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Q91VD8

- Q91VD8_MOUSE

UniProt

Q91VD8 - Q91VD8_MOUSE

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Protein
Submitted name:

MCG141290

Gene

Pcdhb17

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.SAAS annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro

GO - Biological processi

  1. homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotation

Keywords - Ligandi

CalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MCG141290Imported
Submitted name:
Protein Pcdhb17Imported
Submitted name:
Protocadherin beta 17Imported
Gene namesi
Name:Pcdhb17Imported
ORF Names:mCG_141290Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:2136754. Pcdhb17.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ91VD8.

Interactioni

Protein-protein interaction databases

DIPiDIP-59561N.
STRINGi10090.ENSMUSP00000055072.

Family & Domainsi

Sequence similaritiesi

Contains cadherin domains.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118847.
HOVERGENiHBG054878.
KOiK16494.
OMAiEHNITVQ.
OrthoDBiEOG7KSX80.
TreeFamiTF332299.

Family and domain databases

Gene3Di2.60.40.60. 5 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR010221. VCBS_rpt.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
TIGRFAMsiTIGR01965. VCBS_repeat. 1 hit.
PROSITEiPS00232. CADHERIN_1. 4 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91VD8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
METAWMCNLR QRQVLAFFVL LHVSGAGAEL GPYSIEEETE RGSFVANLGK
60 70 80 90 100
DLGVDLAEIS NRRARIISQE NKEHLQLNLQ SGDLLINEKL DREELCGPIE
110 120 130 140 150
PCVLHFQVLM ENPLEVFQAE LRVMDINDYS PVFSEREMIL RILENSALGD
160 170 180 190 200
TFPLNNALDS DVAINNIQTY RLSSNSHFLV VTRNRSDGRK YPELVLEKEL
210 220 230 240 250
DREEEPELRL TLTALDGGAP PRSGTAQVLI EVVDINDNAP KFQQPTYRVQ
260 270 280 290 300
IPENSPTGSL VLTVSANDLD SGDYGKVLYA LSQPSEDISK TLEVNPVTGE
310 320 330 340 350
IRLRKEVDFE TIPSYEVDIK ATDGGGLSGK CTLLLKVVDV NDNAPEVMLS
360 370 380 390 400
ALTSPVPENS PDEVVAVFSV KDPDSANNGK MIASIEEDLP FLLKSSGKNF
410 420 430 440 450
YTLVTKRALD REEREKYNIT ITVSDLGTPR LTTQHTITVQ VSDTNDNAPA
460 470 480 490 500
FNQTSYTLFV RENNSPAMHI GTISATDSDA GSNSHISYSL LPSHDPQLAL
510 520 530 540 550
DSLISINADN GQLFALRALD YEALQAFEFH VGAIDQGSPA LSSQALVRVV
560 570 580 590 600
VLDDNDNAPF VLYPMQNSSA PCTELLPRAA EPGYLVTKVV AVDRDSGQNA
610 620 630 640 650
WLSFQLLKAT EPGLFSVWAH NGEVRTTRLL SERDVPKHRL VLLVKDNGDP
660 670 680 690 700
PRSASVTLHV LVVDGFSQPY LPLPEVARNP AHDEDALTLY LVIALASVSS
710 720 730 740 750
LFLLSVLLFV GVRLCRRARS ASLSGYSVPE GHIPGHLVDV RGVGTLSQSY
760 770 780 790
QYDVCLMGDS SGTSEFNFLK PVFPSSLDQC SGKEIEENSS LHNSFGFHH
Length:799
Mass (Da):87,744
Last modified:December 1, 2001 - v1
Checksum:i13807F0927972952
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA. No translation available.
BC017149 mRNA. Translation: AAH17149.1.
AY013778 mRNA. Translation: AAK26067.1.
AK077255 mRNA. Translation: BAC36711.1.
CH466528 Genomic DNA. Translation: EDL10154.1.
RefSeqiNP_444372.2. NM_053142.3.
UniGeneiMm.87553.

Genome annotation databases

EnsembliENSMUST00000053856; ENSMUSP00000055072; ENSMUSG00000046387.
GeneIDi93888.
KEGGimmu:93888.
UCSCiuc008eqc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA. No translation available.
BC017149 mRNA. Translation: AAH17149.1 .
AY013778 mRNA. Translation: AAK26067.1 .
AK077255 mRNA. Translation: BAC36711.1 .
CH466528 Genomic DNA. Translation: EDL10154.1 .
RefSeqi NP_444372.2. NM_053142.3.
UniGenei Mm.87553.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-59561N.
STRINGi 10090.ENSMUSP00000055072.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000053856 ; ENSMUSP00000055072 ; ENSMUSG00000046387 .
GeneIDi 93888.
KEGGi mmu:93888.
UCSCi uc008eqc.1. mouse.

Organism-specific databases

CTDi 54661.
MGIi MGI:2136754. Pcdhb17.

Phylogenomic databases

GeneTreei ENSGT00760000118847.
HOVERGENi HBG054878.
KOi K16494.
OMAi EHNITVQ.
OrthoDBi EOG7KSX80.
TreeFami TF332299.

Miscellaneous databases

NextBioi 351821.
PROi Q91VD8.
SOURCEi Search...

Gene expression databases

Genevestigatori Q91VD8.

Family and domain databases

Gene3Di 2.60.40.60. 5 hits.
InterProi IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR010221. VCBS_rpt.
[Graphical view ]
Pfami PF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view ]
PRINTSi PR00205. CADHERIN.
SMARTi SM00112. CA. 5 hits.
[Graphical view ]
SUPFAMi SSF49313. SSF49313. 5 hits.
TIGRFAMsi TIGR01965. VCBS_repeat. 1 hit.
PROSITEi PS00232. CADHERIN_1. 4 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A striking organization of a large family of human neural cadherin-like cell adhesion genes."
    Wu Q., Maniatis T.
    Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  2. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  3. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  5. "Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
    Wu Q., Maniatis T.
    Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  6. "Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."
    Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M., Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.
    Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  7. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  8. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  9. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  11. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.
  12. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  13. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  14. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  15. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  16. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ91VD8_MOUSE
AccessioniPrimary (citable) accession number: Q91VD8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 26, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3