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Protein
Submitted name:

Insulin-like growth factor-I

Gene

IGF-I

Organism
Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor-IImported
Gene namesi
Name:IGF-IImported
OrganismiOncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)Imported
Taxonomic identifieri74940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeOncorhynchus

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 4040Sequence analysisAdd
BLAST
Chaini41 – 188148Sequence analysisPRO_5005942182Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

SMRiQ91965. Positions 45-114.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini47 – 10559IlGFInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG006137.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022341. IGF-I.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02005. INSLNLIKEGF1.
PR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91965-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSGHFFQWH LCDVFKSAMC CVSCTHTLSL LLCVLTLTSA ATGAGPETLC
60 70 80 90 100
GAELVDTLQF VCGERGFYFS KPTGYGPSSR RSHNRGIVDE CCFQSCELRR
110 120 130 140 150
LEMYCAPVKS GKAARSVRAQ RHTDMPRTPK VSTAVQNVDR GTERRTAQHP
160 170 180
DKTKTKKKPL SGNSHTSCKE VHQKNSSRGN TGGRNYRM
Length:188
Mass (Da):20,782
Last modified:November 1, 1996 - v1
Checksum:iF4D705BA811024B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14536 mRNA. Translation: AAA67263.1.
U15960 mRNA. Translation: AAA67266.1.
PIRiA54270.
B54270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14536 mRNA. Translation: AAA67263.1.
U15960 mRNA. Translation: AAA67266.1.
PIRiA54270.
B54270.

3D structure databases

SMRiQ91965. Positions 45-114.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG006137.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022341. IGF-I.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02005. INSLNLIKEGF1.
PR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Duplicate insulin-like growth factor-I genes in salmon display alternative splicing pathways."
    Wallis A.E., Devlin R.H.
    Mol. Endocrinol. 7:409-422(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Big Qualicum RiverImported.
    Tissue: LiverImported.
  2. Devlin R.H.
    Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Big Qualicum RiverImported.
    Tissue: LiverImported.
  3. Devlin R.H.
    Submitted (OCT-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Big Qualicum RiverImported.
    Tissue: LiverImported.

Entry informationi

Entry nameiQ91965_ONCTS
AccessioniPrimary (citable) accession number: Q91965
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.