Q91592 (Q91592_XENLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Potassium channel alpha subunit Kv2.2 EMBL AAC59757.1

Gene names

Name:	kcnb2 Xenbase XB-GENE-989395
Synonyms:	XShab12 EMBL AAC59757.1

Organism

Xenopus laevis (African clawed frog) EMBL AAC59757.1

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	898 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Potassium transport Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS003091
Ligand	Potassium
Molecular function	Ion channel Potassium channel SAAS SAAS003091 Voltage-gated channel SAAS SAAS003091
Gene Ontology (GO)
Biological_process	protein homooligomerization Inferred from electronic annotation. Source: InterPro
Cellular_component	voltage-gated potassium channel complex Inferred from electronic annotation. Source: InterPro
Molecular_function	voltage-gated potassium channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q91592 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 10FFD022CE5078BA	FASTA	898	102,410
	10 20 30 40 50 60 MAEKVPPGLN RKTSRSTLSL PPEPVEIIRS KACSRRVKIN VGGLNHEVLW RTLDRLPRTR 70 80 90 100 110 120 LGKLRDCNTH ESLLDVCDDY NLNENEYFFD RHPGAFTSIL NFYRTGKLHM MEEMCALSFG 130 140 150 160 170 180 QELDFWGIDE IYLESCCQAR YHQKKEQMNE ELRREAETLR EREGEEFDNT CCPEKTKKLW 190 200 210 220 230 240 DLLEKPNSSV AAKVLAIISI LFIVLSTIAL SLNTLPDLQE IDEFGQPNDN PQLAHVEAVC 250 260 270 280 290 300 IAWFTMEYLL RFLSSPNKWK FFKGPLNIID LLAILPYYVT IFLTASNKSV LQFQNVRRVV 310 320 330 340 350 360 QIFRIMRILR ILKLARHSTG LQSLGFTLRR SYNELGLLIL FLAMGIMIFS SLVFFAEKDE 370 380 390 400 410 420 DATKFTSIPA SFWWATITMT TVGYGDIYPK TLLGKIIGGL CCIAGVLVIA LPIPIIVNNF 430 440 450 460 470 480 SEFYKEQKRQ EKAIKRREAL ERAKRNGSIV SMNLKDAFAR SMELIDIAVD KSEDGSNKME 490 500 510 520 530 540 KPSDNHLSPS RWKWSRRTLS DTSSNKSFDN KYQEVSQHDS QEQLNNASSS PQHLSAQKLE 550 560 570 580 590 600 ELYNEITKAQ SHPSVNSSFQ EQAAVPPAYE EEIEMEEVST KKTQLSVAQK DIVTDMRSVS 610 620 630 640 650 660 SIDSFASCAT DFTETERSPL TPYPGSNLEI RFPSYTVPEE GHGGNTAQFL PRSKCMGFAP 670 680 690 700 710 720 KDVTFEYKLS EHPIKNDNET PKILLQDQAG NEVESPEFSL KRNHPLRSRS LKVNFKNPKS 730 740 750 760 770 780 HSQPATANFS SALPVNMIDH PLYTHLQLST IFLQDYQSQE QPSNLQTDSS SDHSRSLQVS 790 800 810 820 830 840 PKHNPKLFAL SSNMKSSFTE IGPEDEDFMQ ICGEKNDTQE NMKVNCIKEK PEGHFVNLET 850 860 870 880 890 SLLSPQKTIS QNCTQDTYSQ RRKQIRKTAK WKIICLSQKS TRTQAKQVIV QLMRPACD

References

[1]	"Xenopus spinal neurons express Kv2 potassium channel transcripts during embryonic development." Burger C., Ribera A.B. J. Neurosci. 16:1412-1421(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain-eye EMBL AAC59757.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U20342 mRNA. Translation: AAC59757.1.
RefSeq	NP_001079256.1. NM_001085787.1.
UniGene	Xl.343.
3D structure databases
HSSP	HSSP built from PDB template 3KVT based on UniProtKB O76457.
ProteinModelPortal	Q91592.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	378534.
KEGG	xla:378534.
Organism-specific databases
CTD	378534.
Xenbase	XB-GENE-989395. kcnb2.
Phylogenomic databases
HOVERGEN	HBG052225.
KO	K04886.
Family and domain databases
Gene3D	3.30.710.10. 1 hit.
InterPro	IPR000210. BTB/POZ-like. IPR011333. BTB/POZ_fold. IPR005821. Ion_trans_dom. IPR003091. K_chnl. IPR003968. K_chnl_volt-dep_Kv. IPR003973. K_chnl_volt-dep_Kv2. IPR005826. K_chnl_volt-dep_Kv2.2. IPR003131. T1-type_BTB. [Graphical view]
PANTHER	PTHR11537. PTHR11537. 1 hit.
Pfam	PF00520. Ion_trans. 1 hit. PF02214. K_tetra. 1 hit. PF03521. Kv2channel. 1 hit. [Graphical view]
PRINTS	PR00169. KCHANNEL. PR01515. KV22CHANNEL. PR01491. KVCHANNEL. PR01495. SHABCHANNEL.
SMART	SM00225. BTB. 1 hit. [Graphical view]
SUPFAM	SSF54695. BTB/POZ_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q91592_XENLA

Accession

Primary (citable) accession number: Q91592

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)