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Q91FU7

- VF224_IIV6

UniProt

Q91FU7 - VF224_IIV6

Protein

Probable cysteine proteinase 224L

Gene

IIV6-224L

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Probable cysteine protease.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei99 – 991PROSITE-ProRule annotation
    Active sitei292 – 2921PROSITE-ProRule annotation
    Active sitei322 – 3221PROSITE-ProRule annotation

    GO - Molecular functioni

    1. cysteine-type peptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol protease

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cysteine proteinase 224L (EC:3.4.-.-)
    Gene namesi
    ORF Names:IIV6-224L
    OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
    Taxonomic identifieri176652 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
    Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
    Chilo suppressalis (striped riceborer) [TaxID: 168631]
    Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
    Gryllus campestris [TaxID: 58607]
    Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
    ProteomesiUP000001359: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 449449Probable cysteine proteinase 224LPRO_0000376964Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ91FU7.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei429 – 44921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase C1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Family and domain databases

    InterProiIPR000169. Pept_cys_AS.
    IPR013128. Peptidase_C1A.
    IPR000668. Peptidase_C1A_C.
    IPR015643. Peptidase_C1A_cathepsin-B.
    [Graphical view]
    PANTHERiPTHR12411. PTHR12411. 1 hit.
    PTHR12411:SF16. PTHR12411:SF16. 1 hit.
    PfamiPF00112. Peptidase_C1. 1 hit.
    [Graphical view]
    PROSITEiPS00139. THIOL_PROTEASE_CYS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q91FU7-1 [UniParc]FASTAAdd to Basket

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    MKTKNRLLNS DIDFVNESIP YSRSDFNNML TKLSSNDYYQ LMVNTYIGTY    50
    GSAKFFGEST KTLPENFNWK TITEFDPPSI VSKKKLISEP ENQYLCGNCW 100
    AMSTVQTIGD RFVVAGLVNW VPDLSTTFAM LYYPQGQCDG GNSAKLMRQI 150
    HTGIGLASKH CIDYSWCSRN IECKTDNSLG HFVSENKSYL LPSKKGCYYN 200
    SKHYIYKIDS RPKIISGYGT LNTDNEVLNN QILLKQEILA NGPAVGGFLV 250
    FENFTSAFTK VNGGVYLENV SNYGSGKPVE FNPHINKYSG NHVVSILGWG 300
    VAKGIKISNT QFSDVPYWFC RNTWGKNWGD KGYFKIAMYP FNKKSQFLKL 350
    VSIVDHEGHT RRNSGVVICN VSETPILQSL PVIPSTEIPK SLDNSTNFYS 400
    QDENYEIKNN SQNEKGFPKG NRRRTTSSDT QIVFIFFLSV VILFIFIIL 449
    Length:449
    Mass (Da):50,789
    Last modified:December 1, 2001 - v1
    Checksum:i3AB70304E178D232
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAK82086.1.
    RefSeqiNP_149687.1. NC_003038.1.

    Genome annotation databases

    GeneIDi1733244.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAK82086.1 .
    RefSeqi NP_149687.1. NC_003038.1.

    3D structure databases

    ProteinModelPortali Q91FU7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1733244.

    Family and domain databases

    InterProi IPR000169. Pept_cys_AS.
    IPR013128. Peptidase_C1A.
    IPR000668. Peptidase_C1A_C.
    IPR015643. Peptidase_C1A_cathepsin-B.
    [Graphical view ]
    PANTHERi PTHR12411. PTHR12411. 1 hit.
    PTHR12411:SF16. PTHR12411:SF16. 1 hit.
    Pfami PF00112. Peptidase_C1. 1 hit.
    [Graphical view ]
    PROSITEi PS00139. THIOL_PROTEASE_CYS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
      Jakob N.J., Mueller K., Bahr U., Darai G.
      Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
      Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
      Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.

    Entry informationi

    Entry nameiVF224_IIV6
    AccessioniPrimary (citable) accession number: Q91FU7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3