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Protein
Submitted name:

Potassium channel alpha subunit Kv2.2

Gene

kcnb2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel alpha subunit Kv2.2Imported
Gene namesi
Name:kcnb2Imported
Synonyms:XShab12Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-989395. kcnb2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei190 – 21223HelicalSequence analysisAdd
BLAST
Transmembranei265 – 28622HelicalSequence analysisAdd
BLAST
Transmembranei335 – 35622HelicalSequence analysisAdd
BLAST
Transmembranei368 – 38518HelicalSequence analysisAdd
BLAST
Transmembranei397 – 41721HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ91592.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 144110BTB (POZ)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili142 – 16928Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052225.
KOiK04886.

Family and domain databases

InterProiIPR000210. BTB/POZ_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003973. K_chnl_volt-dep_Kv2.
IPR005826. K_chnl_volt-dep_Kv2.2.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF03521. Kv2channel. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01515. KV22CHANNEL.
PR01491. KVCHANNEL.
PR01495. SHABCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91592-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKVPPGLN RKTSRSTLSL PPEPVEIIRS KACSRRVKIN VGGLNHEVLW
60 70 80 90 100
RTLDRLPRTR LGKLRDCNTH ESLLDVCDDY NLNENEYFFD RHPGAFTSIL
110 120 130 140 150
NFYRTGKLHM MEEMCALSFG QELDFWGIDE IYLESCCQAR YHQKKEQMNE
160 170 180 190 200
ELRREAETLR EREGEEFDNT CCPEKTKKLW DLLEKPNSSV AAKVLAIISI
210 220 230 240 250
LFIVLSTIAL SLNTLPDLQE IDEFGQPNDN PQLAHVEAVC IAWFTMEYLL
260 270 280 290 300
RFLSSPNKWK FFKGPLNIID LLAILPYYVT IFLTASNKSV LQFQNVRRVV
310 320 330 340 350
QIFRIMRILR ILKLARHSTG LQSLGFTLRR SYNELGLLIL FLAMGIMIFS
360 370 380 390 400
SLVFFAEKDE DATKFTSIPA SFWWATITMT TVGYGDIYPK TLLGKIIGGL
410 420 430 440 450
CCIAGVLVIA LPIPIIVNNF SEFYKEQKRQ EKAIKRREAL ERAKRNGSIV
460 470 480 490 500
SMNLKDAFAR SMELIDIAVD KSEDGSNKME KPSDNHLSPS RWKWSRRTLS
510 520 530 540 550
DTSSNKSFDN KYQEVSQHDS QEQLNNASSS PQHLSAQKLE ELYNEITKAQ
560 570 580 590 600
SHPSVNSSFQ EQAAVPPAYE EEIEMEEVST KKTQLSVAQK DIVTDMRSVS
610 620 630 640 650
SIDSFASCAT DFTETERSPL TPYPGSNLEI RFPSYTVPEE GHGGNTAQFL
660 670 680 690 700
PRSKCMGFAP KDVTFEYKLS EHPIKNDNET PKILLQDQAG NEVESPEFSL
710 720 730 740 750
KRNHPLRSRS LKVNFKNPKS HSQPATANFS SALPVNMIDH PLYTHLQLST
760 770 780 790 800
IFLQDYQSQE QPSNLQTDSS SDHSRSLQVS PKHNPKLFAL SSNMKSSFTE
810 820 830 840 850
IGPEDEDFMQ ICGEKNDTQE NMKVNCIKEK PEGHFVNLET SLLSPQKTIS
860 870 880 890
QNCTQDTYSQ RRKQIRKTAK WKIICLSQKS TRTQAKQVIV QLMRPACD
Length:898
Mass (Da):102,410
Last modified:November 1, 1996 - v1
Checksum:i10FFD022CE5078BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20342 mRNA. Translation: AAC59757.1.
RefSeqiNP_001079256.1. NM_001085787.1.
UniGeneiXl.343.

Genome annotation databases

GeneIDi378534.
KEGGixla:378534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20342 mRNA. Translation: AAC59757.1.
RefSeqiNP_001079256.1. NM_001085787.1.
UniGeneiXl.343.

3D structure databases

ProteinModelPortaliQ91592.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi378534.
KEGGixla:378534.

Organism-specific databases

CTDi378534.
XenbaseiXB-GENE-989395. kcnb2.

Phylogenomic databases

HOVERGENiHBG052225.
KOiK04886.

Family and domain databases

InterProiIPR000210. BTB/POZ_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003973. K_chnl_volt-dep_Kv2.
IPR005826. K_chnl_volt-dep_Kv2.2.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF03521. Kv2channel. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01515. KV22CHANNEL.
PR01491. KVCHANNEL.
PR01495. SHABCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ91592_XENLA
AccessioniPrimary (citable) accession number: Q91592
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.