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Protein

Parvalbumin beta 2

Gene
N/A
Organism
Salmo salar (Atlantic salmon)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi51Calcium 1By similarity1
Metal bindingi53Calcium 1By similarity1
Metal bindingi55Calcium 1By similarity1
Metal bindingi57Calcium 1; via carbonyl oxygenBy similarity1
Metal bindingi59Calcium 1By similarity1
Metal bindingi62Calcium 1By similarity1
Metal bindingi90Calcium 2By similarity1
Metal bindingi92Calcium 2By similarity1
Metal bindingi94Calcium 2By similarity1
Metal bindingi101Calcium 2By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi51 – 621PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi90 – 1012PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionMuscle protein
LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Parvalbumin beta 2
Alternative name(s):
Major allergen Sal s 1
Allergen: Sal s 1
OrganismiSalmo salar (Atlantic salmon)
Taxonomic identifieri8030 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeSalmo
Proteomesi
  • UP000087266 Componenti: Genome assembly

Subcellular locationi

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei6117. Sal s 1.0201.
619. Sal s 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000736202 – 108Parvalbumin beta 2Add BLAST107

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Structurei

3D structure databases

ProteinModelPortaliQ91483.
SMRiQ91483.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 73EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini77 – 108EF-hand 2PROSITE-ProRule annotationAdd BLAST32

Sequence similaritiesi

Belongs to the parvalbumin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

HOVERGENiHBG107490.

Family and domain databases

InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR008080. Parvalbumin.
PANTHERiPTHR11653. PTHR11653. 1 hit.
PfamiView protein in Pfam
PF13499. EF-hand_7. 1 hit.
SMARTiView protein in SMART
SM00054. EFh. 2 hits.
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q91483-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFAGLNDAD VAAALAACTA ADSFNHKAFF AKVGLASKSS DDVKKAFYVI
60 70 80 90 100
DQDKSGFIEE DELKLFLQNF SASARALTDA ETKAFLADGD KDGDGMIGVD

EFAAMIKG
Length:108
Mass (Da):11,383
Last modified:January 23, 2007 - v3
Checksum:i537879026F864DA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97825 mRNA. Translation: CAA66404.2.
RefSeqiNP_001117189.1. NM_001123717.1.
UniGeneiSsa.23515.

Genome annotation databases

GeneIDi100137050.
KEGGisasa:100137050.

Similar proteinsi

Entry informationi

Entry nameiPRVB2_SALSA
AccessioniPrimary (citable) accession number: Q91483
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 88 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families