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Q91FF5

- VF369_IIV6

UniProt

Q91FF5 - VF369_IIV6

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Protein

Probable RAD2-like endonuclease 369L

Gene

IIV6-369L

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Probable endonuclease.Curated

Cofactori

Mg2+By similarityNote: Binds 2 magnesium ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi34 – 341Magnesium 1By similarity
Metal bindingi86 – 861Magnesium 1By similarity
Metal bindingi198 – 1981Magnesium 1By similarity
Metal bindingi200 – 2001Magnesium 1By similarity
Metal bindingi219 – 2191Magnesium 2By similarity
Metal bindingi221 – 2211Magnesium 2By similarity
Metal bindingi277 – 2771Magnesium 2By similarity

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. endonuclease activity Source: UniProtKB-KW
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable RAD2-like endonuclease 369L (EC:3.1.-.-)
Gene namesi
ORF Names:IIV6-369L
OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Taxonomic identifieri176652 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
ProteomesiUP000001359: Genome

Subcellular locationi

Host nucleus By similarity

GO - Cellular componenti

  1. host cell nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 415415Probable RAD2-like endonuclease 369LPRO_0000377501Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ91FF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 114114N-domainBy similarityAdd
BLAST
Regioni163 – 297135I-domainBy similarityAdd
BLAST

Sequence similaritiesi

Belongs to the XPG/RAD2 endonuclease family.Curated

Family and domain databases

Gene3Di3.40.50.1010. 2 hits.
InterProiIPR020045. 5-3_exonuclease_C.
IPR029060. PIN_domain-like.
IPR006086. XPG-I_dom.
IPR006085. XPG_DNA_repair_N.
[Graphical view]
PfamiPF00867. XPG_I. 1 hit.
PF00752. XPG_N. 1 hit.
[Graphical view]
SMARTiSM00484. XPGI. 1 hit.
SM00485. XPGN. 1 hit.
[Graphical view]
SUPFAMiSSF47807. SSF47807. 1 hit.
SSF88723. SSF88723. 2 hits.

Sequencei

Sequence statusi: Complete.

Q91FF5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGIKNLTKFI KEKCQEAYVT ENINELSFKK IAIDTPMYMY KYKSMNAAKM
60 70 80 90 100
VENNGIYYNP DGWLWSFIYF IYSLRKHDIH PIFILEGGYP EEKNKTRMAR
110 120 130 140 150
KKDREDVKKK TLSLEESISS YATSLRLRPE DIPQDLKEEW NKIAKKNNLP
160 170 180 190 200
FEDFDFETVK DHVKQRHRYD IRITNRDYEK LKILLKIMNT PFIQAPMEAE
210 220 230 240 250
AFCAYLYKKK IIHGIASNDS DILAYGCNLI VDFEFDVKID EETKISKITY
260 270 280 290 300
INYDYLLNKL DLQSSEFLDF CIMCGTDYND NIYRIGAVKS YELIKVQKCI
310 320 330 340 350
ENVGKFLDPN NKKGTILILN HLRIRHIFNH YGMKNIDDVT NMQFLEKKAS
360 370 380 390 400
WSSVPNFYLL TMLTIKFNIN IDLEWIRHGF EKCNIKWDCE SEYEENVEKT
410
NVEETNNEVD EFPIF
Length:415
Mass (Da):49,317
Last modified:December 1, 2001 - v1
Checksum:iCE6E457A686F11F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAK82229.1.
RefSeqiNP_149832.1. NC_003038.1.

Genome annotation databases

GeneIDi1733029.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAK82229.1 .
RefSeqi NP_149832.1. NC_003038.1.

3D structure databases

ProteinModelPortali Q91FF5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1733029.

Family and domain databases

Gene3Di 3.40.50.1010. 2 hits.
InterProi IPR020045. 5-3_exonuclease_C.
IPR029060. PIN_domain-like.
IPR006086. XPG-I_dom.
IPR006085. XPG_DNA_repair_N.
[Graphical view ]
Pfami PF00867. XPG_I. 1 hit.
PF00752. XPG_N. 1 hit.
[Graphical view ]
SMARTi SM00484. XPGI. 1 hit.
SM00485. XPGN. 1 hit.
[Graphical view ]
SUPFAMi SSF47807. SSF47807. 1 hit.
SSF88723. SSF88723. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
    Jakob N.J., Mueller K., Bahr U., Darai G.
    Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
    Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
    Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.

Entry informationi

Entry nameiVF369_IIV6
AccessioniPrimary (citable) accession number: Q91FF5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: December 1, 2001
Last modified: November 26, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3