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Protein
Submitted name:

Sbf2 protein

Gene

Sbf2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • phosphatase binding Source: MGI
  • phosphatase regulator activity Source: MGI
  • phosphatidylinositol binding Source: MGI
  • protein homodimerization activity Source: MGI
  • Rab guanyl-nucleotide exchange factor activity Source: MGI

GO - Biological processi

  • protein tetramerization Source: MGI

Names & Taxonomyi

Protein namesi
Submitted name:
Sbf2 proteinImported
Gene namesi
Name:Sbf2Imported
Synonyms:Mtmr13Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1921831. Sbf2.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: MGI
  • vacuolar membrane Source: MGI

PTM / Processingi

Proteomic databases

PaxDbiQ91VH0.
PeptideAtlasiQ91VH0.

Interactioni

GO - Molecular functioni

  • phosphatase binding Source: MGI
  • protein homodimerization activity Source: MGI

Protein-protein interaction databases

IntActiQ91VH0. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ91VH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 565Myotubularin phosphataseInterPro annotationAdd BLAST477
Domaini724 – 828PHInterPro annotationAdd BLAST105

Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.SAAS annotation

Phylogenomic databases

eggNOGiKOG1090. Eukaryota.
KOG4471. Eukaryota.
ENOG410XTJ1. LUCA.
HOGENOMiHOG000044360.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR030567. MTMR13.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR029021. Prot-tyrosine_phosphatase-like.
PANTHERiPTHR10807. PTHR10807. 1 hit.
PTHR10807:SF106. PTHR10807:SF106. 1 hit.
PfamiView protein in Pfam
PF06602. Myotub-related. 1 hit.
PF00169. PH. 1 hit.
SMARTiView protein in SMART
SM00233. PH. 1 hit.
SUPFAMiSSF50729. SSF50729. 2 hits.
SSF52799. SSF52799. 2 hits.
PROSITEiView protein in PROSITE
PS50003. PH_DOMAIN. 1 hit.
PS51339. PPASE_MYOTUBULARIN. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q91VH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HASEIILPKQ KEKNTSFRTF SKTIVKGAKK AGKMTIGRQY LLKKRTGTIV
60 70 80 90 100
EERVNRPGWN EEDDISVSDD SELPTSTTLK ASEKSTMEQL VEKACFRDYQ
110 120 130 140 150
RLGLGTISGN SSRSKPEYFR VTASNRLYSL CRSYPGLLVI PQAVQDSSLP
160 170 180 190 200
RVARCYRHNR LPVVCWKNSR SGTLLLRSGG FHGKGVVGLF KSQNSPQAVS
210 220 230 240 250
TSSLESSSSI EQEKYLQALL TAVIVHQKLR GSSTLTVRPA LALSPGVWAS
260 270 280 290 300
LRSSTRLISS PTSFIDVGAR LAGKDHSASF SNSTYLQNQL LKRQAALYIF
310 320 330 340 350
GEKSQLRSSK VEFAFNCEFV PVEFHEIRQV KASFKKLMRA CIPSTIPTDS
360 370 380 390 400
EVTFLKALGD SEWFPQLHRI MQLAVVVSEV LENGSSVWVC LEEGWDITTQ
410 420 430 440 450
VTSLAQLLSD PFYRTIAGFR TLVEKEWLSF GHKFSQRSSL ALNSQGGGFA
460 470 480 490 500
PIFFQFLDCV HQVHNQYPTE FEFNLYYLKF LAFHYVSNRF KTFLLDSDYE
510 520 530 540 550
RLEHGTLFDD KGDKHAKKGV CIWECIDKMH TRSPIFFNYL YSPVEVEALK
560 570 580 590 600
PNVNVSSLKK WDYYTEETLS AGPSYDWMML TPKHFPYEES DVAGGAGPQS
610 620 630 640 650
QRKTVWPCYD DVTCSQPDAL TRLFSEIEKL EHKLNQTPER WHQLWEKVTT
660 670 680 690 700
DLKEEPRTAH SLRHSAGSPG IASTNVPSYQ KRPALHPLHR GLGEDQSTTT
710 720 730 740 750
APSNGVEHRA ATLYSQYTSK NDENRSFEGT LYKRGALLKG WKPRWFVLDV
760 770 780 790 800
TKHQLRYYDS GEDTSCKGHI DLAEVEMVIP AGPSMGAPKY TSDKAFFDLK
810 820 830
TSKRVYNFCA QDGQSAQQWM DRIQSCISDA
Length:830
Mass (Da):93,823
Last modified:December 1, 2001 - v1
Checksum:i234DA0F5B28D76E4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC015069 mRNA. Translation: AAH15069.1.
UniGeneiMm.102970.

Genome annotation databases

UCSCiuc012fsf.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ91VH0_MOUSE
AccessioniPrimary (citable) accession number: Q91VH0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 5, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)