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Q91VB8 (Q91VB8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 123. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Alpha globin 2 EMBL AAL32372.1

Alpha-globin EMBL ABU54054.1

Hemoglobin alpha, adult chain 1 EMBL AAH43020.1

Hemoglobin subunit alpha Ensembl ENSMUSP00000090897

Protein Hba-a2 Ensembl ENSMUSP00000090895
Gene names
Name:haemaglobin alpha 1 EMBL AAL32371.1
Synonyms:haemaglobin alpha 2 EMBL AAL32372.1, Hba-a1 EMBL AAH43020.1 Ensembl ENSMUSP00000090897, Hba-a2 Ensembl ENSMUSP00000090895
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length142 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the globin family. RuleBase RU000356

Sequences

Sequence LengthMass (Da)Tools
Q91VB8 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 2F6A3712E555CB4A

FASTA14215,112
        10         20         30         40         50         60 
MVLSGEDKSN IKAAWGKIGG HGAEYGAEAL ERMFASFPTT KTYFPHFDVS HGSAQVKGHG 

        70         80         90        100        110        120 
KKVADALANA AGHLDDLPGA LSALSDLHAH KLRVDPVNFK LLSHCLLVTL ASHHPADFTP 

       130        140 
AVHASLDKFL ASVSTVLTSK YR 

« Hide

References

« Hide 'large scale' references
[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[4]Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. expand/collapse author list , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB22552.1.
Tissue: Liver EMBL BAB27269.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[5]Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. expand/collapse author list , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y.
Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1.
Tissue: Liver EMBL BAB31564.1.
[6]"Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster."
Flint J., Tufarelli C., Peden J., Clark K., Daniels R.J., Hardison R., Miller W., Philipsen S., Tan-Un K.C., McMorrow T., Frampton J., Alter B.P., Frischauf A.-M., Higgs D.R.
Hum. Mol. Genet. 10:371-382(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[7]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[8]Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. expand/collapse author list , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25790.1.
Tissue: Liver EMBL BAC25790.1.
[9]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[10]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6 EMBL AAH43020.1.
Tissue: Brain EMBL AAH43020.1.
[11]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1.
[12]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[13]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB31564.1 and NOD EMBL BAE42724.1.
Tissue: Activated spleen EMBL BAE42724.1, Liver EMBL BAB31564.1, Placenta EMBL BAB24028.1, Spleen EMBL BAB22552.1 and Whole body EMBL BAB28166.1.
[14]"Complex signatures of selection and gene conversion in the duplicated globin genes of house mice."
Storz J.F., Baze M., Waite J.L., Hoffmann F.G., Opazo J.C., Hayes J.P.
Genetics 177:481-500(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Lima_127 EMBL ABU54054.1.
[15]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000090897 Ensembl ENSMUSP00000090895.
[16]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000090897 Ensembl ENSMUSP00000090895.
[17]"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL662780 Genomic DNA. No translation available.
BC043020 mRNA. Translation: AAH43020.1.
AY016021 Genomic DNA. Translation: AAL32371.1.
AY016021 Genomic DNA. Translation: AAL32372.1.
EF605472 Genomic DNA. Translation: ABU54054.1.
AK003077 mRNA. Translation: BAB22552.1.
AK005434 mRNA. Translation: BAB24028.1.
AK010923 mRNA. Translation: BAB27269.1.
AK010927 mRNA. Translation: BAB27272.1.
AK010933 mRNA. Translation: BAB27277.1.
AK010937 mRNA. Translation: BAB27279.1.
AK010987 mRNA. Translation: BAB27307.1.
AK011018 mRNA. Translation: BAB27336.1.
AK011023 mRNA. Translation: BAB27340.1.
AK011025 mRNA. Translation: BAB27342.1.
AK011028 mRNA. Translation: BAB27344.1.
AK011030 mRNA. Translation: BAB27346.1.
AK011055 mRNA. Translation: BAB27364.1.
AK011073 mRNA. Translation: BAB27378.1.
AK011121 mRNA. Translation: BAB27414.1.
AK012329 mRNA. Translation: BAB28166.1.
AK012348 mRNA. Translation: BAB28179.1.
AK012755 mRNA. Translation: BAB28446.1.
AK019138 mRNA. Translation: BAB31564.1.
AK028173 mRNA. Translation: BAC25790.1.
AK171893 mRNA. Translation: BAE42724.1.
RefSeqNP_001077424.1. NM_001083955.1.
NP_032244.2. NM_008218.2.
UniGeneMm.196110.
Mm.459653.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

DNASU110257.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000093207; ENSMUSP00000090895; ENSMUSG00000069917.
ENSMUST00000093209; ENSMUSP00000090897; ENSMUSG00000069919.
GeneID110257.
15122.
KEGGmmu:110257.
mmu:15122.
UCSCuc007ijk.1. mouse.

Organism-specific databases

CTD110257.
15122.
MGIMGI:96015. Hba-a1.
MGI:96016. Hba-a2.

Phylogenomic databases

GeneTreeENSGT00740000115388.
HOVERGENHBG009709.
InParanoidQ91VB8.
KOK13822.
OMADKFLCAV.
OrthoDBEOG7KH9MP.
TreeFamTF332328.

Gene expression databases

GenevestigatorQ91VB8.

Family and domain databases

Gene3D1.10.490.10. 1 hit.
InterProIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
IPR002338. Haemoglobin_a.
IPR002339. Haemoglobin_pi.
[Graphical view]
PfamPF00042. Globin. 1 hit.
[Graphical view]
PRINTSPR00612. ALPHAHAEM.
PR00815. PIHAEM.
SUPFAMSSF46458. SSF46458. 1 hit.
PROSITEPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio287546.
PROQ91VB8.
SOURCESearch...

Entry information

Entry nameQ91VB8_MOUSE
AccessionPrimary (citable) accession number: Q91VB8
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)