86639 (PubMed:9457683).Curated1
Sequence conflicti56F → L in AAB86639 (PubMed:9457683).Curated1
Sequence conflicti88S → F in AAB86639 (PubMed:9457683).Curated1
Sequence conflicti232A → T in AAB86639 (PubMed:9457683).Curated1
Sequence conflicti244S → C in AAB86639 (PubMed:9457683).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF031568 mRNA. Translation: AAB86639.1.
AK041927 mRNA. Translation: BAC31099.1.
BC011441 mRNA. Translation: AAH11441.1.
BC089350 mRNA. Translation: AAH89350.1.
CCDSiCCDS22430.1.
RefSeqiNP_001239018.1. NM_001252089.1.
NP_033059.2. NM_009033.2.
XP_006530838.1. XM_006530775.2.
XP_006530839.1. XM_006530776.2.
UniGeneiMm.24718.

Genome annotation databases

EnsembliENSMUST00000049245; ENSMUSP00000048153; ENSMUSG00000037070.
ENSMUST00000211719; ENSMUSP00000147384; ENSMUSG00000037070.
GeneIDi19656.
KEGGimmu:19656.
UCSCiuc009mhz.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiRMXL1_MOUSE
AccessioniPrimary (citable) accession number: Q91VM5
Secondary accession number(s): O35479
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: December 1, 2001
Last modified: August 30, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot