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Protein

Creatine transporter

Gene
N/A
Organism
Torpedo marmorata (Marbled electric ray)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the uptake of creatine.

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Ion transport, Sodium transport, Symport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Creatine transporter
OrganismiTorpedo marmorata (Marbled electric ray)
Taxonomic identifieri7788 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaTorpediniformesTorpedinidaeTorpedo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Topological domaini66 – 71ExtracellularSequence analysis6
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Topological domaini93 – 122CytoplasmicSequence analysisAdd BLAST30
Transmembranei123 – 143HelicalSequence analysisAdd BLAST21
Topological domaini144 – 207ExtracellularSequence analysisAdd BLAST64
Transmembranei208 – 228HelicalSequence analysisAdd BLAST21
Topological domaini229 – 246CytoplasmicSequence analysisAdd BLAST18
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21
Topological domaini268 – 281ExtracellularSequence analysisAdd BLAST14
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Topological domaini303 – 318CytoplasmicSequence analysisAdd BLAST16
Transmembranei319 – 339HelicalSequence analysisAdd BLAST21
Topological domaini340 – 371ExtracellularSequence analysisAdd BLAST32
Transmembranei372 – 392HelicalSequence analysisAdd BLAST21
Topological domaini393 – 421CytoplasmicSequence analysisAdd BLAST29
Transmembranei422 – 442HelicalSequence analysisAdd BLAST21
Topological domaini443 – 456ExtracellularSequence analysisAdd BLAST14
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Topological domaini478 – 497CytoplasmicSequence analysisAdd BLAST20
Transmembranei498 – 518HelicalSequence analysisAdd BLAST21
Topological domaini519 – 537ExtracellularSequence analysisAdd BLAST19
Transmembranei538 – 558HelicalSequence analysisAdd BLAST21
Topological domaini559 – 611CytoplasmicSequence analysisAdd BLAST53

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002147781 – 611Creatine transporterAdd BLAST611

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi157N-linked (GlcNAc...)Sequence analysis1
Glycosylationi171N-linked (GlcNAc...)Sequence analysis1
Glycosylationi525N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ91502.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG071421.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91502-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSRAVRRCP GHLCKEMRAP RRAQPPDVPA GEPGSRVTWS RQMDFIMSCV
60 70 80 90 100
GFAVGLGNVW RFPYLCYKNG GGVFLIPYLL VAVFGGIPIF FLEISLGQFM
110 120 130 140 150
KAGGINAWNI APLFKGLGYA SMVIVFFCNT YYILVLTWSS FYLVQSFSSP
160 170 180 190 200
LPWASCNNTW NTAACYEAGA NASTEIYPPT APAQSSIVQF WERRVLRLSS
210 220 230 240 250
GLGDVGEIGW ELTLCLTATW MLVYFCIWKG VKTSGKVVYV TATFPYIILV
260 270 280 290 300
ILLVRGVTLH GAVQGIVYYL QPDWGKLGEA QVWIDAGTQI FFSYAIGLGT
310 320 330 340 350
LTALGSYNQL HNDCYKDAFI LSLVNSATSF FAGLVVFSIL GFMAVEEGVD
360 370 380 390 400
ISVVAESGPG LAFIAYPKAV TLMPFPQVWA VLFFIMLLCL GLGSQFVGVE
410 420 430 440 450
GFVTAILDLW PSKFSFRYLR EVVVAMVICL SFLIDLSMIT EGGMYIFQIF
460 470 480 490 500
DYYSASGTTL LWTAFWECVA VAWVYGGDRY LDDLAWMLGY RPWALVKWCW
510 520 530 540 550
SVITPLVCMG IFTFHLVNYK PLTYNKTYTY PWWGEAIGWC LALASMLCVP
560 570 580 590 600
TTVLYSLSRG RGSLKERWRK LTTPVWASHH LAYKMAGAKI NQPCEGVVSC
610
EEKVVIFESV L
Length:611
Mass (Da):68,099
Last modified:November 1, 1996 - v1
Checksum:iDAF3DB3A5C5299AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77306 mRNA. Translation: CAA54512.1.
PIRiS46260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77306 mRNA. Translation: CAA54512.1.
PIRiS46260.

3D structure databases

ProteinModelPortaliQ91502.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG071421.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSC6A8_TORMA
AccessioniPrimary (citable) accession number: Q91502
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: November 1, 1996
Last modified: October 1, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.