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Q91FU7

- VF224_IIV6

UniProt

Q91FU7 - VF224_IIV6

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Protein

Probable cysteine proteinase 224L

Gene

IIV6-224L

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Probable cysteine protease.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei99 – 991PROSITE-ProRule annotation
Active sitei292 – 2921PROSITE-ProRule annotation
Active sitei322 – 3221PROSITE-ProRule annotation

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine proteinase 224L (EC:3.4.-.-)
Gene namesi
ORF Names:IIV6-224L
OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Taxonomic identifieri176652 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
ProteomesiUP000001359: Genome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Probable cysteine proteinase 224LPRO_0000376964Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ91FU7.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei429 – 44921HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

InterProiIPR000169. Pept_cys_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR015643. Peptidase_C1A_cathepsin-B.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PTHR12411:SF16. PTHR12411:SF16. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
PROSITEiPS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91FU7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKTKNRLLNS DIDFVNESIP YSRSDFNNML TKLSSNDYYQ LMVNTYIGTY
60 70 80 90 100
GSAKFFGEST KTLPENFNWK TITEFDPPSI VSKKKLISEP ENQYLCGNCW
110 120 130 140 150
AMSTVQTIGD RFVVAGLVNW VPDLSTTFAM LYYPQGQCDG GNSAKLMRQI
160 170 180 190 200
HTGIGLASKH CIDYSWCSRN IECKTDNSLG HFVSENKSYL LPSKKGCYYN
210 220 230 240 250
SKHYIYKIDS RPKIISGYGT LNTDNEVLNN QILLKQEILA NGPAVGGFLV
260 270 280 290 300
FENFTSAFTK VNGGVYLENV SNYGSGKPVE FNPHINKYSG NHVVSILGWG
310 320 330 340 350
VAKGIKISNT QFSDVPYWFC RNTWGKNWGD KGYFKIAMYP FNKKSQFLKL
360 370 380 390 400
VSIVDHEGHT RRNSGVVICN VSETPILQSL PVIPSTEIPK SLDNSTNFYS
410 420 430 440
QDENYEIKNN SQNEKGFPKG NRRRTTSSDT QIVFIFFLSV VILFIFIIL
Length:449
Mass (Da):50,789
Last modified:December 1, 2001 - v1
Checksum:i3AB70304E178D232
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF303741 Genomic DNA. Translation: AAK82086.1.
RefSeqiNP_149687.1. NC_003038.1.

Genome annotation databases

GeneIDi1733244.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF303741 Genomic DNA. Translation: AAK82086.1 .
RefSeqi NP_149687.1. NC_003038.1.

3D structure databases

ProteinModelPortali Q91FU7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1733244.

Family and domain databases

InterProi IPR000169. Pept_cys_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR015643. Peptidase_C1A_cathepsin-B.
[Graphical view ]
PANTHERi PTHR12411. PTHR12411. 1 hit.
PTHR12411:SF16. PTHR12411:SF16. 1 hit.
Pfami PF00112. Peptidase_C1. 1 hit.
[Graphical view ]
PROSITEi PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
    Jakob N.J., Mueller K., Bahr U., Darai G.
    Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
    Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
    Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.

Entry informationi

Entry nameiVF224_IIV6
AccessioniPrimary (citable) accession number: Q91FU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: December 1, 2001
Last modified: October 1, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3