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Q91FW5

- VF205_IIV6

UniProt

Q91FW5 - VF205_IIV6

Protein

Putative DNA ligase 205R

Gene

IIV6-205R

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.By similarity

    Catalytic activityi

    NAD+ + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + beta-nicotinamide D-ribonucleotide + (deoxyribonucleotide)(n+m).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei101 – 1011N6-AMP-lysine intermediateBy similarity

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. DNA ligase (NAD+) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA repair Source: InterPro
    2. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    DNA replication

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative DNA ligase 205R (EC:6.5.1.2)
    Gene namesi
    ORF Names:IIV6-205R
    OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
    Taxonomic identifieri176652 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
    Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
    Chilo suppressalis (striped riceborer) [TaxID: 168631]
    Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
    Gryllus campestris [TaxID: 58607]
    Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
    ProteomesiUP000001359: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 615615Putative DNA ligase 205RPRO_0000376962Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ91FW5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAD-dependent DNA ligase family.Curated

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.40.50.10190. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR001679. DNAligase.
    IPR013839. DNAligase_adenylation.
    IPR013840. DNAligase_N.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR012340. NA-bd_OB-fold.
    IPR004150. NAD_DNA_ligase_OB.
    IPR010994. RuvA_2-like.
    [Graphical view]
    PfamiPF01653. DNA_ligase_aden. 1 hit.
    PF03120. DNA_ligase_OB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001604. LigA. 1 hit.
    SMARTiSM00278. HhH1. 1 hit.
    SM00532. LIGANc. 1 hit.
    [Graphical view]
    SUPFAMiSSF47781. SSF47781. 1 hit.
    SSF50249. SSF50249. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q91FW5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDETQQLLYK FKNLTISENE KLKLKEKADH FYFNTEKEIL TDNEYDILAE    50
    QLQSTNVGCS PLISKTDLPL WMGSLDKVYN DKELNLWIKK VASDKYIIQC 100
    KLDGVSCLII NKDNKLKAYT RGNGKVGTDI SHLIKYFIKD KCLPNNIALR 150
    CEIIIKKETF NQKYKHAFSN PRSFVSGVVN RKQENIVISE LNDLCLIAYE 200
    LINFPVNEYQ KNILTQIEII EQLNFIQFVN FKTISNEFLT QKALSNLFKE 250
    MKNNSLFEMD GLVILANTPY IRVTEGNPKH SIAFKVRGDN VKEAKVTFIE 300
    WNVGKTGVFT PKVHIVPTEI NGTTVSCFTG FNANYLIEKG IGEGAIILVT 350
    RAGDAIPQII GVKQTGVLTF PKDYEWKGDC RIVEKIESKE RIIKQILHFV 400
    ESVDIPYIKE ATINKLYNNG CTSIELFLKL TQKDLLLFGP KLSSTIYNSI 450
    QKSFEAPIEK FLSGYNAFGD YIGEKKILLL LQKYPNLFEL ENLDAIDLVS 500
    IEGIGSKTAT QIKQHFINAK LIYNNIIQNK LFKGVLHTPS KQNTVELFKV 550
    CVSGTRDPLF IQELKNRGFV LSDNITKKVK VLIVKNSNEE TTKVKKANSV 600
    GITILTLEDF KQKYF 615
    Length:615
    Mass (Da):70,152
    Last modified:December 1, 2001 - v1
    Checksum:iA3B98D1C37B317A8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAK82067.1.
    RefSeqiNP_149668.1. NC_003038.1.

    Genome annotation databases

    GeneIDi1733308.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAK82067.1 .
    RefSeqi NP_149668.1. NC_003038.1.

    3D structure databases

    ProteinModelPortali Q91FW5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1733308.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.40.50.10190. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR001679. DNAligase.
    IPR013839. DNAligase_adenylation.
    IPR013840. DNAligase_N.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR012340. NA-bd_OB-fold.
    IPR004150. NAD_DNA_ligase_OB.
    IPR010994. RuvA_2-like.
    [Graphical view ]
    Pfami PF01653. DNA_ligase_aden. 1 hit.
    PF03120. DNA_ligase_OB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001604. LigA. 1 hit.
    SMARTi SM00278. HhH1. 1 hit.
    SM00532. LIGANc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47781. SSF47781. 1 hit.
    SSF50249. SSF50249. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
      Jakob N.J., Mueller K., Bahr U., Darai G.
      Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
      Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
      Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.

    Entry informationi

    Entry nameiVF205_IIV6
    AccessioniPrimary (citable) accession number: Q91FW5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3