Q91FG3 (361L_IIV6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable cysteine proteinase 361L
EC=3.4.-.-

Gene names

ORF Names:

IIV6-361L

Organism

Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) [Reference proteome]

Taxonomic identifier

176652 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Iridovirus

Virus host

Acheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]

Protein attributes

Sequence length	542 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probable cysteine protease.
Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the peptidase C1 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Hydrolase Protease Thiol protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	cysteine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 542	542	Probable cysteine proteinase 361L		PRO_0000377499
Regions
	Transmembrane	520 – 540	21	Helical; Potential
Sites
	Active site	172	1	By similarity
	Active site	382	1	By similarity
	Active site	414	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q91FG3 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 7588C036640CCB5E	FASTA	542	60,620
	10 20 30 40 50 60 MTSIINQRWP LGNLMDGFPN GEKQNKLSFG GVPEKGYFEE FNKDPKYISF SGTPEKAYFE 70 80 90 100 110 120 EFNRYRNIDE DDNRDTFPLF NEISSNPESE SYLQTFVDNV RINTDINFVS KTNSFSQNDL 130 140 150 160 170 180 SYLNATYVDK SLSLELPIKF NWAKTTSADS PDVVAKKKLI SKPDNQYLCG SCWAVSVAGV 190 200 210 220 230 240 VGDVFAVAGL VNWVPNISAT YALIHYPQGR CKGGDPATLL YNIANNGIPS KHCVDYSWCS 250 260 270 280 290 300 QNRTCTTADS AAHFGSDLSP LIPKDRGCYF DSEHYIFKID SNIRTIVAGS GAIDVSNVQR 310 320 330 340 350 360 TIKEYIYTTG PAVGGYIIFR NFTSKVPFGP HKGNSTFNVI NGGVYLEKAN YAQYRGEYGE 370 380 390 400 410 420 HITEGLTFSS SNTDSDNYAG GHAISIMGWG IQPRIRVGNG PNDIADVPYW YCRNSWGTKW 430 440 450 460 470 480 GMNGGYFKIA MYPYNRKSQF SKIVELMTPQ GQHIRLGGVL AFTVSNPPVL KKLPANKQPP 490 500 510 520 530 540 NPNSLSKLLD YYKNDEDDIV TKLPNIVPPS DGKKSTTSKT NNWYIYALII IFILIIFFVL RK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus." Jakob N.J., Mueller K., Bahr U., Darai G. Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes." Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R. Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF303741 Genomic DNA. Translation: AAK82221.1.
RefSeq	NP_149824.1. NC_003038.1.
3D structure databases
ProteinModelPortal	Q91FG3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1733399.
Phylogenomic databases
ProtClustDB	CLSP2511498.
Family and domain databases
InterPro	IPR000169. Pept_cys_AS. IPR013128. Peptidase_C1A. IPR000668. Peptidase_C1A_C. [Graphical view]
PANTHER	PTHR12411. PTHR12411. 1 hit.
Pfam	PF00112. Peptidase_C1. 2 hits. [Graphical view]
PRINTS	PR00705. PAPAIN.
PROSITE	PS00640. THIOL_PROTEASE_ASN. False negative. PS00139. THIOL_PROTEASE_CYS. 1 hit. PS00639. THIOL_PROTEASE_HIS. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

361L_IIV6

Accession

Primary (citable) accession number: Q91FG3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2009
Last sequence update:	December 1, 2001
Last modified:	May 29, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program