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Protein

Basic leucine zipper and W2 domain-containing protein 2

Gene

Bzw2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in neuronal differentiation.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Neurogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Basic leucine zipper and W2 domain-containing protein 2
Gene namesi
Name:Bzw2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1914162 Bzw2

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002546201 – 419Basic leucine zipper and W2 domain-containing protein 2Add BLAST419

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei117N6-acetyllysineBy similarity1
Modified residuei412PhosphoserineCombined sources1
Modified residuei414PhosphoserineBy similarity1
Modified residuei419PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ91VK1
MaxQBiQ91VK1
PaxDbiQ91VK1
PeptideAtlasiQ91VK1
PRIDEiQ91VK1

PTM databases

iPTMnetiQ91VK1
PhosphoSitePlusiQ91VK1

Expressioni

Gene expression databases

BgeeiENSMUSG00000020547
ExpressionAtlasiQ91VK1 baseline and differential
GenevisibleiQ91VK1 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi211804, 2 interactors
IntActiQ91VK1, 1 interactor
STRINGi10090.ENSMUSP00000020856

Structurei

3D structure databases

ProteinModelPortaliQ91VK1
SMRiQ91VK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini248 – 415W2PROSITE-ProRule annotationAdd BLAST168

Sequence similaritiesi

Belongs to the BZW family.Curated

Phylogenomic databases

eggNOGiKOG2297 Eukaryota
ENOG410XR08 LUCA
GeneTreeiENSGT00390000012561
HOGENOMiHOG000252932
HOVERGENiHBG080940
InParanoidiQ91VK1
OMAiFMNKHQK
OrthoDBiEOG091G090E
PhylomeDBiQ91VK1
TreeFamiTF324313

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR016021 MIF4-like_sf
IPR003307 W2_domain
PfamiView protein in Pfam
PF02020 W2, 1 hit
SMARTiView protein in SMART
SM00515 eIF5C, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51363 W2, 1 hit

Sequencei

Sequence statusi: Complete.

Q91VK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK
60 70 80 90 100
FLDSTGSRLD YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS
110 120 130 140 150
ANEDHETIRN YAQVFNKLIR RYKYLEKAFE DEMKKLLLFL KAFSEAEQTK
160 170 180 190 200
LAMLSGILLG NGTLPATILT SLFTDSLVKE GIAASFAVKL FKAWMAEKDA
210 220 230 240 250
NSVTSSLRKA NLDKRLLELF PVNRQSVDHF AKYFTDAGLK ELSDFLRVQQ
260 270 280 290 300
SLGTRKELQK ELQERLSQEC PIKEVVLYVK EEMKRNDLPE TAVIGLLWTC
310 320 330 340 350
IMNAVEWNKK EELVAEQALK HLKQYAPLLA VFSSQGQSEL VLLQKVQEYC
360 370 380 390 400
YDNIHFMKAF QKIVVLFYKA DVLSEEAILK WYKEAHAAKG KSVFLDQMKK
410
FVEWLQNAEE ESESEGEES
Length:419
Mass (Da):48,063
Last modified:December 1, 2001 - v1
Checksum:i996FC462B50EAF6F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti69F → L in BAB27495 (PubMed:16141072).Curated1
Sequence conflicti326A → R in BAB27495 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK011253 mRNA Translation: BAB27495.1
AK160544 mRNA Translation: BAE35861.1
BC013060 mRNA Translation: AAH13060.1
CCDSiCCDS25884.1
RefSeqiNP_080116.2, NM_025840.3
UniGeneiMm.288669

Genome annotation databases

EnsembliENSMUST00000020856; ENSMUSP00000020856; ENSMUSG00000020547
GeneIDi66912
KEGGimmu:66912
UCSCiuc007njp.2 mouse

Similar proteinsi

Entry informationi

Entry nameiBZW2_MOUSE
AccessioniPrimary (citable) accession number: Q91VK1
Secondary accession number(s): Q9D0N4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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