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Protein

Putative ubiquitin thioesterase 232R

Gene

IIV6-232R

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.By similarity

Catalytic activityi

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei400By similarity1
Active sitei403NucleophileBy similarity1
Active sitei514By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ubiquitin thioesterase 232R (EC:3.4.19.12By similarity)
Gene namesi
ORF Names:IIV6-232R
OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Taxonomic identifieri176652 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (Asiatic rice borer moth) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
Proteomesi
  • UP000001359 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003777741 – 671Putative ubiquitin thioesterase 232RAdd BLAST671

Structurei

3D structure databases

ProteinModelPortaliQ91FU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini392 – 521OTUPROSITE-ProRule annotationAdd BLAST130

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi255 – 352Arg/Ser-richAdd BLAST98
Compositional biasi548 – 581Glu-richAdd BLAST34

Sequence similaritiesi

Contains 1 OTU domain.PROSITE-ProRule annotation

Family and domain databases

InterProiIPR014901. 2-cysteine_adaptor.
IPR003323. OTU_dom.
IPR011112. Rho_N.
[Graphical view]
PfamiPF08793. 2C_adapt. 1 hit.
PF02338. OTU. 1 hit.
[Graphical view]
SMARTiSM00959. Rho_N. 3 hits.
[Graphical view]
PROSITEiPS50802. OTU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91FU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNNQCMRKK LDELRNIARS YNISITGKKK QQLCDEIIDY QKNNPPRRSP
60 70 80 90 100
SPRRSPSPRR ISPECEQWLA NKGINPRTGK AIKIGGPTYK KLEMECKEAS
110 120 130 140 150
PKIPSPVRQP SPVHSPVRSP VRQPSPVRFV EKTKGALNKM KKDQLIDFAQ
160 170 180 190 200
SLGLNPGKLL KPALVDLIFV NQKPPRRSPS PRRSPSPRRS PSPRRSPSPR
210 220 230 240 250
PVFVEKTKGA LNKMKKDQLI DLAQSLGLNP GKLLKPALVD LIFVNQKPVE
260 270 280 290 300
PIRASSSSRS SRSTRRSSST KPSRRSSSRS RRSSSRSRRS SSRSRRSSSR
310 320 330 340 350
SRRSSRRSTS RSRSLSKRSI RNISTVGDLE DLVASNLPIA IPESLSRSLS
360 370 380 390 400
PSRTDFHEAE IELGSDFDLN NLPENRIAEL KQLNVLAKQN GFRMINVPLD
410 420 430 440 450
GNCMFSVIGR AFNTSSSVIR QHTVDYLRRC KGSFDHIPAN IDDPTINWND
460 470 480 490 500
YIDRLEEDAC WGDNTALFAA SLALNFQAHI LQVAGGDEGS WIRFGVNETN
510 520 530 540 550
MGRIVNMGYL DNFHYIALEP FSGRLDILSI PSTHSKCPPP EISNRRDEEI
560 570 580 590 600
RRDEEVEDEV IGERIVREAE VIERELRQEE ELTSIVSTKR SLRPSIPPKI
610 620 630 640 650
STEHRRTPKL RPSVPRPSSI RQSQPNVAAL ARLETLTKIK DIIDALQRPL
660 670
ENKLSTLTNT EKAIMQCIGV A
Length:671
Mass (Da):75,605
Last modified:December 1, 2001 - v1
Checksum:i1FD36D7AC7D67CCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAK82093.1.
RefSeqiNP_149695.1. NC_003038.1.

Genome annotation databases

GeneIDi1733388.
KEGGivg:1733388.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAK82093.1.
RefSeqiNP_149695.1. NC_003038.1.

3D structure databases

ProteinModelPortaliQ91FU0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1733388.
KEGGivg:1733388.

Family and domain databases

InterProiIPR014901. 2-cysteine_adaptor.
IPR003323. OTU_dom.
IPR011112. Rho_N.
[Graphical view]
PfamiPF08793. 2C_adapt. 1 hit.
PF02338. OTU. 1 hit.
[Graphical view]
SMARTiSM00959. Rho_N. 3 hits.
[Graphical view]
PROSITEiPS50802. OTU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVF232_IIV6
AccessioniPrimary (citable) accession number: Q91FU0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: December 1, 2001
Last modified: April 13, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.