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Protein
Submitted name:

APP747

Gene

APP747

Organism
Xenopus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

MEROPSiI02.015.

Names & Taxonomyi

Protein namesi
Submitted name:
APP747Imported
Gene namesi
Name:APP747Imported
OrganismiXenopusImported
Taxonomic identifieri8353 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinae

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei678 – 700HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ91963.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini287 – 337BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili402 – 436Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG000051.

Family and domain databases

CDDicd00109. KU. 1 hit.
Gene3Di3.30.1490.140. 1 hit.
3.90.570.10. 1 hit.
4.10.230.10. 1 hit.
4.10.410.10. 1 hit.
InterProiView protein in InterPro
IPR036669. Amyloid_Cu-bd_sf.
IPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR037071. Amyloid_glyco_Abeta_sf.
IPR011178. Amyloid_glyco_Cu-bd.
IPR024329. Amyloid_glyco_E2_domain.
IPR008154. Amyloid_glyco_extra.
IPR019744. Amyloid_glyco_extracell_CS.
IPR015849. Amyloid_glyco_heparin-bd.
IPR036454. Amyloid_glyco_heparin-bd_sf.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
IPR036176. E2_sf.
IPR002223. Kunitz_BPTI.
IPR036880. Kunitz_BPTI_sf.
IPR020901. Prtase_inh_Kunz-CS.
PANTHERiPTHR23103. PTHR23103. 1 hit.
PTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamiView protein in Pfam
PF10515. APP_amyloid. 1 hit.
PF12924. APP_Cu_bd. 1 hit.
PF12925. APP_E2. 1 hit.
PF02177. APP_N. 1 hit.
PF03494. Beta-APP. 1 hit.
PF00014. Kunitz_BPTI. 1 hit.
PRINTSiPR00203. AMYLOIDA4.
PR00759. BASICPTASE.
PR00204. BETAAMYLOID.
SMARTiView protein in SMART
SM00006. A4_EXTRA. 1 hit.
SM00131. KU. 1 hit.
SUPFAMiSSF109843. SSF109843. 1 hit.
SSF56491. SSF56491. 1 hit.
SSF57362. SSF57362. 1 hit.
SSF89811. SSF89811. 1 hit.
PROSITEiView protein in PROSITE
PS00319. A4_EXTRA. 1 hit.
PS00320. A4_INTRA. 1 hit.
PS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91963-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPYKLARAD CRRLALEVLV DGNGGLLAEP QIAMFSVARL NMHMNVQNGK
60 70 80 90 100
WETDVSGCIG TKEGILQYCQ EVYPELQITN VVEANQPVTI QNWCKKGRKQ
110 120 130 140 150
CKSRTHIVVP YRCLVGEFVS DALLVPDKCK FLHQERMDIC ETHLHWHTVA
160 170 180 190 200
KESCSEKSMS LHEYGMLLPC GIDKFRGVEF VCCPSAEESE SFDSADAAED
210 220 230 240 250
DCDVWWGGAD ADYVDRSDDK AVEAQPDEEE EVVEVEEEET DDDEDDGDEA
260 270 280 290 300
EEEPEEPYEE ATERTTSIAT TTTTTTESVE EVVREVCSEQ AETGPCRAMI
310 320 330 340 350
SRWYYDVTES KCAQFIYGGC GGNRNNFESD DYCMAVCGSV IPATAASTPD
360 370 380 390 400
AVDKYLENPN DENEHDRFLK AKERLEGKHR EKMSEVMKEW EEAERQAKNL
410 420 430 440 450
PKADKKAVIQ HFQEKVESLE QEAAKQRQQL VETHMARVEA MLNDRRRIAL
460 470 480 490 500
ENYITALQAD PPRPRHVFNM LKKYVRAEQK DRQHTLKHFE HVRMVDPKKA
510 520 530 540 550
AQIRSQVMTH LRVINERMNQ SFSLLYKVPA VAEEIQDEVD ELFQKEQNYS
560 570 580 590 600
DDMVSNMVSD HRVSYGNDAL MPSLSETKTT VELLPVDGEF NIEDLQPWHS
610 620 630 640 650
FGVDSVPANT ENEVEPVDAR PAADRGLTTR PGSGLTNIKT EEISEVKMDS
660 670 680 690 700
EYRHDTAYEV HHQKLVFFAE EVGSNKGAII GLMVGGVVIA TVIVITLVML
710 720 730 740
KKKQYTTIHH GVVEVDAAVT PEERHLTKMQ QNGYENPTYK FFEQMQN
Length:747
Mass (Da):84,893
Last modified:November 1, 1996 - v1
Checksum:iA75E81885681D948
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S52417 mRNA. Translation: AAB24853.1.

Similar proteinsi

Entry informationi

Entry nameiQ91963_9PIPI
AccessioniPrimary (citable) accession number: Q91963
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)