Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein S100

Gene

S100a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi63 – 74PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-5686938 Regulation of TLR by endogenous ligand

Names & Taxonomyi

Protein namesi
Recommended name:
Protein S100UniRule annotation
Alternative name(s):
S100 calcium-binding proteinUniRule annotation
Gene namesi
Name:S100a1Imported
ORF Names:mCG_68132Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1338917 S100a1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ91V77

Expressioni

Gene expression databases

BgeeiENSMUSG00000044080

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 85EF-handInterPro annotationAdd BLAST36

Sequence similaritiesi

Belongs to the S-100 family.UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IXZ2 Eukaryota
ENOG4111987 LUCA
GeneTreeiENSGT00760000119034
HOVERGENiHBG001479
OMAiTAAMGSE
OrthoDBiEOG091G10JX
TreeFamiTF332727

Family and domain databases

CDDicd05025 S-100A1, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR028486 S100-A1
IPR001751 S100/CaBP-9k_CS
IPR013787 S100_Ca-bd_sub
PANTHERiPTHR11639:SF66 PTHR11639:SF66, 1 hit
PfamiView protein in Pfam
PF00036 EF-hand_1, 1 hit
PF01023 S_100, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 1 hit
SM01394 S_100, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
PS00303 S100_CABP, 1 hit

Sequencei

Sequence statusi: Complete.

Q91V77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSELESAME TLINVFHAHS GKEGDKYKLS KKELKDLLQT ELSGFLDVQK
60 70 80 90
DADAVDKVMK ELDENGDGEV DFKEYVVLVA ALTVACNNFF WETS
Length:94
Mass (Da):10,505
Last modified:December 1, 2001 - v1
Checksum:i7C8E817BBF36ED15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160552 Genomic DNA No translation available.
BC005590 mRNA Translation: AAH05590.1
AF368423 Genomic DNA Translation: AAL14436.1
AK002721 mRNA Translation: BAB22308.1
AK012578 mRNA Translation: BAB28330.1
AK168822 mRNA Translation: BAE40649.1
CH466547 Genomic DNA Translation: EDL15127.1
RefSeqiNP_035439.1, NM_011309.3
UniGeneiMm.24662

Genome annotation databases

EnsembliENSMUST00000060738; ENSMUSP00000058237; ENSMUSG00000044080
GeneIDi20193
KEGGimmu:20193
UCSCiuc008qct.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ91V77_MOUSE
AccessioniPrimary (citable) accession number: Q91V77
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: June 20, 2018
This is version 152 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health