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Protein
Submitted name:

Endothelin receptor

Gene
N/A
Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Endothelin receptorImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei70 – 9526HelicalSequence analysisAdd
BLAST
Transmembranei107 – 13226HelicalSequence analysisAdd
BLAST
Transmembranei152 – 17019HelicalSequence analysisAdd
BLAST
Transmembranei191 – 21626HelicalSequence analysisAdd
BLAST
Transmembranei246 – 27227HelicalSequence analysisAdd
BLAST
Transmembranei293 – 31321HelicalSequence analysisAdd
BLAST
Transmembranei333 – 36129HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 415391Sequence analysisPRO_5004320808Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ91548.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini86 – 358273G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG051443.

Family and domain databases

InterProiIPR000499. Endthln_rcpt.
IPR002175. ETA_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00570. ENDOTHELINAR.
PR00366. ENDOTHELINR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91548-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGNILRFTV LLVLAGIAVS SSFGEYYQNR TDASTDFTML NRSHTSPVRK
60 70 80 90 100
GNRSADLCPE KTKINHVFKY INTILSCTIF IIGMVGNATL LRIIYQNKCM
110 120 130 140 150
RNGPNALIAS LALGDLIYIV IDIPIIVFKL LGQRWPFDQS PVGAFLCKLV
160 170 180 190 200
PFIQKASVGI TVLNLCALSV DRYRAVPSWS RVQGSGIPLI TAIEIISIWV
210 220 230 240 250
LSFVLAIPEA IGFVMVPFEY RGEQFRTCMF HATSPFMMFY KNAKDWWLFG
260 270 280 290 300
LYFCVPLACT GVFYTMMTCE MLHQRKGSLR IALSEHLKQR REVAKTVFCL
310 320 330 340 350
VVIFALCWFP LHLSRIIKNT IYNELDPSRC ELLSFLLVMD FISINLAALN
360 370 380 390 400
SCINPIALYF VSKKFKNCFQ SCLCCCCQSK THINTAPMNV TSIQWKNHDQ
410
NYYGADRSIH KDSIN
Length:415
Mass (Da):47,004
Last modified:November 1, 1996 - v1
Checksum:i98DA919097085D70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U06633 Unassigned DNA. Translation: AAA19570.1.
PIRiA54126.
UniGeneiXl.56668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U06633 Unassigned DNA. Translation: AAA19570.1.
PIRiA54126.
UniGeneiXl.56668.

3D structure databases

ProteinModelPortaliQ91548.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG051443.

Family and domain databases

InterProiIPR000499. Endthln_rcpt.
IPR002175. ETA_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00570. ENDOTHELINAR.
PR00366. ENDOTHELINR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and characterization of a novel endothelin receptor from Xenopus heart."
    Kumar C., Mwangi V., Nuthulaganti P., Wu H.L., Pullen M., Brun K., Aiyar H., Morris R.A., Naughton R., Nambi P.
    J. Biol. Chem. 269:13414-13420(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HeartImported.

Entry informationi

Entry nameiQ91548_XENLA
AccessioniPrimary (citable) accession number: Q91548
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: December 9, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.