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Protein
Submitted name:

APP747

Gene

APP747

Organism
Xenopus
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

MEROPSiI02.015

Names & Taxonomyi

Protein namesi
Submitted name:
APP747Imported
Gene namesi
Name:APP747Imported
OrganismiXenopusImported
Taxonomic identifieri8353 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinae

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei678 – 700HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ91963
SMRiQ91963
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini287 – 337BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili233 – 253Sequence analysisAdd BLAST21
Coiled coili380 – 400Sequence analysisAdd BLAST21
Coiled coili402 – 436Sequence analysisAdd BLAST35
Coiled coili532 – 552Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG000051

Family and domain databases

CDDicd00109 KU, 1 hit
Gene3Di1.20.120.770, 1 hit
2.30.29.30, 1 hit
3.30.1490.140, 1 hit
3.90.570.10, 1 hit
4.10.230.10, 1 hit
4.10.410.10, 1 hit
InterProiView protein in InterPro
IPR036669 Amyloid_Cu-bd_sf
IPR008155 Amyloid_glyco
IPR013803 Amyloid_glyco_Abeta
IPR037071 Amyloid_glyco_Abeta_sf
IPR011178 Amyloid_glyco_Cu-bd
IPR024329 Amyloid_glyco_E2_domain
IPR008154 Amyloid_glyco_extra
IPR019744 Amyloid_glyco_extracell_CS
IPR015849 Amyloid_glyco_heparin-bd
IPR036454 Amyloid_glyco_heparin-bd_sf
IPR019745 Amyloid_glyco_intracell_CS
IPR028866 APP
IPR019543 APP_amyloid_C
IPR036176 E2_sf
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR011993 PH-like_dom_sf
IPR020901 Prtase_inh_Kunz-CS
PANTHERiPTHR23103 PTHR23103, 1 hit
PTHR23103:SF7 PTHR23103:SF7, 1 hit
PfamiView protein in Pfam
PF10515 APP_amyloid, 1 hit
PF12924 APP_Cu_bd, 1 hit
PF12925 APP_E2, 1 hit
PF02177 APP_N, 1 hit
PF03494 Beta-APP, 1 hit
PF00014 Kunitz_BPTI, 1 hit
PRINTSiPR00203 AMYLOIDA4
PR00759 BASICPTASE
PR00204 BETAAMYLOID
SMARTiView protein in SMART
SM00006 A4_EXTRA, 1 hit
SM00131 KU, 1 hit
SUPFAMiSSF109843 SSF109843, 1 hit
SSF56491 SSF56491, 1 hit
SSF57362 SSF57362, 1 hit
SSF89811 SSF89811, 1 hit
PROSITEiView protein in PROSITE
PS00319 A4_EXTRA, 1 hit
PS00320 A4_INTRA, 1 hit
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q91963-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPYKLARAD CRRLALEVLV DGNGGLLAEP QIAMFSVARL NMHMNVQNGK
60 70 80 90 100
WETDVSGCIG TKEGILQYCQ EVYPELQITN VVEANQPVTI QNWCKKGRKQ
110 120 130 140 150
CKSRTHIVVP YRCLVGEFVS DALLVPDKCK FLHQERMDIC ETHLHWHTVA
160 170 180 190 200
KESCSEKSMS LHEYGMLLPC GIDKFRGVEF VCCPSAEESE SFDSADAAED
210 220 230 240 250
DCDVWWGGAD ADYVDRSDDK AVEAQPDEEE EVVEVEEEET DDDEDDGDEA
260 270 280 290 300
EEEPEEPYEE ATERTTSIAT TTTTTTESVE EVVREVCSEQ AETGPCRAMI
310 320 330 340 350
SRWYYDVTES KCAQFIYGGC GGNRNNFESD DYCMAVCGSV IPATAASTPD
360 370 380 390 400
AVDKYLENPN DENEHDRFLK AKERLEGKHR EKMSEVMKEW EEAERQAKNL
410 420 430 440 450
PKADKKAVIQ HFQEKVESLE QEAAKQRQQL VETHMARVEA MLNDRRRIAL
460 470 480 490 500
ENYITALQAD PPRPRHVFNM LKKYVRAEQK DRQHTLKHFE HVRMVDPKKA
510 520 530 540 550
AQIRSQVMTH LRVINERMNQ SFSLLYKVPA VAEEIQDEVD ELFQKEQNYS
560 570 580 590 600
DDMVSNMVSD HRVSYGNDAL MPSLSETKTT VELLPVDGEF NIEDLQPWHS
610 620 630 640 650
FGVDSVPANT ENEVEPVDAR PAADRGLTTR PGSGLTNIKT EEISEVKMDS
660 670 680 690 700
EYRHDTAYEV HHQKLVFFAE EVGSNKGAII GLMVGGVVIA TVIVITLVML
710 720 730 740
KKKQYTTIHH GVVEVDAAVT PEERHLTKMQ QNGYENPTYK FFEQMQN
Length:747
Mass (Da):84,893
Last modified:November 1, 1996 - v1
Checksum:iA75E81885681D948
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S52417 mRNA Translation: AAB24853.1

Similar proteinsi

Entry informationi

Entry nameiQ91963_9PIPI
AccessioniPrimary (citable) accession number: Q91963
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health