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Protein
Submitted name:

Potassium channel alpha subunit Kv2.1

Gene

kcnb1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel alpha subunit Kv2.1Imported
Gene namesi
Name:kcnb1Imported
Synonyms:XShab9Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-982940. kcnb1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei186 – 20823HelicalSequence analysisAdd
BLAST
Transmembranei228 – 24922HelicalSequence analysisAdd
BLAST
Transmembranei331 – 35121HelicalSequence analysisAdd
BLAST
Transmembranei363 – 38018HelicalSequence analysisAdd
BLAST
Transmembranei392 – 41625HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ91593.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 140110BTB (POZ)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili134 – 16128Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052225.
KOiK04885.

Family and domain databases

InterProiIPR000210. BTB/POZ_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003973. K_chnl_volt-dep_Kv2.
IPR004350. K_chnl_volt-dep_Kv2.1.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF03521. Kv2channel. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01514. KV21CHANNEL.
PR01491. KVCHANNEL.
PR01495. SHABCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91593-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGWMNKHGS RSTTSLPPDP MDIIRSKACS RRVKVNVGGL AHEVLWRTLD
60 70 80 90 100
RLPRTRLGKL RDCNTNECLM EICDDYNLEE NEYFFDRHPG AFTSILNFYR
110 120 130 140 150
TGKLHMMEEM CALSFSQELD YWGIDEIYLE SCCQARYHQK KEQMNEELKR
160 170 180 190 200
EAETLREKEG DEFDNTCCAD KRKKLWDLLE KPNSSVAAKI LAIISILFIV
210 220 230 240 250
LSTIALSLNT LPDLQAIDEF GQTTDNAQLA HVEAVCIAWF TMEYLLRFLS
260 270 280 290 300
SPNKWKFFKG PLNVIDLLAI LPYYVTIFLT ESNKSVLQFQ NVRRVVQIFR
310 320 330 340 350
IMRILRILKL ARHSTGLQSL GFTLRRSYNE LGLLILFLAM GIMIFSSLVF
360 370 380 390 400
FAEKDEDDTK FKSIPASFWW ATITMTTVGY GDIYPKTLLG KIVGGLCCIA
410 420 430 440 450
GVLVIALPIP IIVNNFSEFY KEQKRQEKAV KRREALERAK RNGSIVSMNM
460 470 480 490 500
KDAFARSVEL MDVVVEKTDE TSGRKDKVQD NHLSPSRWKW KKRTLSETSS
510 520 530 540 550
NKSFDAKEQG SPEKTRSGSS PQNLNVQQLE DIYNKMAKTQ SQPILNSKDL
560 570 580 590 600
NQPSKPAEEL EMGSIPGPTV PMLATHREGF IDMRSMSSID SFISCTAEFP
610 620 630 640 650
ESGRFSHSPL AILPYRMNVN SGQNTSHGYK ESRVRPLSSD VSRESFTEVH
660 670 680 690 700
PKTDLSRHAT YILESPKTLV KVKNPLMLRS LKVNFLEGET SSLLPAPNVL
710 720 730 740 750
SPTSHRQEGP SNQDTSFIYE HSVQSPETSL YTTASARTPS KSPEKHMAID
760 770 780 790 800
FTFHDANVHK YIDADTDDEG QLLDGLDSSP SKELLGTMSP KYNITKSGHR
810 820 830 840 850
TQRDNVHRGD KNHLEGAPFL SSSRYVGQNC IYATEGMTGR RQGNLETVKM
860 870
ENHISPQVHV LPGGGGGHSN KHNPSI
Length:876
Mass (Da):99,088
Last modified:November 1, 1996 - v1
Checksum:iA11AC5ADD1ED5C05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20343 mRNA. Translation: AAC59758.1.
RefSeqiNP_001079257.1. NM_001085788.1.
UniGeneiXl.344.

Genome annotation databases

GeneIDi378535.
KEGGixla:378535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20343 mRNA. Translation: AAC59758.1.
RefSeqiNP_001079257.1. NM_001085788.1.
UniGeneiXl.344.

3D structure databases

ProteinModelPortaliQ91593.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi378535.
KEGGixla:378535.

Organism-specific databases

CTDi3745.
XenbaseiXB-GENE-982940. kcnb1.

Phylogenomic databases

HOVERGENiHBG052225.
KOiK04885.

Family and domain databases

InterProiIPR000210. BTB/POZ_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003973. K_chnl_volt-dep_Kv2.
IPR004350. K_chnl_volt-dep_Kv2.1.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF03521. Kv2channel. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01514. KV21CHANNEL.
PR01491. KVCHANNEL.
PR01495. SHABCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Xenopus spinal neurons express Kv2 potassium channel transcripts during embryonic development."
    Burger C., Ribera A.B.
    J. Neurosci. 16:1412-1421(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Brain-eyeImported.

Entry informationi

Entry nameiQ91593_XENLA
AccessioniPrimary (citable) accession number: Q91593
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.