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Protein
Submitted name:

ERCC2/XPD protein

Gene

ERCC2/XPD

Organism
Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HelicaseSAAS annotation, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ERCC2/XPD proteinImported
Gene namesi
Name:ERCC2/XPDImported
OrganismiXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)Imported
Taxonomic identifieri8083 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaeXiphophorus

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi8083.ENSXMAP00000003957.

Structurei

3D structure databases

ProteinModelPortaliQ91941.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 285279Helicase ATP-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains helicase ATP-binding domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG1131. Eukaryota.
COG1199. LUCA.
HOVERGENiHBG051498.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR006555. ATP-dep_Helicase_C.
IPR010614. DEAD_2.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR013020. DNA_helicase_DNA-repair_Rad3.
IPR010643. HBB.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006554. Helicase-like_DEXD_c2.
IPR027417. P-loop_NTPase.
IPR001945. RAD3/XPD.
[Graphical view]
PfamiPF06733. DEAD_2. 1 hit.
PF06777. HBB. 1 hit.
PF13307. Helicase_C_2. 1 hit.
[Graphical view]
PRINTSiPR00852. XRODRMPGMNTD.
SMARTiSM00488. DEXDc2. 1 hit.
SM00491. HELICc2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 4 hits.
TIGRFAMsiTIGR00604. rad3. 1 hit.
PROSITEiPS00690. DEAH_ATP_HELICASE. 1 hit.
PS51193. HELICASE_ATP_BIND_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91941-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNIEGLLV YFPYDYIYPE QYSYMLELKR TLDAKGHGVL EMPSGTGKTI
60 70 80 90 100
SLLSLIVAYQ RAFPLDVTKL IYCSRTVPEI EKVVEELRKL MEFYAKETGE
110 120 130 140 150
VNNFLALSLS SRKNLCIHPE VSSLRFGKEV DGKCHSLTAS YIRAQRHSNP
160 170 180 190 200
NQPVCRFYEE FDAVGRQVPL PAGIYNLDDL KDFGRRKGWC PYYLARYSIL
210 220 230 240 250
HANIVVYSYH YLLDPKIADL VSKELAKKSV VVFDEAHNID NVCIDSMSVN
260 270 280 290 300
ITRRTVDRCQ NNVDTLQNTI HKIKETDAAK LREEYRRLVE GLKEANVARE
310 320 330 340 350
TDIYLANPVL PDEVLQEAVP GSIRTAEHFV GFLRRFLEYL KARLRVQHVV
360 370 380 390 400
QESAPQFLKD IFDKVCIDRK PLRFCAERLQ CLLRTLEIAD IADFSAVTLI
410 420 430 440 450
SNFATLVSTY SQGFTIIIEP FEDRTPTIAN PVLHFSCMDP SIAIKPVFQR
460 470 480 490 500
FQSVIITSGT LSPLDIYPRI LDFRPVTMAS FTMTLARTCL CPLIVGRGND
510 520 530 540 550
QVALSSKFET REDFAVIRNY GNLLLEMSAV VPDGIVAFFT SYVYMENIVA
560 570 580 590 600
SWYEQGILEN IQKNKLIFIE TQDAAETSMA LEKYQEACEN GRGAILLSVA
610 620 630 640 650
RGKVSEGIDF VHHFGRAVIM FGVPYVYTQS RILKARLEYL RDQFQIREND
660 670 680 690 700
FLTFDAMRHA AQCLGRAIRG KTDYGLMIFA DKRYARSDKR GKLPRWIQEH
710 720 730 740 750
INDGSLNLTV DEAVQLSKHF LRQMAQPFRQ EDQLGLSLLT LEQLQSEEML
760
QKISQMAHQA
Length:760
Mass (Da):86,947
Last modified:November 1, 1996 - v1
Checksum:iC70A7F32835E3A7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17896 Genomic DNA. Translation: AAA85822.1.
PIRiI51720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17896 Genomic DNA. Translation: AAA85822.1.
PIRiI51720.

3D structure databases

ProteinModelPortaliQ91941.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8083.ENSXMAP00000003957.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1131. Eukaryota.
COG1199. LUCA.
HOVERGENiHBG051498.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR006555. ATP-dep_Helicase_C.
IPR010614. DEAD_2.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR013020. DNA_helicase_DNA-repair_Rad3.
IPR010643. HBB.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006554. Helicase-like_DEXD_c2.
IPR027417. P-loop_NTPase.
IPR001945. RAD3/XPD.
[Graphical view]
PfamiPF06733. DEAD_2. 1 hit.
PF06777. HBB. 1 hit.
PF13307. Helicase_C_2. 1 hit.
[Graphical view]
PRINTSiPR00852. XRODRMPGMNTD.
SMARTiSM00488. DEXDc2. 1 hit.
SM00491. HELICc2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 4 hits.
TIGRFAMsiTIGR00604. rad3. 1 hit.
PROSITEiPS00690. DEAH_ATP_HELICASE. 1 hit.
PS51193. HELICASE_ATP_BIND_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ91941_XIPMA
AccessioniPrimary (citable) accession number: Q91941
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.