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Q91V48 (Q91V48_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Protein Pcdhb21 Ensembl ENSMUSP00000056424

Protocadherin beta 21 EMBL AAI38122.1

Protocadherin-betaU EMBL AAK53239.1
Gene names
Name:Pcdhb21 MGI 2136759 EMBL AAI38122.1 Ensembl ENSMUSP00000056424
Synonyms:Pcdhb18 EMBL AAK53239.1
ORF Names:mCG_1033322 EMBL EDL10150.1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length774 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain By similarity. SAAS SAAS015919

Sequence similarities

Contains cadherin domains. SAAS SAAS015919

Sequences

Sequence LengthMass (Da)Tools
Q91V48 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: B1BCD215E09595DE

FASTA77485,231
        10         20         30         40         50         60 
MEPGVGAAQH IRQVLLFFVF LEGSSVLATT WRYSVPEEME TGSSIANIIK DMDVGDLAAR 

        70         80         90        100        110        120 
GARVIFDDYQ PYLRLELETG NLLLNEKLDR EALCSSSEPC ILHFQVLLEN PLQFFQAELL 

       130        140        150        160        170        180 
IEDINDHTPT FLEKLIFLNI SESATPGTSF QMDDAQDLDI GMNGIQNYSI SPNPYFYLKL 

       190        200        210        220        230        240 
KDSGKGRRYP ELVLVRSLDR EKEASISLIL TAMDGGSLPR SGTVLVQVVV LDVNDNAPEF 

       250        260        270        280        290        300 
ERTLYEVQVP ENSSVDSLVI KVSATDLDSG INGEISYSFS HISRDVQKTF EIHPTSGEVR 

       310        320        330        340        350        360 
LKRLLDFEVI QSYTINIQAI DGGGLSGKSA IIVQVTDVND NPPEIVITSL MSSIPENGLS 

       370        380        390        400        410        420 
EMVVAVFSLR DQDSGENGRM MCSIEDKLPF LLKPTFKNFY TLVTEHPLDR ESRAEYNITV 

       430        440        450        460        470        480 
MISDLGTPRL TTQHTITVHI SDINDNAPAF TQTTYTMFVR ENNSPALHIG TISATDSDLG 

       490        500        510        520        530        540 
SNAHITYSLL PPQDQRLALT SLISINADNG QLFALRALDY ETLQAFEFRV GATDRGSPAL 

       550        560        570        580        590        600 
SSQALVRVVV LDDNDNAPFV LYPMQNASAP CTELLPRAAE PGYLVTKVVA VDRDSGQNAW 

       610        620        630        640        650        660 
LSFQLLKATE PGLFSVWAHN GEVRTTRLLS ERDVPKHRLL LLVKDNGDPP RSASVTLHLL 

       670        680        690        700        710        720 
VVDGFSQPYL PLPEVAHDST QVDEEALTLY LVIALASVSS LFLLSVLLFV GVRLCRRARA 

       730        740        750        760        770 
ASLSGYSEPD GHFSGHLVDV SGAGTLSQSY QYEVCLTGMS DSNDIRFLKP VSQP 

« Hide

References

« Hide 'large scale' references
[1]"A striking organization of a large family of human neural cadherin-like cell adhesion genes."
Wu Q., Maniatis T.
Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26072.1.
[2]"Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
Wu Q., Maniatis T.
Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26072.1.
[3]"The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number."
Vanhalst K., Kools P., Vanden Eynde E., van Roy F.
FEBS Lett. 495:120-125(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BALB/C EMBL AAK53239.1.
[4]"Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."
Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M., Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.
Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26072.1.
[5]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL10150.1.
[6]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain EMBL AAI38122.1.
[7]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL10150.1.
[8]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000056424.
[9]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000056424.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC020967 Genomic DNA. No translation available.
BC138121 mRNA. Translation: AAI38122.1.
BC138122 mRNA. Translation: AAI38123.1.
AY013783 mRNA. Translation: AAK26072.1.
AF326314 mRNA. Translation: AAK53239.1.
CH466528 Genomic DNA. Translation: EDL10150.1.
RefSeqNP_444376.1. NM_053146.2.
UniGeneMm.348053.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000061405; ENSMUSP00000056424; ENSMUSG00000044022.
GeneID93892.
KEGGmmu:93892.

Organism-specific databases

CTD93892.
MGIMGI:2136759. Pcdhb21.

Phylogenomic databases

GeneTreeENSGT00600000084235.
HOVERGENHBG054878.
InParanoidQ91V48.
KOK16494.
OMAFEIHPIS.
OrthoDBEOG7KSX80.
TreeFamTF332299.

Gene expression databases

GenevestigatorQ91V48.

Family and domain databases

Gene3D2.60.40.60. 5 hits.
InterProIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view]
PfamPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSPR00205. CADHERIN.
SMARTSM00112. CA. 5 hits.
[Graphical view]
SUPFAMSSF49313. SSF49313. 6 hits.
PROSITEPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio351837.
SOURCESearch...

Entry information

Entry nameQ91V48_MOUSE
AccessionPrimary (citable) accession number: Q91V48
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)