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Q91FF5 (VF369_IIV6) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probable endonuclease Potential.

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subcellular location

Host nucleus By similarity.

Sequence similarities

Belongs to the XPG/RAD2 endonuclease family.

Ontologies

Keywords
   Cellular componentHost nucleus
   LigandMagnesium
Metal-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA repair

Inferred from electronic annotation. Source: InterPro

   Cellular_componenthost cell nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

endonuclease activity

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 415415Probable RAD2-like endonuclease 369L
PRO_0000377501

Regions

Region1 – 114114N-domain By similarity
Region163 – 297135I-domain By similarity

Sites

Metal binding341Magnesium 1 By similarity
Metal binding861Magnesium 1 By similarity
Metal binding1981Magnesium 1 By similarity
Metal binding2001Magnesium 1 By similarity
Metal binding2191Magnesium 2 By similarity
Metal binding2211Magnesium 2 By similarity
Metal binding2771Magnesium 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q91FF5 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: CE6E457A686F11F3

FASTA41549,317
        10         20         30         40         50         60 
MGIKNLTKFI KEKCQEAYVT ENINELSFKK IAIDTPMYMY KYKSMNAAKM VENNGIYYNP 

        70         80         90        100        110        120 
DGWLWSFIYF IYSLRKHDIH PIFILEGGYP EEKNKTRMAR KKDREDVKKK TLSLEESISS 

       130        140        150        160        170        180 
YATSLRLRPE DIPQDLKEEW NKIAKKNNLP FEDFDFETVK DHVKQRHRYD IRITNRDYEK 

       190        200        210        220        230        240 
LKILLKIMNT PFIQAPMEAE AFCAYLYKKK IIHGIASNDS DILAYGCNLI VDFEFDVKID 

       250        260        270        280        290        300 
EETKISKITY INYDYLLNKL DLQSSEFLDF CIMCGTDYND NIYRIGAVKS YELIKVQKCI 

       310        320        330        340        350        360 
ENVGKFLDPN NKKGTILILN HLRIRHIFNH YGMKNIDDVT NMQFLEKKAS WSSVPNFYLL 

       370        380        390        400        410 
TMLTIKFNIN IDLEWIRHGF EKCNIKWDCE SEYEENVEKT NVEETNNEVD EFPIF 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
Jakob N.J., Mueller K., Bahr U., Darai G.
Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF303741 Genomic DNA. Translation: AAK82229.1.
RefSeqNP_149832.1. NC_003038.1.

3D structure databases

ProteinModelPortalQ91FF5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1733029.

Phylogenomic databases

ProtClustDBCLSP2511689.

Family and domain databases

InterProIPR020045. 5-3_exonuclease_C.
IPR006086. XPG-I_dom.
IPR006084. XPG/Rad2.
IPR006085. XPG_DNA_repair_N.
[Graphical view]
PANTHERPTHR11081. PTHR11081. 1 hit.
PfamPF00867. XPG_I. 1 hit.
PF00752. XPG_N. 1 hit.
[Graphical view]
PRINTSPR00853. XPGRADSUPER.
SMARTSM00484. XPGI. 1 hit.
SM00485. XPGN. 1 hit.
[Graphical view]
SUPFAMSSF47807. SSF47807. 1 hit.
ProtoNetSearch...

Entry information

Entry nameVF369_IIV6
AccessionPrimary (citable) accession number: Q91FF5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: December 1, 2001
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families