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Protein
Submitted name:

Activin D

Gene

inhbc.1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionGrowth factorUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Activin DImported
Gene namesi
Name:inhbc.1Imported
Synonyms:actd-aImported
ORF Names:XELAEV_18013433mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 2l

Organism-specific databases

XenbaseiXB-GENE-866343. inhbc.1.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501051031128 – 367Sequence analysisAdd BLAST340

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini250 – 367TGF_BETA_2InterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG105613.
KOiK04667.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiView protein in InterPro
IPR029034. Cystine-knot_cytokine.
IPR001318. Inhibin_betaC.
IPR001839. TGF-b_C.
IPR001111. TGF-b_propeptide.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiView protein in Pfam
PF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
PRINTSiPR00672. INHIBINBC.
SMARTiView protein in SMART
SM00204. TGFB. 1 hit.
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiView protein in PROSITE
PS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91696-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRFQREGI CFYLLTLLGA LAASTQGLTK KSQCPSCGVQ DKEVMIELAK
60 70 80 90 100
QQILQKLHLK ERPNITHPVP RGAVANALRR LHLNKPRMEG LFGSNSWDSN
110 120 130 140 150
TENTDTDQQS YEIISFAETE YTNENSITLN FQFTRDKEQS AHVLQAHLWL
160 170 180 190 200
FFKANRTSQQ NETIRLYLVQ EAYSRRILIS EKLIEPRWTG WQTFSLKSML
210 220 230 240 250
QTFFDGGNKS LQLELNCDGC QDVPVLANPN NSHQPFLVAQ AKVHEQSHHA
260 270 280 290 300
TKRSLNCDQN SNLCCRKDYY VDFKDIGWND WIIKPEGYQI NYCMGLCPMH
310 320 330 340 350
IAGAPGMAAS FHTTVLNLIK ANNIQTAVNS CCVPTKRRPL SMLYFDRNNN
360
VLKTDIADMI VEACGCS
Length:367
Mass (Da):41,730
Last modified:November 1, 1996 - v1
Checksum:iC7E6334BD606FA04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC169414 mRNA. Translation: AAI69414.1.
D49543 mRNA. Translation: BAA08494.1.
CM004468 Genomic DNA. Translation: OCT95746.1.
PIRiJC4151.
RefSeqiNP_001079333.1. NM_001085864.1.
UniGeneiXl.945.

Genome annotation databases

GeneIDi378661.
KEGGixla:378661.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC169414 mRNA. Translation: AAI69414.1.
D49543 mRNA. Translation: BAA08494.1.
CM004468 Genomic DNA. Translation: OCT95746.1.
PIRiJC4151.
RefSeqiNP_001079333.1. NM_001085864.1.
UniGeneiXl.945.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi378661.
KEGGixla:378661.

Organism-specific databases

CTDi378661.
XenbaseiXB-GENE-866343. inhbc.1.

Phylogenomic databases

HOVERGENiHBG105613.
KOiK04667.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiView protein in InterPro
IPR029034. Cystine-knot_cytokine.
IPR001318. Inhibin_betaC.
IPR001839. TGF-b_C.
IPR001111. TGF-b_propeptide.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiView protein in Pfam
PF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
PRINTSiPR00672. INHIBINBC.
SMARTiView protein in SMART
SM00204. TGFB. 1 hit.
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiView protein in PROSITE
PS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ91696_XENLA
AccessioniPrimary (citable) accession number: Q91696
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.