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Protein
Submitted name:

ERCC2/XPD protein

Gene

ERCC2/XPD

Organism
Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ERCC2/XPD proteinImported
Gene namesi
Name:ERCC2/XPDImported
OrganismiXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)Imported
Taxonomic identifieri8083 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaeXiphophorus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ91941
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 285Helicase ATP-bindingInterPro annotationAdd BLAST279

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili256 – 276Sequence analysisAdd BLAST21
Coiled coili278 – 298Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1131 Eukaryota
COG1199 LUCA
HOVERGENiHBG051498

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR010643 HBB
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
IPR001945 RAD3/XPD
PANTHERiPTHR11472:SF1 PTHR11472:SF1, 1 hit
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF06777 HBB, 1 hit
PF13307 Helicase_C_2, 1 hit
PRINTSiPR00852 XRODRMPGMNTD
SMARTiView protein in SMART
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 4 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q91941-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNIEGLLV YFPYDYIYPE QYSYMLELKR TLDAKGHGVL EMPSGTGKTI
60 70 80 90 100
SLLSLIVAYQ RAFPLDVTKL IYCSRTVPEI EKVVEELRKL MEFYAKETGE
110 120 130 140 150
VNNFLALSLS SRKNLCIHPE VSSLRFGKEV DGKCHSLTAS YIRAQRHSNP
160 170 180 190 200
NQPVCRFYEE FDAVGRQVPL PAGIYNLDDL KDFGRRKGWC PYYLARYSIL
210 220 230 240 250
HANIVVYSYH YLLDPKIADL VSKELAKKSV VVFDEAHNID NVCIDSMSVN
260 270 280 290 300
ITRRTVDRCQ NNVDTLQNTI HKIKETDAAK LREEYRRLVE GLKEANVARE
310 320 330 340 350
TDIYLANPVL PDEVLQEAVP GSIRTAEHFV GFLRRFLEYL KARLRVQHVV
360 370 380 390 400
QESAPQFLKD IFDKVCIDRK PLRFCAERLQ CLLRTLEIAD IADFSAVTLI
410 420 430 440 450
SNFATLVSTY SQGFTIIIEP FEDRTPTIAN PVLHFSCMDP SIAIKPVFQR
460 470 480 490 500
FQSVIITSGT LSPLDIYPRI LDFRPVTMAS FTMTLARTCL CPLIVGRGND
510 520 530 540 550
QVALSSKFET REDFAVIRNY GNLLLEMSAV VPDGIVAFFT SYVYMENIVA
560 570 580 590 600
SWYEQGILEN IQKNKLIFIE TQDAAETSMA LEKYQEACEN GRGAILLSVA
610 620 630 640 650
RGKVSEGIDF VHHFGRAVIM FGVPYVYTQS RILKARLEYL RDQFQIREND
660 670 680 690 700
FLTFDAMRHA AQCLGRAIRG KTDYGLMIFA DKRYARSDKR GKLPRWIQEH
710 720 730 740 750
INDGSLNLTV DEAVQLSKHF LRQMAQPFRQ EDQLGLSLLT LEQLQSEEML
760
QKISQMAHQA
Length:760
Mass (Da):86,947
Last modified:November 1, 1996 - v1
Checksum:iC70A7F32835E3A7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17896 Genomic DNA Translation: AAA85822.1
PIRiI51720

Similar proteinsi

Entry informationi

Entry nameiQ91941_XIPMA
AccessioniPrimary (citable) accession number: Q91941
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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