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Q91VB3

- PRM2_RATTU

UniProt

Q91VB3 - PRM2_RATTU

Protein

Protamine-2

Gene

Prm2

Organism
Rattus tunneyi (Tunney's rat) (Pale field rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. chromosome condensation Source: UniProtKB-KW
    3. multicellular organismal development Source: UniProtKB-KW
    4. spermatogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, DNA condensation, Spermatogenesis

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protamine-2
    Alternative name(s):
    Sperm histone P2
    Sperm protamine P2
    Gene namesi
    Name:Prm2
    OrganismiRattus tunneyi (Tunney's rat) (Pale field rat)
    Taxonomic identifieri10121 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Subcellular locationi

    GO - Cellular componenti

    1. nucleosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chromosome, Nucleosome core, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 105105Protamine-2PRO_0000254959Add
    BLAST

    Expressioni

    Tissue specificityi

    Testis.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the protamine P2 family.Curated

    Family and domain databases

    InterProiIPR000492. Protamine_P2.
    [Graphical view]
    PANTHERiPTHR21341. PTHR21341. 1 hit.
    PfamiPF00841. Protamine_P2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q91VB3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVRYRMRSPS ESPHQGPGQD HESEEQGQGQ ELNPERVEDY GRTHRGHHRH    50
    RRCSRKRLHR IHKRRRSCRR RRRHSCCHRR RHRRGCRRSR RRRRCRCRKC 100
    RRQCH 105
    Length:105
    Mass (Da):13,328
    Last modified:December 1, 2001 - v1
    Checksum:i390B5B50A5F0911F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF268199 Genomic DNA. Translation: AAK98518.1.
    AF268200 mRNA. Translation: AAK98519.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF268199 Genomic DNA. Translation: AAK98518.1 .
    AF268200 mRNA. Translation: AAK98519.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR000492. Protamine_P2.
    [Graphical view ]
    PANTHERi PTHR21341. PTHR21341. 1 hit.
    Pfami PF00841. Protamine_P2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Variable regulation of protamine 2 gene expression in muroid rodents."
      Dolan C.E., Fabes S.E., Mazrimas J.A., Corzett M.H., Breed W.G., Balhorn R.
      Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].

    Entry informationi

    Entry nameiPRM2_RATTU
    AccessioniPrimary (citable) accession number: Q91VB3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3