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Protein

Probable serine/threonine-protein kinase 380R

Gene

IIV6-380R

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei187 – 1871ATPPROSITE-ProRule annotation
Active sitei302 – 3021Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi162 – 1709ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase 380R (EC:2.7.11.1)
Gene namesi
ORF Names:IIV6-380R
OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Taxonomic identifieri176652 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
ProteomesiUP000001359 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 528528Probable serine/threonine-protein kinase 380RPRO_0000376912Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ91FE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini156 – 507352Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Family and domain databases

InterProiIPR014901. 2-cysteine_adaptor.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
[Graphical view]
PfamiPF08793. 2C_adapt. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91FE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFDKEKCDE WEKIRLNSSP KNPFTKRNVK KDGPTYKKID LICKHNVVGG
60 70 80 90 100
NVVDLNKLCL KWLKDNHPNV KIPKSKSPPK VKSPKRKKSP VRRRVSSPLL
110 120 130 140 150
TDDEDDVLNL QYDYLLSYRS VASEEITNYL RQTINDKTIT AGNACMSNTK
160 170 180 190 200
TLLKYFTNVK AVGKGSFGTV YIGNINIKNN VFSIAIKEGQ ISGLEANRAK
210 220 230 240 250
KLQFPVEYLF NQMMNNILNN KMCPSFNYTY CIHFCDHCEV VSAIFKNPKT
260 270 280 290 300
KSKITTCSVT MVEKADSDLI GLTSLDAQLS ALFQILAAVH CIHKLYGIQH
310 320 330 340 350
CDIKIENVLK KNIPKQANEY FRYSLDGVNY FVPNTGFVAI LNDFGVSFST
360 370 380 390 400
SPKISTSYFG VRNAKVVFNN NSYKFQSFTT QRYPQENKWG KIETLSPPPR
410 420 430 440 450
LRGPGGAKLT LNKFMKNFDS KPSIFVDLED FQKFPTFGMY QDIQDVVRMF
460 470 480 490 500
VGGKQTVQPG SHTEMRGLQP QAKKAILPFV EKLAPTSIWP EDKVELFLAN
510 520
VLIHKIFTQF GYTNAPPNAI ILETYKLP
Length:528
Mass (Da):59,952
Last modified:November 30, 2001 - v1
Checksum:iC3D7381E12E96BA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAK82240.1.
RefSeqiNP_149843.1. NC_003038.1.

Genome annotation databases

GeneIDi1733084.
KEGGivg:1733084.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAK82240.1.
RefSeqiNP_149843.1. NC_003038.1.

3D structure databases

ProteinModelPortaliQ91FE4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1733084.
KEGGivg:1733084.

Family and domain databases

InterProiIPR014901. 2-cysteine_adaptor.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
[Graphical view]
PfamiPF08793. 2C_adapt. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
    Jakob N.J., Mueller K., Bahr U., Darai G.
    Virology 286:182-196(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
    Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
    Virol. J. 4:11-11(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.

Entry informationi

Entry nameiVF380_IIV6
AccessioniPrimary (citable) accession number: Q91FE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2009
Last sequence update: November 30, 2001
Last modified: March 31, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.