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Protein

Proteasome subunit beta type

Gene

psmb8

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteaseUniRule annotation

Protein family/group databases

MEROPSiT01.012.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit beta typeUniRule annotation (EC:3.4.25.1UniRule annotation)
Gene namesi
Name:psmb8Imported
Synonyms:PSMB8Imported
ORF Names:XELAEV_18039145mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 8l

Organism-specific databases

XenbaseiXB-GENE-479068. psmb8.

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Nucleus UniRule annotation
  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotationSAAS annotation, ProteasomeUniRule annotation

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG108297.
KOiK02740.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiView protein in InterPro
IPR029055. Ntn_hydrolases_N.
IPR000243. Pept_T1A_subB.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
PfamiView protein in Pfam
PF00227. Proteasome. 1 hit.
PRINTSiPR00141. PROTEASOME.
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiView protein in PROSITE
PS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91787-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLTMCGPT QSHDWRMPLY GGTISPTIPF RVCNTELAVP PGYQPAKFLQ
60 70 80 90 100
HLEEGVDDVK IEPWHGTTTL AFKFQHGVIV AVDSRASAGS YISTIKFNKV
110 120 130 140 150
IEINPYLLGT MSGSAADCQY WERLLAKECR LYQLRNNSRI SVSAASKLMC
160 170 180 190 200
NMMLQYRGTG LSVGSMICGW DKKGPGLYYV DDNGTRLCGD IFSTGSGNSY
210 220 230 240 250
AYGVMDSGYR FDLTPEEAYD LGRRAISYAT HRDAYSGGCV NLYHMKEDGW
260 270
VKIGQFDVSD LLHKFTEEKN M
Length:271
Mass (Da):30,190
Last modified:November 1, 1996 - v1
Checksum:i3A33C668EEA0DC66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060388 mRNA. Translation: AAH60388.1.
D44540 mRNA. Translation: BAA07945.1.
CM004480 Genomic DNA. Translation: OCT67841.1.
PIRiI51536.
RefSeqiNP_001084323.1. NM_001090854.1.
UniGeneiXl.162.

Genome annotation databases

GeneIDi399439.
KEGGixla:399439.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ91787_XENLA
AccessioniPrimary (citable) accession number: Q91787
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported