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Protein
Submitted name:

Antifreeze protein

Gene

AFP type II

Organism
Clupea harengus (Atlantic herring)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi109Calcium 1Combined sources1
Metal bindingi111Calcium 1Combined sources1
Metal bindingi111Calcium 2Combined sources1
Metal bindingi116Calcium 1Combined sources1
Metal bindingi116Calcium 2Combined sources1
Metal bindingi130Calcium 2Combined sources1
Metal bindingi131Calcium 1Combined sources1
Metal bindingi131Calcium 2Combined sources1

GO - Molecular functioni

Keywordsi

LigandCalciumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Antifreeze proteinImported
Submitted name:
Antifreeze protein type IIImported
Gene namesi
Name:AFP type IIImported
Synonyms:antifreeze protein type IIImported
OrganismiClupea harengus (Atlantic herring)Imported
Taxonomic identifieri7950 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiClupeiClupeiformesClupeoideiClupeidaeClupea

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_501068488318 – 147Sequence analysisAdd BLAST130

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi21 ↔ 32Combined sources
Disulfide bondi49 ↔ 142Combined sources
Disulfide bondi86 ↔ 117Combined sources
Disulfide bondi106 ↔ 128Combined sources
Disulfide bondi118 ↔ 134Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PY2X-ray1.70A/B/C/D/E/F18-147[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 143C-type lectinInterPro annotationAdd BLAST116

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG004151.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR002353. AntifreezeII.
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
PRINTSiPR00356. ANTIFREEZEII.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91992-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTVSLLVCA IVALTRAADE CPTDWKMFNG RCFLFNPLQL HWADAQESCM
60 70 80 90 100
KEGANLASIH SLEESTFVKE LTSADLIPSW IGGTDCQVST RWFWMDSTSM
110 120 130 140
DYADWCAAQP DTTLTECCIQ MNVGIGKCWN DTPCTHLHSS ICAKPLK
Length:147
Mass (Da):16,374
Last modified:November 1, 1996 - v1
Checksum:i0A20C4D0B0885A24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L14722 mRNA. Translation: AAA49200.1.
S65819 mRNA. Translation: AAB28093.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ91992_CLUHA
AccessioniPrimary (citable) accession number: Q91992
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 5, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources