Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q91VB3 (PRM2_RATTU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 3, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protamine-2
Alternative name(s):
Sperm histone P2
Sperm protamine P2
Gene names
Name:Prm2
OrganismRattus tunneyi (Tunney's rat) (Pale field rat)
Taxonomic identifier10121 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length105 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

Subcellular location

Nucleus. Chromosome.

Tissue specificity

Testis.

Sequence similarities

Belongs to the protamine P2 family.

Ontologies

Keywords
   Biological processDifferentiation
DNA condensation
Spermatogenesis
   Cellular componentChromosome
Nucleosome core
Nucleus
   LigandDNA-binding
   Molecular functionDevelopmental protein
Gene Ontology (GO)
   Biological_processcell differentiation

Inferred from electronic annotation. Source: UniProtKB-KW

chromosome condensation

Inferred from electronic annotation. Source: UniProtKB-KW

multicellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

spermatogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleosome

Inferred from electronic annotation. Source: UniProtKB-KW

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 105105Protamine-2
PRO_0000254959

Sequences

Sequence LengthMass (Da)Tools
Q91VB3 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 390B5B50A5F0911F

FASTA10513,328
        10         20         30         40         50         60 
MVRYRMRSPS ESPHQGPGQD HESEEQGQGQ ELNPERVEDY GRTHRGHHRH RRCSRKRLHR 

        70         80         90        100 
IHKRRRSCRR RRRHSCCHRR RHRRGCRRSR RRRRCRCRKC RRQCH 

« Hide

References

[1]"Variable regulation of protamine 2 gene expression in muroid rodents."
Dolan C.E., Fabes S.E., Mazrimas J.A., Corzett M.H., Breed W.G., Balhorn R.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF268199 Genomic DNA. Translation: AAK98518.1.
AF268200 mRNA. Translation: AAK98519.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR000492. Protamine_P2.
[Graphical view]
PANTHERPTHR21341. PTHR21341. 1 hit.
PfamPF00841. Protamine_P2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePRM2_RATTU
AccessionPrimary (citable) accession number: Q91VB3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 1, 2001
Last modified: October 3, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families