ID   Q91639_XENLA            Unreviewed;       319 AA.
AC   Q91639;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   27-MAR-2024, entry version 121.
DE   SubName: Full=FOS-like antigen 2 L homeolog {ECO:0000313|RefSeq:NP_001094399.1};
DE   SubName: Full=Fos-related antigen-2 {ECO:0000313|EMBL:AAC59866.1};
GN   Name=fosl2.L {ECO:0000313|RefSeq:NP_001094399.1,
GN   ECO:0000313|Xenbase:XB-GENE-6252038};
GN   Synonyms=fosl2 {ECO:0000313|RefSeq:NP_001094399.1,
GN   ECO:0000313|Xenbase:XB-GENE-6252038}, gene 7
GN   {ECO:0000313|EMBL:AAC59866.1, ECO:0000313|RefSeq:NP_001094399.1};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|EMBL:AAC59866.1};
RN   [1] {ECO:0000313|EMBL:AAC59866.1, ECO:0000313|RefSeq:NP_001094399.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8700860; DOI=10.1073/pnas.93.5.1924;
RA   Brown D.D., Wang Z., Furlow J.D., Kanamori A., Schwartzman R.A., Remo B.F.,
RA   Pinder A.;
RT   "The thyroid hormone-induced tail resorption program during Xenopus laevis
RT   metamorphosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:1924-1929(1996).
RN   [2] {ECO:0000313|RefSeq:NP_001094399.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12454917; DOI=10.1002/dvdy.10174;
RA   Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA   Richardson P.;
RT   "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT   initiative.";
RL   Dev. Dyn. 225:384-391(2002).
RN   [3] {ECO:0000313|RefSeq:NP_001094399.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; U37374; AAC59866.1; -; mRNA.
DR   RefSeq; NP_001094399.1; NM_001100929.1.
DR   GeneID; 398055; -.
DR   KEGG; xla:398055; -.
DR   AGR; Xenbase:XB-GENE-6252038; -.
DR   CTD; 398055; -.
DR   Xenbase; XB-GENE-6252038; fosl2.L.
DR   OrthoDB; 4614365at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 398055; Expressed in zone of skin and 17 other cell types or tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd14721; bZIP_Fos; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   InterPro; IPR000837; AP-1.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   PANTHER; PTHR23351; FOS TRANSCRIPTION FACTOR-RELATED; 1.
DR   PANTHER; PTHR23351:SF25; FOS-RELATED ANTIGEN 2; 1.
DR   Pfam; PF00170; bZIP_1; 1.
DR   PRINTS; PR00042; LEUZIPPRFOS.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF57959; Leucine zipper domain; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
PE   2: Evidence at transcript level;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT   DOMAIN          128..191
FT                   /note="BZIP"
FT                   /evidence="ECO:0000259|PROSITE:PS50217"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          110..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..28
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   319 AA;  35188 MW;  295CF3CE536E8DFE CRC64;
     MYHDYPGNFD SSSRGSSSSP AQPEGYPSSI LSTSILQKFR TDMPGSSSAF IPTVNAITTS
     QDLQWMVQPT VITSMSNPYG RAHPYSHSVP NLASVTGHSA LQRPGVIKTI GTTAGRRRRD
     EQLSPEEEEK RRVRRERNKL AAAKCRNRRR ELTDKLQAET EKLEQEKSGL QKEIADLQKE
     KDKLEFMLVA HSPVCKISTD DRIISSQNVR PMKVVIKQEP VEEDIPSAKV IDKTQRSVIK
     PINIAGGFFN EEPLNTPVVM SSTPPTTPTT SNLVFTYPSV LDQDSSTSPS ESCSKAHRRS
     SSSGDQSSDS LNSPTLLAL
//