Q91LS8Q91LS8_9INFAHemagglutininHAInfluenza A virusA/Taiwan/0095/1996(H3N2)VirusesRiboviriaOrthornaviraeNegarnaviricotaPolyploviricotinaInsthoviricetesArticulaviralesOrthomyxoviridaeAlphainfluenzavirusAlphainfluenzavirus influenzaeInfluenza A virusBrowser-Based Java Applications for Search and Analysis of Influenza Sequences in GenBank Format.NUCLEOTIDE SEQUENCEZinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 260-272Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.Homotrimer of disulfide-linked HA1-HA2.Apical cell membraneSingle-pass type I membrane proteinCell membraneSingle-pass type I membrane proteinHost apical cell membraneSingle-pass type I membrane proteinMembraneSingle-pass type I membrane proteinBelongs to the influenza viruses hemagglutinin family.3D-structureClathrin- and caveolin-independent endocytosis of virus by hostClathrin-mediated endocytosis of virus by hostDisulfide bondFusion of virus membrane with host endosomal membraneFusion of virus membrane with host membraneGlycoproteinHemagglutininHost cell membraneHost membraneHost-virus interactionLipoproteinMembranePalmitateViral attachment to host cellViral envelope proteinViral penetration into host cytoplasmVirionVirus endocytosis by hostVirus entry into host cellSTGRICDSPHRILDGKNCTLIDALLGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFTNEGFNWTGVAQNGTSYACKRGSVKSFFSRLNWLHKLEYKYPALNVTMPNNDKFDKLYIWGVHHPSTDSDQTSLYVQASGRITVSTKRSQQTVIPNIGSRPWVRGVSSIISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGNCNSECITPNGSIPNDKPFQNVNRITYGACPKYVKQNTLKLATGMRNVPEKQ
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