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Protein
Submitted name:

Potassium channel alpha subunit Kv2.2

Gene

kcnb2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel alpha subunit Kv2.2Imported
Gene namesi
Name:kcnb2Imported
Synonyms:XShab12Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-989395. kcnb2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei190 – 212HelicalSequence analysisAdd BLAST23
Transmembranei265 – 286HelicalSequence analysisAdd BLAST22
Transmembranei335 – 356HelicalSequence analysisAdd BLAST22
Transmembranei368 – 385HelicalSequence analysisAdd BLAST18
Transmembranei397 – 417HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ91592.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 144BTBInterPro annotationAdd BLAST110

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili142 – 169Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052225.

Family and domain databases

InterProiView protein in InterPro
IPR000210. BTB/POZ_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003973. K_chnl_volt-dep_Kv2.
IPR005826. K_chnl_volt-dep_Kv2.2.
IPR011333. SKP1/BTB/POZ_sf.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiView protein in Pfam
PF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF03521. Kv2channel. 1 hit.
PRINTSiPR00169. KCHANNEL.
PR01515. KV22CHANNEL.
PR01491. KVCHANNEL.
PR01495. SHABCHANNEL.
SMARTiView protein in SMART
SM00225. BTB. 1 hit.
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91592-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKVPPGLN RKTSRSTLSL PPEPVEIIRS KACSRRVKIN VGGLNHEVLW
60 70 80 90 100
RTLDRLPRTR LGKLRDCNTH ESLLDVCDDY NLNENEYFFD RHPGAFTSIL
110 120 130 140 150
NFYRTGKLHM MEEMCALSFG QELDFWGIDE IYLESCCQAR YHQKKEQMNE
160 170 180 190 200
ELRREAETLR EREGEEFDNT CCPEKTKKLW DLLEKPNSSV AAKVLAIISI
210 220 230 240 250
LFIVLSTIAL SLNTLPDLQE IDEFGQPNDN PQLAHVEAVC IAWFTMEYLL
260 270 280 290 300
RFLSSPNKWK FFKGPLNIID LLAILPYYVT IFLTASNKSV LQFQNVRRVV
310 320 330 340 350
QIFRIMRILR ILKLARHSTG LQSLGFTLRR SYNELGLLIL FLAMGIMIFS
360 370 380 390 400
SLVFFAEKDE DATKFTSIPA SFWWATITMT TVGYGDIYPK TLLGKIIGGL
410 420 430 440 450
CCIAGVLVIA LPIPIIVNNF SEFYKEQKRQ EKAIKRREAL ERAKRNGSIV
460 470 480 490 500
SMNLKDAFAR SMELIDIAVD KSEDGSNKME KPSDNHLSPS RWKWSRRTLS
510 520 530 540 550
DTSSNKSFDN KYQEVSQHDS QEQLNNASSS PQHLSAQKLE ELYNEITKAQ
560 570 580 590 600
SHPSVNSSFQ EQAAVPPAYE EEIEMEEVST KKTQLSVAQK DIVTDMRSVS
610 620 630 640 650
SIDSFASCAT DFTETERSPL TPYPGSNLEI RFPSYTVPEE GHGGNTAQFL
660 670 680 690 700
PRSKCMGFAP KDVTFEYKLS EHPIKNDNET PKILLQDQAG NEVESPEFSL
710 720 730 740 750
KRNHPLRSRS LKVNFKNPKS HSQPATANFS SALPVNMIDH PLYTHLQLST
760 770 780 790 800
IFLQDYQSQE QPSNLQTDSS SDHSRSLQVS PKHNPKLFAL SSNMKSSFTE
810 820 830 840 850
IGPEDEDFMQ ICGEKNDTQE NMKVNCIKEK PEGHFVNLET SLLSPQKTIS
860 870 880 890
QNCTQDTYSQ RRKQIRKTAK WKIICLSQKS TRTQAKQVIV QLMRPACD
Length:898
Mass (Da):102,410
Last modified:November 1, 1996 - v1
Checksum:i10FFD022CE5078BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20342 mRNA. Translation: AAC59757.1.
RefSeqiNP_001079256.1. NM_001085787.1.
UniGeneiXl.343.

Genome annotation databases

GeneIDi378534.

Similar proteinsi

Entry informationi

Entry nameiQ91592_XENLA
AccessioniPrimary (citable) accession number: Q91592
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)