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Protein
Submitted name:

Drosophila seven-up homolog/mammalian ARP-1 homolog

Gene

nr2f2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi84 – 159Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

  • lymphangiogenesis Source: ZFIN
  • lymphatic endothelial cell fate commitment Source: ZFIN
  • regulation of transcription involved in venous endothelial cell fate commitment Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-UniRule
  • venous blood vessel development Source: ZFIN

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Drosophila seven-up homolog/mammalian ARP-1 homologImported
Submitted name:
Nuclear receptor subfamily 2, group F, member 2Imported
Gene namesi
Name:nr2f2Imported
Synonyms:svp[40]Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-990415-252. nr2f2.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000040926.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000059975.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 159Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118948.
HOGENOMiHOG000260820.
HOVERGENiHBG005606.
KOiK08548.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR003068. COUP_TF.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01282. COUPTNFACTOR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91430-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMVVWRGSQ DDVAETHGTL SSQTQGGLSL PTPQPGQLGL TASQVAPPTP
60 70 80 90 100
QTPVQGPPNN NNNTQSTPTN QTTQSQSEKQ QPQHIECVVC GDKSSGKHYG
110 120 130 140 150
QFTCEGCKSF FKRSVRRNLT YTCRANRNCP IDQHHRNQCQ YCRLKKCLKV
160 170 180 190 200
GMRREAVQRG RMPPTQPHHG QFALTNGDPL HCHSYLSGYI SLLLRAEPYP
210 220 230 240 250
TSRYGSQCMQ PNNIMGIENI CELAARMLFS AVEWARNIPF FPDLQITDQV
260 270 280 290 300
ALLRLTWSEL FVLNAAQCSM PLHVAPLLAA AGLHASPMSA DRVVAFMDHI
310 320 330 340 350
RIFQEQVEKL KALHVDSAEY SCLKAIVLFT SDACGLSDVA HVESLQEKSQ
360 370 380 390 400
CALEEYVRSQ YPNQPTRFGK LLLRLPSLRT VSSSVIEQLF FVRLVGKTPI
410 420
ETLIRDMLLS GSSFNWPYMS IQ
Length:422
Mass (Da):47,106
Last modified:November 1, 1996 - v1
Checksum:i50A7F308A3582E21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX569787 Genomic DNA. No translation available.
BX936364 Genomic DNA. No translation available.
S80986 mRNA. Translation: AAA99309.1.
RefSeqiNP_571258.1. NM_131183.1.
UniGeneiDr.77152.

Genome annotation databases

EnsembliENSDART00000130163; ENSDARP00000107285; ENSDARG00000040926.
GeneIDi30424.
KEGGidre:30424.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX569787 Genomic DNA. No translation available.
BX936364 Genomic DNA. No translation available.
S80986 mRNA. Translation: AAA99309.1.
RefSeqiNP_571258.1. NM_131183.1.
UniGeneiDr.77152.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000059975.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000130163; ENSDARP00000107285; ENSDARG00000040926.
GeneIDi30424.
KEGGidre:30424.

Organism-specific databases

CTDi7026.
ZFINiZDB-GENE-990415-252. nr2f2.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118948.
HOGENOMiHOG000260820.
HOVERGENiHBG005606.
KOiK08548.

Gene expression databases

BgeeiENSDARG00000040926.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR003068. COUP_TF.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01282. COUPTNFACTOR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ91430_DANRE
AccessioniPrimary (citable) accession number: Q91430
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.