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Protein
Submitted name:

Prostaglandin E receptor 4 (Subtype EP4), isoform CRA_b

Gene

Ptger4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin E receptor 4 (Subtype EP4), isoform CRA_bImported
Submitted name:
Prostaglandin E2 receptor EP4 subtypeImported
Submitted name:
Ptger4 proteinImported
Gene namesi
Name:Ptger4Imported
ORF Names:mCG_10988Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:104311. Ptger4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4222HelicalSequence analysisAdd
BLAST
Transmembranei54 – 7724HelicalSequence analysisAdd
BLAST
Transmembranei97 – 11519HelicalSequence analysisAdd
BLAST
Transmembranei135 – 15622HelicalSequence analysisAdd
BLAST
Transmembranei186 – 21126HelicalSequence analysisAdd
BLAST
Transmembranei274 – 29724HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000039942.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000048736.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 332299G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119188.
HOGENOMiHOG000251595.
HOVERGENiHBG053556.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001758. Prost_EP4_rcpt.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 2 hits.
PTHR11866:SF6. PTHR11866:SF6. 2 hits.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00586. PRSTNOIDEP4R.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91VE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIPGVNASF SSTPERLNSP VTIPAVMFIF GVVGNLVAIV VLCKSRKEQK
60 70 80 90 100
ETTFYTLVCG LAVTDLLGTL LVSPVTIATY MKGQWPGDQA LCDYSTFILL
110 120 130 140 150
FFGLSGLSII CAMSIERYLA INHAYFYSHY VDKRLAGLTL FAIYASNVLF
160 170 180 190 200
CALPNMGLGR SERQYPGTWC FIDWTTNVTA YAAFSYMYAG FSSFLILATV
210 220 230 240 250
LCNVLVCGAL LRMHRQFMRR TSLGTEQHHA AAAAAVASVA CRGHAGASPA
260 270 280 290 300
LQRLSDFRRR RSFRRIAGAE IQMVILLIAT SLVVLICSIP LVVRVFINQL
310 320 330 340 350
YQPNVVKDIS RNPDLQAIRI ASVNPILDPW IYILLRKTVL SKAIEKIKCL
360 370 380 390 400
FCRIGGSGRD SSAQHCSESR RTSSAMSGHS RSFLARELKE ISSTSQTLLY
410 420 430 440 450
LPDLTESSLG GRNLLPGSHG MGLTQADTTS LRTLRISETS DSSQGQDSES
460 470 480
VLLVDEVSGS HREEPASKGN SLQVTFPSET LKLSEKCI
Length:488
Mass (Da):53,417
Last modified:December 1, 2001 - v1
Checksum:i0D4B48127283A5B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135079 Genomic DNA. No translation available.
BC009023 mRNA. Translation: AAH09023.1.
BC011193 mRNA. Translation: AAH11193.1.
CH466581 Genomic DNA. Translation: EDL03377.1.
RefSeqiNP_001129551.1. NM_001136079.2.
UniGeneiMm.18509.

Genome annotation databases

EnsembliENSMUST00000120563; ENSMUSP00000112858; ENSMUSG00000039942.
GeneIDi19219.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135079 Genomic DNA. No translation available.
BC009023 mRNA. Translation: AAH09023.1.
BC011193 mRNA. Translation: AAH11193.1.
CH466581 Genomic DNA. Translation: EDL03377.1.
RefSeqiNP_001129551.1. NM_001136079.2.
UniGeneiMm.18509.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000048736.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000120563; ENSMUSP00000112858; ENSMUSG00000039942.
GeneIDi19219.

Organism-specific databases

CTDi5734.
MGIiMGI:104311. Ptger4.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119188.
HOGENOMiHOG000251595.
HOVERGENiHBG053556.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039942.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001758. Prost_EP4_rcpt.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 2 hits.
PTHR11866:SF6. PTHR11866:SF6. 2 hits.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00586. PRSTNOIDEP4R.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ91VE4_MOUSE
AccessioniPrimary (citable) accession number: Q91VE4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.