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Protein
Submitted name:

Tyrosinase

Gene

tyrosinase

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TyrosinaseImported
Gene namesi
Name:tyrosinaseImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei474 – 498HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500431925419 – 529Sequence analysisAdd BLAST511

Proteomic databases

PaxDbiQ91436.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000027812.

Structurei

3D structure databases

ProteinModelPortaliQ91436.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini202 – 219Tyrosinase_Cu-bdInterPro annotationAdd BLAST18
Domaini383 – 394Tyrosinase_Cu-bdInterPro annotationAdd BLAST12

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEZU. Eukaryota.
ENOG410Y42I. LUCA.
HOVERGENiHBG003553.

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSiPR00092. TYROSINASE.
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS00497. TYROSINASE_1. 1 hit.
PS00498. TYROSINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91436-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLFAMGLLL VILQPSTGQF PRVCANTQSL LRKECCPPWD GDGTPCGERS
60 70 80 90 100
NRGTCQRILL SQAPLGPQFP FSGVDDREDW PSVFYNRTCR CRGNFMGFNC
110 120 130 140 150
GECKFGFSGQ NCTERRLRTR RNIFQLTISE KDKFLAYLNL AKNIPSKDYV
160 170 180 190 200
IATGTYAQMN NGSNPMFRNI NVYDLFVWMH YYASRDTLLG GSNVWRDIDF
210 220 230 240 250
AHEAPGFLPW HRAFLLLWER EIQKITGDEN FTIPYWDWRD AEDCVICTDE
260 270 280 290 300
YMGGQHPTNP NLLSPASFFS SWQVICTQSE EYNSQQALCN ATSEGPILRN
310 320 330 340 350
PGNNDKSRTP RLPSSSEVEF CLTLTQYESG SMDKMANYSF RNTLEGFADP
360 370 380 390 400
HTAISNISQS GLHNALHIYM NGSMSQVQGS ANDPIFILHH AFVDSIFERW
410 420 430 440 450
LRRHRPMLEV YPAANAPIGH NRENYMVPFI PLYRNEEFFI SSRELGYDYE
460 470 480 490 500
YLQEPALGSF QDFLIPYLKQ AHQIWPWLVG AAVIGGIITA VLSGLILACR
510 520
KKRKGTSPEI QPLLTESEDY NNVSYQSHF
Length:529
Mass (Da):60,429
Last modified:November 1, 1996 - v1
Checksum:i428107F04C3CD9F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S81675 mRNA. Translation: AAB36375.1.
UniGeneiGga.928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S81675 mRNA. Translation: AAB36375.1.
UniGeneiGga.928.

3D structure databases

ProteinModelPortaliQ91436.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000027812.

Proteomic databases

PaxDbiQ91436.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IEZU. Eukaryota.
ENOG410Y42I. LUCA.
HOVERGENiHBG003553.

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSiPR00092. TYROSINASE.
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS00497. TYROSINASE_1. 1 hit.
PS00498. TYROSINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ91436_CHICK
AccessioniPrimary (citable) accession number: Q91436
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.