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Protein

Polymerase delta-interacting protein 2

Gene

Poldip2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • mitochondrion morphogenesis Source: MGI
  • negative regulation of macroautophagy Source: MGI
  • positive regulation of mitotic cell cycle Source: MGI

Names & Taxonomyi

Protein namesi
Recommended name:
Polymerase delta-interacting protein 2
Gene namesi
Name:Poldip2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1915061 Poldip2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001979761 – 368Polymerase delta-interacting protein 2Add BLAST368

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei292PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ91VA6
MaxQBiQ91VA6
PaxDbiQ91VA6
PeptideAtlasiQ91VA6
PRIDEiQ91VA6

PTM databases

iPTMnetiQ91VA6
PhosphoSitePlusiQ91VA6

Expressioni

Gene expression databases

BgeeiENSMUSG00000001100
ExpressionAtlasiQ91VA6 baseline and differential
GenevisibleiQ91VA6 MM

Interactioni

Subunit structurei

Interacts with PCNA and POLD2.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi212455, 1 interactor
IntActiQ91VA6, 1 interactor
MINTiQ91VA6
STRINGi10090.ENSMUSP00000001127

Structurei

3D structure databases

ProteinModelPortaliQ91VA6
SMRiQ91VA6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini235 – 360ApaGPROSITE-ProRule annotationAdd BLAST126

Phylogenomic databases

eggNOGiKOG4408 Eukaryota
COG2967 LUCA
GeneTreeiENSGT00390000010198
HOGENOMiHOG000008122
HOVERGENiHBG053549
InParanoidiQ91VA6
KOiK17809
OMAiTHTFYQV
OrthoDBiEOG091G0BNI
PhylomeDBiQ91VA6
TreeFamiTF314882

Family and domain databases

Gene3Di2.60.40.1470, 1 hit
InterProiView protein in InterPro
IPR007474 ApaG_domain
IPR036767 ApaG_sf
IPR011722 Hemimethylated_DNA-bd_dom
IPR036623 Hemimethylated_DNA-bd_sf
PfamiView protein in Pfam
PF04379 DUF525, 1 hit
PF08755 YccV-like, 1 hit
SMARTiView protein in SMART
SM00992 YccV-like, 1 hit
SUPFAMiSSF110069 SSF110069, 1 hit
SSF141255 SSF141255, 2 hits
PROSITEiView protein in PROSITE
PS51087 APAG, 1 hit

Sequencei

Sequence statusi: Complete.

Q91VA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGCVARRAL AVGSRWWSRS LATTRGSRPL CAVGGAGGLP PVATATTRRH
60 70 80 90 100
LSSRNRAEGK VLETVGVFEV PKQNGKYETG QLFLHSVFGY RGVVLFPWQA
110 120 130 140 150
RLYDRDVASA TPEKAENPAG HGSKEVKGKT HTYYQVLIDA RDCPHISQRS
160 170 180 190 200
QTEAVTFLAN HDDSRALYAI PGLDYVSHED ILPYTSTDQV PIQHELFERF
210 220 230 240 250
LLYDQTKAPP FVARETLRAW QEKNHPWLEL SDVHRETTEN IRVTVIPFYM
260 270 280 290 300
GMREAQNSHV YWWRYCIRLE NLDSDVVQLR ERHWRIFSLS GTLETVRGRG
310 320 330 340 350
VVGREPVLSK EQPAFQYSSH VSLQASSGHM WGTFRFERPD GSHFDVRIPP
360
FSLESNKDEK TPPSGLHW
Length:368
Mass (Da):41,870
Last modified:December 1, 2001 - v1
Checksum:i4A399A13C795FCBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC006833 mRNA Translation: AAH06833.1
BC012879 mRNA Translation: AAH12879.1
CCDSiCCDS25109.1
RefSeqiNP_080665.1, NM_026389.3
UniGeneiMm.197493

Genome annotation databases

EnsembliENSMUST00000001127; ENSMUSP00000001127; ENSMUSG00000001100
GeneIDi67811
KEGGimmu:67811
UCSCiuc007kjo.1 mouse

Similar proteinsi

Entry informationi

Entry nameiPDIP2_MOUSE
AccessioniPrimary (citable) accession number: Q91VA6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health